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|Application / Reactivity||Rat (Rattus)||Human||Mouse (Murine)||Chicken||Dog (Canine)||Pig (Porcine)||Rabbit||Zebrafish (Danio rerio)||Frog||Orang-Utan|
|Immunofluorescence (fixed cells) (IF/ICC)||1 Antibodies|
|Western Blotting (WB)||131 Antibodies||93 Antibodies||87 Antibodies||5 Antibodies||8 Antibodies||4 Antibodies||5 Antibodies||2 Antibodies||2 Antibodies||1 Antibodies|
|Radioimmunoassay (RIA)||21 Antibodies||22 Antibodies||17 Antibodies|
|Antigen||Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Antibodies|
|Epitope||AA 6-23 Alternatives|
|Reactivity||Dog (Canine), Chicken, Frog, Human, Mouse (Murine), Orang-Utan, Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio) Alternatives|
|Conjugate||This CAMK2A antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-CAMK2A AntibodyTarget Details CAMK2A Application Details Handling References for anti-CAMK2A Antibody (ABIN401305) Images
|Specificity||This antibody is directed against human CaM Kinase II protein.|
Species reactivity (expected):Mouse, Rat, Canine, Orangutan, Zebrafish, Chicken, Porcine, Rabbit, Frog.
Species reactivity (tested):Human.
|Immunogen||Synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein|
Target Details CAMK2AProduct Details anti-CAMK2A Antibody Application Details Handling References for anti-CAMK2A Antibody (ABIN401305) Images back to top
|Alternative Name||CAMK2A (CAMK2A Antibody Abstract)|
|Background||CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968|
|Pathways||WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction|
Application DetailsProduct Details anti-CAMK2A Antibody Target Details CAMK2A Handling References for anti-CAMK2A Antibody (ABIN401305) Images back to top
ELISA: 1/4,000 - 1/20,000. Western Blot: 1/1,000 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2A Antibody Target Details CAMK2A Application Details References for anti-CAMK2A Antibody (ABIN401305) Images back to top
|Concentration||1.57 mg/mL (by UV absorbance at 280 nm)|
|Buffer||0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azi|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
References for anti-CAMK2A Antibody (ABIN401305)Product Details anti-CAMK2A Antibody Target Details CAMK2A Application Details Handling Images back to top
Lin, Kapiloff, Durgerian, Tatemoto, Russo, Hanson, Schulman, Rosenfeld: "Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 16, pp. 5962-6, 1987
ImagesProduct Details anti-CAMK2A Antibody Target Details CAMK2A Application Details Handling References for anti-CAMK2A Antibody (ABIN401305) back to top