anti-Human CTNNB1 antibody for Flow Cytometry

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • Jup
  • LOC100217813
  • CTNNB1
  • CTNNB
  • Bfc
  • Catnb
  • Mesc
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • ctnnb1
  • CHBCAT
  • MRD19
  • armadillo
  • beta-catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin (cadherin associated protein), beta 1
  • catenin (cadherin-associated protein), beta 1
  • CTNNB1
  • LOC100217813
  • Ctnnb1
  • ctnnb1
  • ctnnb1-a
  • ctnnb1-b
Reactivity
Hamster, Human, Mouse (Murine)
493
223
198
63
53
41
26
25
21
21
15
15
14
10
9
9
3
1
1
1
1
1
1
Host
Mouse
310
193
9
2
Clonality
Monoclonal
Conjugate
This CTNNB1 antibody is un-conjugated
14
11
8
8
7
6
4
4
4
4
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
443
154
126
123
113
111
69
31
16
13
8
8
4
4
3
3
2
2
1
Supplier
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Catalog No. ABIN614788
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.996978 ABIN4899451 CyTOF FACS IHC IP SimWes WB Goat IgG AA 2-781 Log in to see Polyclonal 10
13.996978 ABIN4896129 FACS Allophycocyanin Mouse IgG2a AA 2-781 Log in to see 196624 1
13.996978 ABIN1881239 FACS IF IHC WB Rabbit N-Term, AA 78-106 Log in to see Polyclonal 5
13.996978 ABIN1881238 FACS IF IHC WB Rabbit C-Term, AA 692-721 Log in to see Polyclonal 5
13.996978 ABIN969072 ICC FACS IHC ELISA WB Mouse IgG1 Log in to see 4D5 3
13.996978 ABIN457419 ICC FACS IP WB Mouse IgG1 C-Term, AA 441-448 Log in to see EM-22 3
13.996978 ABIN4899452 CyTOF FACS WB Mouse IgG2a AA 2-781 Log in to see 196624
13.996978 ABIN2454137 FACS WB Mouse IgG2a Log in to see 6E7
13.996978 ABIN2454138 FACS IF WB Mouse IgG1 Log in to see 12C1
13.996978 ABIN2454136 FACS IF IHC WB Mouse IgG2a Log in to see 1E10
13.996978 ABIN2454166 FACS IHC WB Mouse IgG2b Log in to see 6A3
13.996978 ABIN2454168 FACS WB Mouse IgG2a Log in to see 11H9
13.996978 ABIN2454167 FACS IF WB Mouse IgG2a Log in to see 8B5
13.996978 ABIN2454169 FACS IHC WB Mouse IgG2a Log in to see 1B11
13.996978 ABIN2454170 FACS IHC WB Mouse IgG2b Log in to see 9H2
13.996978 ABIN2454135 FACS IF WB Mouse IgG2a Log in to see 5D2
13.996978 ABIN4896131 FACS PE Mouse IgG2a AA 2-781 Log in to see 196624
13.996978 ABIN4896130 FACS Fluorescein Mouse IgG2a AA 2-781 Log in to see 196624
13.996978 ABIN4896133 FACS Alexa Fluor 647 Goat IgG AA 2-781 Log in to see Polyclonal
13.996978 ABIN4896132 FACS Alexa Fluor 488 Goat IgG AA 2-781 Log in to see Polyclonal

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Reactivity Hamster, Human, Mouse (Murine)
(493), (223), (198), (63), (53), (41), (26), (25), (21), (21), (15), (15), (14), (10), (9), (9), (3), (1), (1), (1), (1), (1), (1)
Host Mouse
(310), (193), (9), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CTNNB1 antibody is un-conjugated
(14), (11), (8), (8), (7), (6), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(443), (154), (126), (123), (113), (111), (69), (31), (16), (13), (8), (8), (4), (4), (3), (3), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN614788) Images
Specificity This antibody reacts with C-terminal part of beta-Catenin, an 88 kDa multifunctional protein involved both in cell adhesion and in activation of transcription.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Hamster.
Species reactivity (tested):Human.
Purification Protein-A Affinity Chromatography
Immunogen Recombinant human beta-catenin
Clone EM-22
Isotype IgG1

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 antibody (ABIN614788) Images back to top
Antigen
Alternative Name Catenin beta-1 (CTNNB1 Antibody Abstract)
Background Beta-catenin is a multifunctional protein involved both in cell adhesion and in activation of transcription. Calcium-dependent intercellular adhesion transmembrane glycoprotein E-cadherin interacts by its cytoplasmic domain with reciprocally bound alpha, beta and gamma catenin. Beta-catenin links this complex through alpha-actinin to the cytoskeleton. Functional cadherin-catenin system is important for invasiveness of tumour cells. Beta-catenin level in cytoplasm is controlled by glycogen synthase kinase-3 beta. When activity of this kinase is blocked (e.g. by excessive stimulation of Wnt signaling pathway), hypophosphorylated stable form of beta-catenin accumulates in the cytoplasm, translocates to the nucleus and activates transcription of genes including those that are involved in cell cycle control. As a result, cell division and neoplastic transformation are promoted.Synonyms: Beta-catenin, CTNNB, CTNNB1
Gene ID 1499
NCBI Accession NP_001091679
UniProt P35222
Research Area Signaling
Pathways WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 antibody (ABIN614788) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 antibody (ABIN614788) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.4, 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CTNNB1 antibody (ABIN614788)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Background publications

Nowak, Madej, Dziegiel: "Expression of E-cadherin, beta-catenin and Ki-67 antigen and their reciprocal relationships in mammary adenocarcinomas in bitches." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 45, Issue 3, pp. 233-8, 2007

Jung, Chung, Kim, Kim, Heo, Ahn, Hwang, Kim, Lee, Kim, Kim, Chang: "Epstein-Barr virus, beta-catenin, and E-cadherin in gastric carcinomas." in: Journal of Korean medical science, Vol. 22, Issue 5, pp. 855-61, 2007

Valenta, Lukas, Korinek: "HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells." in: Nucleic acids research, Vol. 31, Issue 9, pp. 2369-80, 2003

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN614788) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
Western Blotting (WB) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (Image 2)
Flow Cytometry (FACS) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (Image 3)