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Browse our CTNNB1 Proteins (CTNNB1)

Full name:
Catenin (Cadherin-Associated Protein), beta 1, 88kDa Proteins (CTNNB1)
On www.antibodies-online.com are 25 Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Proteins from 9 different suppliers available. Additionally we are shipping CTNNB1 Antibodies (455) and CTNNB1 Kits (34) and many more products for this protein. A total of 527 CTNNB1 products are currently listed.
Synonyms:
armadillo, beta-catenin, Bfc, Catnb, CHBCAT, ctnnb, ctnnb1, id:ibd2058, Jup, LOC100217813, Mesc, MRD19, wu:fb73e10, wu:fi81c06, wu:fk25h01
list all proteins Gene Name GeneID UniProt
CTNNB1 12387 Q02248
CTNNB1 84353 Q9WU82
CTNNB1 1499 P35222

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CTNNB1 Proteins (CTNNB1) by Origin

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Top referenced CTNNB1 Proteins

  1. Human CTNNB1 Protein expressed in Baculovirus infected Insect Cells - ABIN2004177 : Hülsken, Birchmeier, Behrens: E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. in The Journal of cell biology 1995 (PubMed)
    Show all 6 references for ABIN2004177

  2. Mouse (Murine) CTNNB1 Protein expressed in Baculovirus infected Insect Cells - ABIN2008021 : Butz, Kemler: Distinct cadherin-catenin complexes in Ca(2+)-dependent cell-cell adhesion. in FEBS letters 1995 (PubMed)
    Show all 5 references for ABIN2008021

  3. Human CTNNB1 Protein expressed in Wheat germ - ABIN1350670 : Bian, Bai, Chapin, Le Moellic, Dong, Caplan, Sigworth, Navaratnam: Interactions between ?-catenin and the HSlo potassium channel regulates HSlo surface expression. in PLoS ONE 2011 (PubMed)

More Proteins for CTNNB1 Interaction Partners

Horse (Equine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. temporal expression of CTNNB1 mRNA during dermal wound repair in the horse

Mouse (Murine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. lung myeloid cells are responsive to Lrp5 (show LRP5 Proteins)/beta-catenin signaling, leading to differentiation of an alveolar macrophage subtype that antagonizes the resolution of lung fibrosis.

  2. Vascular smooth muscle beta-catenin is required for formation of neointima after vascular injury.

  3. Fzd7 expressed by endothelial cells drives postnatal angiogenesis via activation of Dvl (show DVL1 Proteins)/beta-catenin signaling and can control the integrative interaction of Wnt (show WNT2 Proteins) and Notch (show NOTCH1 Proteins) signaling during postnatal angiogenesis.

  4. The data suggest that vitamin D and calcium signaling are necessary components of the epidermal response to wounding, likely by regulating stem cell activation through increased beta-catenin transcriptional activity.

  5. Data show that methyl gallate (MG) prevents beta-catenin degradation during 3T3-L1 adipocytes differentiation.

  6. the persistence of p-beta-catenin(Y489) is a durable marker of fibroblast activation in Bronchopulmonary dysplasia and may play an important role in BPD disease pathobiology.

  7. Activation of the EP3 (show PTGER3 Proteins) receptor facilitates sprouting angiogenesis through protein kinase A/beta (show SUCLA2 Proteins)-catenin/notch (show NOTCH1 Proteins) signaling.

  8. AT2R (show AGTR2 Proteins) inhibits adipogenic differentiation in mesenchymal stem cells. Moreover, this inhibitory effect is associated with Wnt10b (show WNT10B Proteins)/beta-catenin signaling.

  9. Beta-catenin signaling controls C4ST-1 (show CHST11 Proteins) gene expression through histone deacetylase (show HDAC1 Proteins).

  10. Data show that beta-catenin was increased in expression when Tbx1 (show TBX1 Proteins) was inactivated, suggesting that there may be a negative feedback loop between canonical Wnt (show WNT2 Proteins) and Tbx1 (show TBX1 Proteins).

Zebrafish Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.

  2. Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 Proteins) pathway, therefore suggesting a possible role for Wnt (show WNT2 Proteins) signalling during zebrafish tooth development and replacement.

  3. Findings suggest that microRNA 19b (miR (show MYLIP Proteins)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.

  4. Custos binds to beta-catenin in a Wnt (show WNT2 Proteins) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

  5. The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.

  6. The Wnt (show WNT2 Proteins)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)

  7. This study demonstrated that beta-catenin/Wnt (show WNT2 Proteins) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (show WNT2 Proteins) signaling subsequently controls the fate of the progeny of those cell divisions.

  8. A novel role for Eaf1 (show EAF1 Proteins) and Eaf2 (show EAF2 Proteins) in inhibiting canonical Wnt (show WNT2 Proteins)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 (show EAF1 Proteins) and Eaf2 (show EAF2 Proteins) tumor suppressor activity.

  9. Ccr7 (show CCR7 Proteins) functions during axis formation as a GPCR to inhibit beta-catenin, likely by promoting Ca(2 (show CA2 Proteins)+) transients throughout the blastula.

  10. ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.

Xenopus laevis Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A (show PPP2R2B Proteins) and thereby down-regulating the Wnt (show WNT2 Proteins)/beta-catenin signaling.

  2. maternal Wnt (show WNT2 Proteins)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression

  3. Custos binds to beta-catenin in a Wnt (show WNT2 Proteins) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

  4. Wnt (show WNT2 Proteins) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC Proteins), Axin (show AXIN1 Proteins) and GSK3, although they are in general beta-catenin antagonising proteins.

  5. Phosphoinositide 3-kinase and Rac (show AKT1 Proteins) polarization depend specifically on the N-cadherin (show CDH2 Proteins)-p120 catenin (show CTNND1 Proteins) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 Proteins)-beta-catenin complex.

  6. HERG (show KCNH2 Proteins) channel activity is stimulated by beta-catenin

  7. Zic3 (show ZIC3 Proteins) can suppress Wnt (show WNT2 Proteins)/beta-catenin signaling and control development of the notochord and Spemann's organizer.

  8. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3

  9. The tyrosine kinase receptor (show KDR Proteins), PTK7 (show PTK7 Proteins), is implicated in beta-catenin-dependent developmental processes.

  10. Kazrin (show KAZ Proteins) interacts with ARVCF (show ARVCF Proteins)-catenin, spectrin and p190B RhoGAP (show ARHGAP1 Proteins), and modulates RhoA (show RHOA Proteins) activity.

Human Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. The BC cells showed the coexpression of E- and P-cadherins, as well as release of the molecules b- and p120 (show HNRNPU Proteins)-catenins into the cytoplasm of tumor cells, which leads to the activation of intracellular mechanisms for changing the structure of the cytoskeleton and the level of proliferation

  2. Our findings indicate that MSK1 (show RPS6KA5 Proteins)/beta-catenin signaling serves as an escape survival signal upon PI3K (show PIK3CA Proteins) inhibition and provides a strong rationale for the combined use of PI3K (show PIK3CA Proteins) and MSK1 (show RPS6KA5 Proteins)/beta-catenin inhibition to induce lethal growth inhibition in human GBM cells.

  3. CTNNB1 mutation is associated with Adrenocortical Adenomas.

  4. Our data suggests that total cellular b-catenin levels decrease in the presence of secreted frizzled-related protein 1 (show SFRP1 Proteins) and Wnt inhibitory factor 1 (show WIF1 Proteins), and a significant increase in cell death after tyrosine kinase (show TXK Proteins) inhibitor treatment is observed. On the contrary, when secreted frizzled-related protein 1 (show SFRP1 Proteins) is suppressed, total b-catenin levels increase in the cell and the cells become resistant to tyrosine kinase (show TXK Proteins) inhibitors.

  5. Results indicate a mechanism of beta-arrestin1 in modulating epithelial-mesenchymal transition (EMT) and glycogen synthase kinase 3 beta (GSK-3beta)/beta-catenin signaling in prostate cancer, and suggest that assessment of beta-arrestin1 may provide a potential therapeutic target for prostate cancer.

  6. Cytoplasmic beta-catenin expression is an independent prognostic factor for conventional renal cell carcinoma (show MOK Proteins)

  7. our surprise, NRAGE (show MAGED1 Proteins) induces nuclear localization of beta-catenin and increases its DNA binding ability. Further studies reveal that NRAGE (show MAGED1 Proteins) leads to the modification of beta-catenin/Arm with O-linked beta-N-acetylglucosamine (O-GlcNAc (show OGT Proteins)), and failure of the association between beta-catenin/Arm and pygopus(pygo) protein, which is required for transcriptional activation of Wnt (show WNT2 Proteins) target genes. Therefore, our findings suggest a ...

  8. These findings indicate a novel role for zinc regulation in the PKCalpha (show PKCa Proteins)/beta-catenin pathway and explain an important mechanism for controlling of stem cell program in lung cancer cells.

  9. A long noncoding RNA, lnc-beta-Catm, elicits EZH2 (show EZH2 Proteins)-dependent beta-catenin stabilization and sustains liver cancer stem cells self-renewal.

  10. EVI1 (show MECOM Proteins) transcription is directly regulated by LEF1 (show LEF1 Proteins)/beta-catenin complex in myeloid blast crisis of chronic myeloid leukemia (show BCL11A Proteins). Loss of p53 (show TP53 Proteins) function as a key regulator for beta-catenin-EVI1 (show MECOM Proteins) in myeloid blast crisis of chronic myeloid leukemia (show BCL11A Proteins).

Pig (Porcine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.

  2. beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.

  3. Wnt3a (show WNT3A Proteins) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.

  4. beta-catenin controls myocardin-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes

  5. beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 Proteins)-induced myofibroblast differentiation in aortic valve interstitial cells.

  6. scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin

  7. Data show that Wnt3a (show WNT3A Proteins) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 Proteins)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.

  8. TNF-alpha (show TNF Proteins) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.

Cow (Bovine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.

  2. These results demonstrate that activation of AKT (show AKT1 Proteins) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.

  3. beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.

  4. These data demonstrate for the first time that FSH (show BRD2 Proteins) regulates CTNNB1 protein and WNT2 (show WNT2 Proteins) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 Proteins) signaling in ovarian steroidogenesis and follicular growth of cattle.

  5. These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.

  6. that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 Proteins) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.

  7. This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.

  8. TGF-beta3 (show TGFB3 Proteins) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 Proteins)/beta-catenin signaling and T-cell factor-induced gene transcription.

  9. cAMP/PKA regulation of GSK3beta/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.

Rabbit Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

  1. Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 Proteins)/beta-catenin and Hedgehog (show SHH Proteins) signaling

  2. These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.

CTNNB1 Protein Profile

Protein Summary

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with CTNNB1

  • catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1)
  • catenin (cadherin-associated protein), beta 1, 88kDa (LOC100217813)
  • catenin (cadherin associated protein), beta 1 (Ctnnb1)
  • catenin (cadherin-associated protein), beta 1 (ctnnb1)
  • catenin (cadherin-associated protein), beta 1, 88kDa (ctnnb1-a)
  • catenin (cadherin-associated protein), beta 1, 88kDa (ctnnb1-b)
  • catenin (cadherin-associated protein), beta 1, 88kDa (Ctnnb1)
  • armadillo protein
  • beta-catenin protein
  • Bfc protein
  • Catnb protein
  • CHBCAT protein
  • ctnnb protein
  • ctnnb1 protein
  • id:ibd2058 protein
  • Jup protein
  • LOC100217813 protein
  • Mesc protein
  • MRD19 protein
  • wu:fb73e10 protein
  • wu:fi81c06 protein
  • wu:fk25h01 protein

Protein level used designations for CTNNB1

catenin beta 1 subunit , catenin beta-1 , beta catenin 1 , catenin (cadherin-associated protein), beta 1, 88kDa , catenin beta-1-like , beta-catenin , catenin (cadherin associated protein), beta 1, 88kDa , catenin beta , beta catenin

GENE ID SPECIES
450183 Pan troglodytes
574265 Macaca mulatta
100055241 Equus caballus
100173739 Pongo abelii
100217813 Taeniopygia guttata
100294600 Ovis aries
100395047 Callithrix jacchus
100583002 Nomascus leucogenys
12387 Mus musculus
84353 Rattus norvegicus
30265 Danio rerio
380441 Xenopus laevis
395964 Gallus gallus
1499 Homo sapiens
397657 Sus scrofa
399274 Xenopus laevis
477032 Canis lupus familiaris
539003 Bos taurus
100125985 Oryctolagus cuniculus
100732604 Cavia porcellus
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