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anti-Hamster CTNNB1 antibody for Immunocytochemistry

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • Jup
  • LOC100217813
  • CTNNB1
  • CTNNB
  • Bfc
  • Catnb
  • Mesc
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • ctnnb1
  • CHBCAT
  • MRD19
  • armadillo
  • beta-catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin (cadherin associated protein), beta 1
  • catenin (cadherin-associated protein), beta 1
  • CTNNB1
  • LOC100217813
  • Ctnnb1
  • ctnnb1
  • ctnnb1-a
  • ctnnb1-b
Epitope
C-Term, AA 441-448
79
20
19
19
18
16
14
14
12
10
8
8
7
6
6
5
5
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Hamster
439
204
181
62
53
36
26
24
22
20
15
15
14
10
9
9
3
1
1
1
1
1
1
Host
Mouse
293
154
5
2
Clonality
Monoclonal
Conjugate
This CTNNB1 antibody is un-conjugated
14
11
8
7
6
6
4
4
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
404
143
108
106
103
72
69
30
16
13
8
8
4
3
3
2
1
1
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Catalog No. ABIN457419
$ 288.75
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN574434 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see EM-22
1 ABIN211079 ICC IP WB Rabbit IgG AA 29-49 Log in to see Polyclonal
1 ABIN2619644 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 1-19 Log in to see Polyclonal
1 ABIN1723571 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see EM-22

Top referenced anti-CTNNB1 antibody for Immunocytochemistry

Similar anti-CTNNB1 Antibodies

Application / Reactivity Mouse (Murine) Human
Chromatin Immunoprecipitation (ChIP) 3 Antibodies 3 Antibodies
ELISA 49 Antibodies 133 Antibodies
Enzyme Immunoassay (EIA) 11 Antibodies 13 Antibodies
Flow Cytometry (FACS) 14 Antibodies
Immunocytochemistry (ICC) 21 Antibodies
Immunofluorescence (IF) 44 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunohistochemistry (IHC) 50 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 79 Antibodies
Immunoprecipitation (IP) 52 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Simple Western (SimWes) 1 Antibodies
Western Blotting (WB) 188 Antibodies
ELISA (Capture) 1 Antibodies

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Epitope C-Term, AA 441-448
(79), (20), (19), (19), (18), (16), (14), (14), (12), (10), (8), (8), (7), (6), (6), (5), (5), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Hamster
(439), (204), (181), (62), (53), (36), (26), (24), (22), (20), (15), (15), (14), (10), (9), (9), (3), (1), (1), (1), (1), (1), (1)
Host Mouse
(293), (154), (5), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CTNNB1 antibody is un-conjugated
(14), (11), (8), (7), (6), (6), (4), (4), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(404), (143), (108), (106), (103), (72), (69), (30), (16), (13), (8), (8), (4), (3), (3), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN457419) Images
Specificity The antibody EM-22 reacts with C-terminal part of beta-catenin, an 88 kDa multifunctional protein involved both in cell adhesion and in activation of transcription.
Purification Purified from cell culture supernatant by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Immunogen Recombinant human beta-catenin
Clone EM-22
Isotype IgG1

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 Antibody (ABIN457419) Images back to top
Antigen
Alternative Name CTNB1 (CTNNB1 Antibody Abstract)
Background Beta-catenin is a multifunctional protein involved both in cell adhesion and in activation of transcription. Calcium-dependent intercellular adhesion transmembrane glycoprotein E-cadherin interacts by its cytoplasmic domain with reciprocally bound alpha, beta and gamma catenin. Beta-catenin links this complex through alpha-actinin to the cytoskeleton. Functional cadherin-catenin system is important for invasiveness of tumour cells. Beta-catenin level in cytoplasm is controlled by glycogen synthase kinase-3 beta. When activity of this kinase is blocked (e.g. by excessive stimulation of Wnt signaling pathway), hypophosphorylated stable form of beta-catenin accumulates in the cytoplasm, translocates to the nucleus and activates transcription of genes including those that are involved in cell cycle control. As a result, cell division and neoplastic transformation are promoted.
Pathways WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 Antibody (ABIN457419) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 Antibody (ABIN457419) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CTNNB1 Antibody (ABIN457419)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Background publications

Nowak, Madej, Dziegiel: "Expression of E-cadherin, beta-catenin and Ki-67 antigen and their reciprocal relationships in mammary adenocarcinomas in bitches." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 45, Issue 3, pp. 233-8, 2007

Jung, Chung, Kim, Kim, Heo, Ahn, Hwang, Kim, Lee, Kim, Kim, Chang: "Epstein-Barr virus, beta-catenin, and E-cadherin in gastric carcinomas." in: Journal of Korean medical science, Vol. 22, Issue 5, pp. 855-61, 2007

Valenta, Lukas, Korinek: "HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells." in: Nucleic acids research, Vol. 31, Issue 9, pp. 2369-80, 2003

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN457419) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (C-Term) (ABIN457419) Immunocytochemistry staining of beta-catenin in humancolon adenocarcinoma cell line H...
Western Blotting (WB) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (C-Term) (ABIN457419) Western blotting analysis of beta-catenin in murine 3T3 (A), C57 (B) and KW1 (C) cell...
Flow Cytometry (FACS) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (C-Term) (ABIN457419) Flow cytometry analysis (intracellular) of beta-catenin in human MCF-7 cell line by -...