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Browse our anti-CTNNB1 (CTNNB1) Antibodies

Full name:
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa Antibodies (CTNNB1)
On www.antibodies-online.com are 464 Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies from 25 different suppliers available. Additionally we are shipping CTNNB1 Kits (30) and CTNNB1 Proteins (23) and many more products for this protein. A total of 530 CTNNB1 products are currently listed.
Synonyms:
armadillo, beta-catenin, Bfc, Catnb, CHBCAT, ctnnb, ctnnb1, id:ibd2058, Jup, LOC100217813, Mesc, MRD19, wu:fb73e10, wu:fi81c06, wu:fk25h01
list all antibodies Gene Name GeneID UniProt
CTNNB1 12387 Q02248
CTNNB1 84353 Q9WU82
CTNNB1 1499 P35222

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Most Popular Reactivities for anti-CTNNB1 (CTNNB1) Antibodies

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anti-Mouse (Murine) CTNNB1 Antibodies:

anti-Rat (Rattus) CTNNB1 Antibodies:

anti-Human CTNNB1 Antibodies:

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Top referenced anti-CTNNB1 Antibodies

  1. Human Polyclonal CTNNB1 Primary Antibody for EIA, IF - ABIN951058 : Chairoungdua, Smith, Pochard, Hull, Caplan: Exosome release of ?-catenin: a novel mechanism that antagonizes Wnt signaling. in The Journal of cell biology 2010 (PubMed)
    Show all 4 references for ABIN951058

  2. Human Polyclonal CTNNB1 Primary Antibody for WB - ABIN783336 : Hülsken, Birchmeier, Behrens: E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. in The Journal of cell biology 1995 (PubMed)
    Show all 4 references for ABIN783336

  3. Hamster Monoclonal CTNNB1 Primary Antibody for FACS, IF - ABIN614788 : Valenta, Lukas, Korinek: HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. in Nucleic acids research 2003 (PubMed)
    Show all 3 references for ABIN614788

  4. Chicken Polyclonal CTNNB1 Primary Antibody for ChIP, WB - ABIN2792527 : Jiang, Tan, Li, Kivimäe, Yang, Zhuang, Lee, Chan, Stanton, Liu, Cheyette, Yu: DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. in Cancer cell 2008 (PubMed)

  5. Chicken Polyclonal CTNNB1 Primary Antibody for WB - ABIN2792526 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  6. Chicken Polyclonal CTNNB1 Primary Antibody for IHC (p), IP - ABIN181394 : Koslov, Maupin, Pradhan, Morrow, Rimm: Alpha-catenin can form asymmetric homodimeric complexes and/or heterodimeric complexes with beta-catenin. in The Journal of biological chemistry 1997 (PubMed)

  7. Human Polyclonal CTNNB1 Primary Antibody for IF, IHC (p) - ABIN655178 : Mirza, Sun, Zhao, Potula, Frey, Vogel, Malik, Zhao: FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression. in The Journal of experimental medicine 2010 (PubMed)

More Antibodies against CTNNB1 Interaction Partners

Horse (Equine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. temporal expression of CTNNB1 mRNA during dermal wound repair in the horse

Mouse (Murine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Wnt (show WNT2 Antibodies)/beta-catenin signaling pathway abnormalities possibly play an important role in the development of cognitive deficits among mice exposed to chronic intermittent hypoxia.

  2. Our findings highlight the critical roles of SIK1 (show SIK1 Antibodies) and its targets in the regulation of HCC (show FAM126A Antibodies) development and provides potential new candidates for HCC (show FAM126A Antibodies) therapy.

  3. PAX5 (show PAX5 Antibodies) was found to be an epigenetically inactivated tumor suppressor that inhibited non-small-cell lung proliferation and metastasis, through down-regulating the beta-catenin pathway and up-regulating GADD45G (show GADD45G Antibodies) expression.

  4. Data show athat beta-catenin can be activated by bone morphogenetic protein 9 (BMP9 (show GDF2 Antibodies)) and the activation of beta-catenin plays an important role in the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells induced by BMP9 (show GDF2 Antibodies).

  5. STAT3 (show STAT3 Antibodies)/Arid1b (show ARID1B Antibodies)/beta-catenin pathway is driving neurofibroma initiation.

  6. stabilization of b-catenin in cholangiocyte precursors perturbed duct development and cholangiocyte differentiation. We conclude that b-catenin is dispensable for biliary development but that its activity must be kept within tight limits.

  7. Our study contributes to the understanding of the role of HIF1alpha (show HIF1A Antibodies) in OA and highlights the HIF1alpha (show HIF1A Antibodies)-beta-catenin interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  8. To test the tumorigenic potential of different cell types in the developing kidney, we used kidney progenitor-specific Cre recombinase alleles to introduce Wt1 and Ctnnb1 mutations, two alterations observed in Wilms tumor, into embryonic mouse kidney, with and without biallelic Igf2 expression, another alteration that is observed in a majority of tumors

  9. These data highlight the ability of PTH (show PTH Antibodies) to phosphorylate beta-catenin directly via PKA.

  10. a conserved pro-fibrotic signal cascade might underlie beta-catenin-mediated bone marrow fibrosis.

Zebrafish Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.

  2. Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 Antibodies) pathway, therefore suggesting a possible role for Wnt (show WNT2 Antibodies) signalling during zebrafish tooth development and replacement.

  3. Findings suggest that microRNA 19b (miR (show MYLIP Antibodies)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.

  4. Custos binds to beta-catenin in a Wnt (show WNT2 Antibodies) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

  5. The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.

  6. The Wnt (show WNT2 Antibodies)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)

  7. This study demonstrated that beta-catenin/Wnt (show WNT2 Antibodies) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (show WNT2 Antibodies) signaling subsequently controls the fate of the progeny of those cell divisions.

  8. A novel role for Eaf1 (show EAF1 Antibodies) and Eaf2 (show EAF2 Antibodies) in inhibiting canonical Wnt (show WNT2 Antibodies)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 (show EAF1 Antibodies) and Eaf2 (show EAF2 Antibodies) tumor suppressor activity.

  9. Ccr7 (show CCR7 Antibodies) functions during axis formation as a GPCR (show GPRC6A Antibodies) to inhibit beta-catenin, likely by promoting Ca(2 (show CA2 Antibodies)+) transients throughout the blastula.

  10. ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.

Xenopus laevis Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. maternal Wnt (show WNT2 Antibodies)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression

  2. Custos binds to beta-catenin in a Wnt (show WNT2 Antibodies) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

  3. Wnt (show WNT2 Antibodies) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC Antibodies), Axin (show AXIN1 Antibodies) and GSK3 (show GSK3b Antibodies), although they are in general beta-catenin antagonising proteins.

  4. Phosphoinositide 3-kinase and Rac (show AKT1 Antibodies) polarization depend specifically on the N-cadherin (show CDH2 Antibodies)-p120 catenin (show CTNND1 Antibodies) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 Antibodies)-beta-catenin complex.

  5. HERG (show KCNH2 Antibodies) channel activity is stimulated by beta-catenin

  6. Zic3 (show ZIC3 Antibodies) can suppress Wnt (show WNT2 Antibodies)/beta-catenin signaling and control development of the notochord and Spemann's organizer.

  7. Notch (show NOTCH1 Antibodies) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (show GSK3b Antibodies)

  8. The tyrosine kinase receptor (show KDR Antibodies), PTK7 (show PTK7 Antibodies), is implicated in beta-catenin-dependent developmental processes.

  9. Kazrin (show KAZ Antibodies) interacts with ARVCF (show ARVCF Antibodies)-catenin, spectrin and p190B (show ARHGAP5 Antibodies) RhoGAP (show ARHGAP1 Antibodies), and modulates RhoA (show RHOA Antibodies) activity.

  10. Activated Xenopus CTNNB1 regulates embryonic limb development via FGF signaling

Human Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Results are the first to describe the presence of Wnt (show WNT2 Antibodies) signaling pathway abnormalities, manifested by nuclear beta-catenin, in a subset, as well as the lack of BRAF (show BRAF Antibodies)(V600E) mutation in gliosarcoma.

  2. Reduced expression of Wif-1 (show WIF1 Antibodies) and increased expression of beta-catenin may be involved in the pathogenesis of childhood acute lymphoblastic leukemia (ALL).

  3. A considerable number of TNBC co-expresses E-cadherin (show CDH1 Antibodies) and P-cadherin, while membranous localization of beta-catenin may predict patient outcome in an EGFR (show EGFR Antibodies)-dependent manner. This novel interaction seems worthy for validating with regards to its biological and clinical relevance

  4. our mutation analysis detected already known mutations as well as, to the best of our knowledge, mutations and an interstitial deletion of CTNNB1 not described in JAs (show TAP2 Antibodies) before. Additionally, a so far unknown transcribed Axin2 (show AXIN2 Antibodies) splice variant was found, but no further Axin2 (show AXIN2 Antibodies) mutations

  5. this is the first demonstration of a role for the leupaxin (show LPXN Antibodies) in the regulation of hepatocellular carcinoma progression, at least in part, by enhancing beta-catenin transcription activity.

  6. an activating mutation in CTNNB1 (S33F) was found in one colorectal tumor sample and immunohistochemical staining showed the accumulation of beta-catenin protein both in cytoplasm and in the nuclei of cancer cells as compared to normal tissue

  7. Reduced expression of beta-catenin expression in cell membrane is associated with esophageal carcinoma.

  8. Gene alterations in TERT (show TERT Antibodies) promoter, TP53 (show TP53 Antibodies), CTNNB1, and hepatitis B virus integration were closely associated with hepatocellular carcinoma development

  9. Taken together, these data suggest that SOX1 (show SOX1 Antibodies) can function as a tumor suppressor partly by interfering with Wnt (show WNT2 Antibodies)/beta-catenin signaling in breast cancer.

  10. beta-Catenin seems to be involved in the regulation of gelsolin (show GSN Antibodies) expression, which in turn affects the migratory ability of colonic cancer cells

Pig (Porcine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.

  2. beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.

  3. Wnt3a (show WNT3A Antibodies) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.

  4. beta-catenin controls myocardin (show MYOCD Antibodies)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes

  5. beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 Antibodies)-induced myofibroblast differentiation in aortic valve interstitial cells.

  6. scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin

  7. Data show that Wnt3a (show WNT3A Antibodies) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 Antibodies)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.

  8. TNF-alpha (show TNF Antibodies) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.

Cow (Bovine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. These results demonstrate that activation of AKT (show AKT1 Antibodies) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.

  2. beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.

  3. These data demonstrate for the first time that FSH (show BRD2 Antibodies) regulates CTNNB1 protein and WNT2 (show WNT2 Antibodies) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 Antibodies) signaling in ovarian steroidogenesis and follicular growth of cattle.

  4. These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.

  5. that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 Antibodies) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.

  6. This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.

  7. TGF-beta3 (show TGFB3 Antibodies) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 Antibodies)/beta-catenin signaling and T-cell factor-induced gene transcription.

  8. cAMP/PKA regulation of GSK3beta (show GSK3b Antibodies)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.

Rabbit Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 Antibodies)/beta-catenin and Hedgehog (show SHH Antibodies) signaling

  2. These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.

CTNNB1 Antigen Profile

Antigen Summary

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with CTNNB1

  • catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1) antibody
  • catenin (cadherin-associated protein), beta 1, 88kDa (LOC100217813) antibody
  • catenin (cadherin associated protein), beta 1 (Ctnnb1) antibody
  • catenin (cadherin-associated protein), beta 1 (ctnnb1) antibody
  • catenin (cadherin-associated protein), beta 1, 88kDa (ctnnb1-a) antibody
  • catenin (cadherin-associated protein), beta 1, 88kDa (ctnnb1-b) antibody
  • catenin (cadherin-associated protein), beta 1, 88kDa (Ctnnb1) antibody
  • armadillo antibody
  • beta-catenin antibody
  • Bfc antibody
  • Catnb antibody
  • CHBCAT antibody
  • ctnnb antibody
  • ctnnb1 antibody
  • id:ibd2058 antibody
  • Jup antibody
  • LOC100217813 antibody
  • Mesc antibody
  • MRD19 antibody
  • wu:fb73e10 antibody
  • wu:fi81c06 antibody
  • wu:fk25h01 antibody

Protein level used designations for CTNNB1

catenin beta 1 subunit , catenin beta-1 , beta catenin 1 , catenin (cadherin-associated protein), beta 1, 88kDa , catenin beta-1-like , beta-catenin , catenin (cadherin associated protein), beta 1, 88kDa , catenin beta , beta catenin

GENE ID SPECIES
450183 Pan troglodytes
574265 Macaca mulatta
100055241 Equus caballus
100173739 Pongo abelii
100217813 Taeniopygia guttata
100294600 Ovis aries
100395047 Callithrix jacchus
100583002 Nomascus leucogenys
12387 Mus musculus
84353 Rattus norvegicus
30265 Danio rerio
380441 Xenopus laevis
395964 Gallus gallus
1499 Homo sapiens
397657 Sus scrofa
399274 Xenopus laevis
477032 Canis lupus familiaris
539003 Bos taurus
100125985 Oryctolagus cuniculus
100732604 Cavia porcellus
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