You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human CTNNB1 antibody for Immunohistochemistry

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • armadillo
  • beta-catenin
  • Bfc
  • Catnb
  • CHBCAT
  • CTNNB
  • ctnnb
  • CTNNB1
  • ctnnb1
  • id:ibd2058
  • Jup
  • LOC100217813
  • Mesc
  • MRD19
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
Reactivity
Human
445
109
96
28
21
13
13
6
5
4
4
2
1
1
1
Host
Mouse
316
153
2
2
Clonality
Monoclonal
Conjugate
This CTNNB1 antibody is un-conjugated
15
12
9
6
6
6
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
402
152
115
100
84
66
65
31
16
13
8
4
3
3
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN969072
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22536378 ABIN1881239 FACS IF IHC WB Rabbit N-Term, AA 78-106 Log in to see Polyclonal 5
0.22536378 ABIN1881238 FACS IF IHC WB Rabbit C-Term, AA 692-721 Log in to see Polyclonal 5
0.22536378 ABIN189298 ICC IF IHC (p) IP IHC WB Rabbit IgG N-Term Log in to see E247
0.22536378 ABIN2454169 FACS IHC WB Mouse IgG2a Log in to see 1B11
0.22536378 ABIN2454170 FACS IHC WB Mouse IgG2b Log in to see 9H2
0.22536378 ABIN1533705 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22536378 ABIN1870089 IF IHC WB Rabbit IgG pSer33 Log in to see Polyclonal
0.22536378 ABIN1870091 IHC WB Rabbit IgG pSer37 Log in to see Polyclonal
0.22536378 ABIN257186 IHC (p) IHC WB Rabbit IgG Ser37 Log in to see Polyclonal
0.22536378 ABIN2164055 IHC ELISA WB Rabbit IgG Tyr489 Log in to see Polyclonal
0.22536378 ABIN1978137 IHC (p) IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.22536378 ABIN2164054 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22536378 ABIN2160408 IF IHC WB Rabbit Ig Fraction C-Term Log in to see Polyclonal
0.22536378 ABIN1842941 ICC FACS IF IHC ELISA WB Mouse IgG1 Log in to see
0.22536378 ABIN3019833 IF IHC WB Rabbit pSer33 Log in to see Polyclonal
0.22536378 ABIN3019836 IHC WB Rabbit pSer37 Log in to see Polyclonal
0.22536378 ABIN1849332 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.22536378 ABIN1847544 IHC ELISA WB Rabbit Internal Region, pTyr489 Log in to see Polyclonal
0.0011307208 ABIN2792303 IHC WB Rabbit C-Term Log in to see Polyclonal 1
0.0011307208 ABIN202911 IHC WB Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-CTNNB1 antibody for Immunohistochemistry

Similar anti-CTNNB1 Antibodies

Application / Reactivity Human
Chromatin Immunoprecipitation (ChIP) 3 Antibodies
ELISA 145 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 13 Antibodies
Flow Cytometry (FACS) 65 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 30 Antibodies
Immunofluorescence (IF) 98 Antibodies
Immunohistochemistry (IHC) 116 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 80 Antibodies
Immunoprecipitation (IP) 62 Antibodies
Luminex Assay (LMNX) 8 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Reactivity Human
(445), (109), (96), (28), (21), (13), (13), (6), (5), (4), (4), (2), (1), (1), (1)
Host Mouse
(316), (153), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CTNNB1 antibody is un-conjugated
(15), (12), (9), (6), (6), (6), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(402), (152), (115), (100), (84), (66), (65), (31), (16), (13), (8), (4), (3), (3), (2), (1), (1), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN969072) Images
Purification Ascites
Immunogen Purified recombinant fragment of human CTNNB1 expressed in E. coli.
Clone 4D5
Isotype IgG1

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 Antibody (ABIN969072) Images back to top
Antigen
Alternative Name CTNNB1 (CTNNB1 Antibody Abstract)
Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
Molecular Weight 85 kDa
Gene ID 1499
HGNC 1499
Pathways WNT Signaling

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 Antibody (ABIN969072) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 Antibody (ABIN969072) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-CTNNB1 Antibody (ABIN969072)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Product cited in:

Bougatef, Ouerhani, Moussa, Kourda, Coulet, Colas, Lahely, Najjar, Ben Jilani, Benammar-Elgaaied, Soubrier, Marrakchi: "Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer." in: Cancer genetics and cytogenetics, Vol. 187, Issue 1, pp. 12-8, 2008

Guo, Liu, Yang, Zhang, Yao: "Relation among p130Cas, E-cadherin and beta-catenin expression, clinicopathologic significance and prognosis in human hepatocellular carcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 5, pp. 490-6, 2008

Background publications

Rubinfeld, Souza, Albert, Munemitsu, Polakis: "The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin." in: The Journal of biological chemistry, Vol. 270, Issue 10, pp. 5549-55, 1995

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN969072) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN969072) Figure 1: Flow cytometric analysis of A549 cells using CTNNB1 mouse mAb (green) and n...
Immunocytochemistry (ICC) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN969072) Figure 2: Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using ...
Immunohistochemistry (IHC) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN969072) Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues us...
Western Blotting (WB) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN969072) Figure 4: Western blot analysis using CTNNB1 mouse mAb against CTNNB1-hIgGFc transfec...