anti-Human CTNNB1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • Jup
  • LOC100217813
  • CTNNB1
  • CTNNB
  • Bfc
  • Catnb
  • Mesc
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • ctnnb1
  • CHBCAT
  • MRD19
  • armadillo
  • beta-catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin (cadherin associated protein), beta 1
  • catenin (cadherin-associated protein), beta 1
  • CTNNB1
  • LOC100217813
  • Ctnnb1
  • ctnnb1
  • ctnnb1-a
  • ctnnb1-b
Epitope
AA 653-681, C-Term
79
21
21
20
20
19
17
16
15
11
10
9
8
7
6
5
5
5
5
5
5
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
493
224
198
63
53
41
26
25
21
21
15
15
15
10
9
9
3
1
1
1
1
1
1
Host
Rabbit
309
194
9
2
Clonality
Polyclonal
Conjugate
This CTNNB1 antibody is un-conjugated
14
11
8
8
7
6
4
4
4
4
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
443
154
126
123
113
112
70
31
16
12
8
8
4
4
3
3
2
2
1
Supplier
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Catalog No. ABIN951058
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.676567 ABIN2450412 IHC (p) WB Rabbit IgG AA 43-62 Log in to see Polyclonal
13.676567 ABIN337082 IHC (p) IP ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
13.676567 ABIN498724 IF IHC (p) Rabbit pSer33 Log in to see Polyclonal
13.676567 ABIN498825 IHC (p) Rabbit pSer45, pThr41 Log in to see Polyclonal
13.676567 ABIN498725 IF IHC (p) WB Rabbit pSer37 Log in to see Polyclonal
13.676567 ABIN498824 IHC (p) Rabbit pSer33, pSer37, pThr41 Log in to see Polyclonal
13.676567 ABIN498604 IHC (p) WB Rabbit Log in to see Polyclonal
13.676567 ABIN498914 IHC (p) Rabbit Log in to see Polyclonal
13.676567 ABIN498603 IF IHC (p) WB Rabbit Log in to see Polyclonal
13.676567 ABIN364501 ICC IHC (p) IP WB Mouse IgG AA 758-771, C-Term Log in to see
13.676567 ABIN1998631 ELISA IF IF/ICC IHC (p) IP Rabbit IgG AA 1-781 Log in to see 021
1 ABIN655178 IF IHC (p) WB Rabbit Ig AA 646-673, C-Term Log in to see Polyclonal 1
1 ABIN126747 EIA IF IHC (p) IP WB Mouse IgG1 Exon 3 Log in to see 9G2
1 ABIN614788 FACS IF IHC (p) IP WB Mouse IgG1 Log in to see EM-22 3
1 ABIN126748 EIA IF IHC (p) IP WB Mouse IgG2b Core Log in to see 9G10
1 ABIN126744 EIA IF IHC (p) WB Mouse IgG1 AA 35-50 Log in to see 7A7
1 ABIN126743 EIA IF IHC (p) WB Mouse IgG1 AA 27-37 Log in to see 8-00E-004
1 ABIN126750 EIA IF IHC (p) IP WB Mouse IgG1 C-Term Log in to see 7D8
1 ABIN197444 IF IHC (p) WB Rabbit Ser33 Log in to see Polyclonal 5
1 ABIN197446 IF IHC (p) WB Rabbit Ser37 Log in to see Polyclonal 5

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Epitope AA 653-681, C-Term
(79), (21), (21), (20), (20), (19), (17), (16), (15), (11), (10), (9), (8), (7), (6), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(493), (224), (198), (63), (53), (41), (26), (25), (21), (21), (15), (15), (15), (10), (9), (9), (3), (1), (1), (1), (1), (1), (1)
Host Rabbit
(309), (194), (9), (2)
Clonality
Polyclonal
Conjugate This CTNNB1 antibody is un-conjugated
(14), (11), (8), (8), (7), (6), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(443), (154), (126), (123), (113), (112), (70), (31), (16), (12), (8), (8), (4), (4), (3), (3), (2), (2), (1)
Pubmed 4 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN951058) Images
Specificity This antibody recognizes Human Catenin beta-1 (C-term).
Purification Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 653-681 amino acids from the C-terminal region of Human Catenin beta-1. Genename: CTNNB1
Isotype Ig

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 antibody (ABIN951058) Images back to top
Antigen
Alternative Name Catenin beta-1 (CTNNB1 Antibody Abstract)
Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Beta-catenin, CTNNB, CTNNB1
Molecular Weight 85497 Da
Gene ID 1499
NCBI Accession NP_001091679
Research Area Signaling
Pathways WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 antibody (ABIN951058) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 antibody (ABIN951058) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freezing and thawing.

References for anti-CTNNB1 antibody (ABIN951058)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Product cited in:

Chairoungdua, Smith, Pochard, Hull, Caplan: "Exosome release of ?-catenin: a novel mechanism that antagonizes Wnt signaling." in: The Journal of cell biology, Vol. 190, Issue 6, pp. 1079-91, 2010

Guo, Shen, Liao, Lian, Wang: "NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 7, pp. 450-6, 2010

Mirza, Sun, Zhao, Potula, Frey, Vogel, Malik, Zhao: "FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression." in: The Journal of experimental medicine, Vol. 207, Issue 8, pp. 1675-85, 2010

Teng, Wang, Wang, Wang: "[Effect of siRNA-mediated beta-catenin gene on Wnt signal pathway in lung adenocarcinoma A549 cell]." in: Zhonghua yi xue za zhi, Vol. 90, Issue 14, pp. 988-92, 2010

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN951058) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 653-681), (C-Term) antibody (ABIN951058) Confocal immunofluorescent analysis of Catenin beta-1 Antibody (C-term) Cat.-No AP511...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 653-681), (C-Term) antibody (ABIN951058) Formalin fixed, paraffin embedded human stomach tissuem stained with Catenin beta-1 A...
Western Blotting (WB) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 653-681), (C-Term) antibody (ABIN951058) Western blot analysis of CTNB1 (arrow) using Catenin beta-1 Antibody (C-term) Cat.-No...