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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|ELISA||43 Antibodies||49 Antibodies|
|Enzyme Immunoassay (EIA)||9 Antibodies||11 Antibodies|
|Flow Cytometry (FACS)||16 Antibodies||14 Antibodies|
|Immunocytochemistry (ICC)||16 Antibodies||21 Antibodies|
|Immunofluorescence (IF)||41 Antibodies||44 Antibodies|
|Immunofluorescence (fixed cells) (IF/ICC)||2 Antibodies|
|Immunohistochemistry (IHC)||48 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||11 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||63 Antibodies|
|Immunoprecipitation (IP)||35 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Simple Western (SimWes)||1 Antibodies|
|Western Blotting (WB)||164 Antibodies|
|Chromatin Immunoprecipitation (ChIP)||3 Antibodies|
|Antigen||Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies|
|Epitope||AA 2-781 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CTNNB1 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Simple Western (SimWes), Western Blotting (WB)
|10 references available|
|Supplier||Log in to see|
Product Details anti-CTNNB1 AntibodyTarget Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN4899451) Images
|Specificity||Detects human, mouse and rat beta-Catenin in Western blots.|
|Sterility||0.2 μm filtered|
|Immunogen||E. coli-derived recombinant human beta-Catenin, Ala2-Leu781, Accession # P35222|
Target Details CTNNB1Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 Antibody (ABIN4899451) Images back to top
|Alternative Name||CTNNB1 (CTNNB1 Antibody Abstract)|
|Background||Alternative Names: bCatenin, beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88 kDa, catenin beta-1, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923|
|Pathways||WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2|
Application DetailsProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 Antibody (ABIN4899451) Images back to top
Western Blot 1 μg/mL
Simple Western 50 μg/mL
Immunohistochemistry 5-15 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Chromatin Immunoprecipitation (ChIP) 5 μg/5 x 10^6 cells
|Restrictions||For Research Use only|
HandlingProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 Antibody (ABIN4899451) Images back to top
|Reconstitution||Reconstitute at 0.2 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-CTNNB1 Antibody (ABIN4899451)Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
|Product cited in:||
Andersson-Sjöland, Karlsson, Rydell-Törmänen: "ROS-induced endothelial stress contributes to pulmonary fibrosis through pericytes and Wnt signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 206-17, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).
Mao, Kuta, Crespo-Enriquez, Whiting, Martin, Mulvaney, Irvine, Francis-West: "Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis." in: Nature communications, Vol. 7, pp. 11469, 2016 Method employed by authors: Immunolocalization (IL) (Sample species: Mouse (Murine)).
Yamamoto, Ehling, Kato, Kanai, van Lessen, Frye, Zeuschner, Nakayama, Vestweber, Adams: "Integrin β1 controls VE-cadherin localization and blood vessel stability." in: Nature communications, Vol. 6, pp. 6429, 2015 Method employed by authors: Immunoprecipitation (IP) (Sample species: Mouse (Murine)).
Maeda, Ono, Holmbeck, Li, Kilts, Kram, Noonan, Yoshioka, McNerny, Tantillo, Kohn, Lyons, Robey, Young: "WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling." in: The Journal of biological chemistry, Vol. 290, Issue 22, pp. 14004-18, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Tu, Delgado-Calle, Condon, Maycas, Zhang, Carlesso, Taketo, Burr, Plotkin, Bellido: "Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 5, pp. E478-86, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Steele, Harper, Macaulay, Morrell, Perez-Tamayo, Foy, Habas, Poole, Fitzgerald, Maguire: "Canonical Wnt signaling negatively regulates platelet function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 47, pp. 19836-41, 2009 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Hu, Dong, Fernandez-Ruiz, Shan, Kawa, Martínez-Ansó, Prieto, Qian: "Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma." in: Cancer research, Vol. 69, Issue 17, pp. 6951-9, 2009 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Zhang, Lee, Wang, Dong, Ko, Pelletier, Yao: "Mutational analysis of the FXNPXY motif within LDL receptor-related protein 1 (LRP1) reveals the functional importance of the tyrosine residues in cell growth regulation and signal transduction." in: The Biochemical journal, Vol. 409, Issue 1, pp. 53-64, 2007 Method employed by authors: Western Blotting (WB) (Sample species: Hamster).
Diarra, Stolina, Polzer, Zwerina, Ominsky, Dwyer, Korb, Smolen, Hoffmann, Scheinecker, van der Heide, Landewe, Lacey, Richards, Schett: "Dickkopf-1 is a master regulator of joint remodeling." in: Nature medicine, Vol. 13, Issue 2, pp. 156-63, 2007 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Sáenz-Morales, Escribese, Stamatakis, García-Martos, Alegre, Conde, Pérez-Sala, Mampaso, García-Bermejo: "Requirements for proximal tubule epithelial cell detachment in response to ischemia: role of oxidative stress." in: Experimental cell research, Vol. 312, Issue 19, pp. 3711-27, 2006 Method employed by authors: Immunocytochemistry (ICC) (Sample species: Rat (Rattus)).
ImagesProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN4899451) back to top