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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)||Xenopus laevis|
|Western Blotting (WB)||119 Antibodies||65 Antibodies||81 Antibodies||7 Antibodies|
|Radioimmunoassay (RIA)||4 Antibodies||23 Antibodies||3 Antibodies|
|Proximity Ligation Assay (PLA)||2 Antibodies|
|Immunoprecipitation (IP)||5 Antibodies||27 Antibodies||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||12 Antibodies||15 Antibodies||29 Antibodies||1 Antibodies|
|Immunohistochemistry (IHC)||13 Antibodies||29 Antibodies|
|Antigen||Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus), Xenopus laevis Alternatives|
|Conjugate||This CAMK2A antibody is un-conjugated Alternatives|
Dot Blot (DB), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-CAMK2A AntibodyTarget Details CAMK2A Application Details Handling References for anti-CAMK2A Antibody (ABIN265086) Images
|Specificity||This antibody reacts to CAMK2A / CaMK II alpha (pThr 286). Antibody detects only phosphorylated protein and does not detect non-phosphorylated protein as shown by the lack of ability of a non-phospho peptide to block the antibody activity.|
|Immunogen||Synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphorylated-Thr286 found in rat brain CaM Kinase II|
Target Details CAMK2AProduct Details anti-CAMK2A Antibody Application Details Handling References for anti-CAMK2A Antibody (ABIN265086) Images back to top
|Alternative Name||CAMK2A (CAMK2A Antibody Abstract)|
|Background||Calcium/calmodulin kinase II (CaM Kinase II) is a multi-functional calcium and calmodulin-dependent protein kinase that mediates cellular responses to second messengers. The antibody was raised against a synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphorylated-Thr286 found in rat brain CaM Kinase II. Phosphorylation of Thr286 produces an autonomously active form of CaM Kinase II.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968|
|Pathways||WNT Signaling, Interferon-gamma Pathway|
Application DetailsProduct Details anti-CAMK2A Antibody Target Details CAMK2A Handling References for anti-CAMK2A Antibody (ABIN265086) Images back to top
Western Blot: 1: 1000 dilution to provide for 10 miniblots. Dot Blot: 1: 1000 dilution to provide for 10 miniblots.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2A Antibody Target Details CAMK2A Application Details References for anti-CAMK2A Antibody (ABIN265086) Images back to top
|Buffer||HEPES ( pH 7.5) solution containing 150 mM NaCl, 100 μg/mL BSA and 50 % glycerol|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage Comment||Ship on gel ice. Store (in aliquots) at -20 °C to -70 °C.|
References for anti-CAMK2A Antibody (ABIN265086)Product Details anti-CAMK2A Antibody Target Details CAMK2A Application Details Handling Images back to top
Elgersma, Fedorov, Ikonen, Choi, Elgersma, Carvalho, Giese, Silva: "Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning." in: Neuron, Vol. 36, Issue 3, pp. 493-505, 2002
ImagesProduct Details anti-CAMK2A Antibody Target Details CAMK2A Application Details Handling References for anti-CAMK2A Antibody (ABIN265086) back to top