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|Antigen||Casein Kinase 1, alpha 1 (CSNK1A1) Antibodies|
|Epitope||AA 1-337, N-Term Alternatives|
|Conjugate||This CSNK1A1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-CSNK1A1 AntibodyTarget Details CSNK1A1 Application Details Handling References for anti-CSNK1A1 antibody (ABIN371879) Images
|Specificity||The antibody recognizes Human Casein Kinase 1 alpha. Other species not tested.|
|Characteristics||Synonyms: CKI-alpha, CSNK1A1, CK1|
|Purification||Protein-G affinity chromatography|
|Immunogen||Recombinant human Casein Kinase 1 alpha (1-337 aa) purified from E. coli|
Target Details CSNK1A1Product Details anti-CSNK1A1 Antibody Application Details Handling References for anti-CSNK1A1 antibody (ABIN371879) Images back to top
|Alternative Name||Casein Kinase I alpha (CSNK1A1 Antibody Abstract)|
|Background||Caseine Kinase 1 alpha belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. CK1 isoforms (alpha, beta, gamma, delta, epsilon) and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Perhaps it can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. Caseine kinase 1 alpha also interacts with the Axin complex.Synonyms: CK1, CKI-alpha, CSNK1A1|
|Pathways||WNT Signaling, Hedgehog Signaling|
Application DetailsProduct Details anti-CSNK1A1 Antibody Target Details CSNK1A1 Handling References for anti-CSNK1A1 antibody (ABIN371879) Images back to top
ELISA. Western blot (1: 1000 - 1: 2000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CSNK1A1 Antibody Target Details CSNK1A1 Application Details References for anti-CSNK1A1 antibody (ABIN371879) Images back to top
|Buffer||PBS, 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-CSNK1A1 antibody (ABIN371879)Product Details anti-CSNK1A1 Antibody Target Details CSNK1A1 Application Details Handling Images back to top
Katoh, Katoh: "WNT signaling pathway and stem cell signaling network." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 14, pp. 4042-5, 2007
Knippschild, Wolff, Giamas, Brockschmidt, Wittau, Würl, Eismann, Stöter: "The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development." in: Onkologie, Vol. 28, Issue 10, pp. 508-14, 2005
ImagesProduct Details anti-CSNK1A1 Antibody Target Details CSNK1A1 Application Details Handling References for anti-CSNK1A1 antibody (ABIN371879) back to top