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|Antigen||Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) Antibodies|
|Reactivity||Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CAMK2D antibody is conjugated to HRP Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-CAMK2D AntibodyTarget Details CAMK2D Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human CAMK2D/CaMKII delta|
Target Details CAMK2DProduct Details anti-CAMK2D Antibody Application Details Handling Images back to top
|Alternative Name||CAMK2D (CAMK2D Antibody Abstract)|
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated å, â^, © and ∂, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but phosphorylation by a CaMK is also required for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.
Synonyms: Calcium / calmodulin dependent protein kinase 2 delta, Calcium / calmodulin dependent protein kinase II delta, Calcium/calmodulin-dependent protein kinase type II subunit delta, CAM kinase 2 delta, CAM kinase II delta, CaM kinase II subunit delta, CAMK 2d, CaMK-II subunit delta, CAMK2D, CAMKD, CAMKI, KCC2D_HUMAN, RATCAMKI.
|Pathways||WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration|
Application DetailsProduct Details anti-CAMK2D Antibody Target Details CAMK2D Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.|
|Precaution of Use||This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|