Browse our anti-DKK1 (DKK1) Antibodies

Full name:
anti-Dickkopf Homolog 1 (Xenopus Laevis) Antibodies (DKK1)
On are 220 Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies from 27 different suppliers available. Additionally we are shipping DKK1 Kits (74) and DKK1 Proteins (55) and many more products for this protein. A total of 371 DKK1 products are currently listed.
AI414495, CT34, dickkopf-1, Dickkopf1, dkk, DKK-1, dkk1, dkk1-A, mdkk-1, mSgy, SGY, SGY-1, SGY1, SK, Soggy, Xdkk-1, xdkk1
list all antibodies Gene Name GeneID UniProt
DKK1 13380 O54908
DKK1 22943 O94907
DKK1 293897  

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Most Popular Reactivities for anti-DKK1 (DKK1) Antibodies

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anti-Mouse (Murine) DKK1 Antibodies:

anti-Human DKK1 Antibodies:

anti-Rat (Rattus) DKK1 Antibodies:

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Top referenced anti-DKK1 Antibodies

  1. Dog (Canine) Polyclonal DKK1 Primary Antibody for IF (p), IHC (p) - ABIN678158 : Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. in PLoS ONE 2014 (PubMed)
    Show all 2 references for 678158

  2. Human Polyclonal DKK1 Primary Antibody for EIA, WB - ABIN951911 : Piters, Balemans, Nielsen, Andersen, Boudin, Brixen, Van Hul: Common genetic variation in the DKK1 gene is associated with hip axis length but not with bone mineral density and bone turnover markers in young adult men: results from the Odense Androgen Study. in Calcified tissue international 2010 (PubMed)
    Show all 2 references for 951911

  3. Human Polyclonal DKK1 Primary Antibody for EIA, IHC (p) - ABIN357076 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)
    Show all 2 references for 357076

  4. Human Monoclonal DKK1 Primary Antibody for ELISA, WB - ABIN969085 : Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. in Developmental cell 2008 (PubMed)
    Show all 2 references for 969085

  5. Human Polyclonal DKK1 Primary Antibody for IHC (p), WB - ABIN388360 : Yan, Wu, Chen, Diao, Lai, Huang, Chen, Yu, Gui, Tang, Cai: Developmental expression and function of DKKL1/Dkkl1 in humans and mice. in Reproductive biology and endocrinology : RB&E 2012 (PubMed)

  6. Human Polyclonal DKK1 Primary Antibody for WB - ABIN653551 : Bourhis, Tam, Franke, Bazan, Ernst, Hwang, Costa, Cochran, Hannoush: Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. in The Journal of biological chemistry 2010 (PubMed)

  7. Cow (Bovine) Polyclonal DKK1 Primary Antibody for WB - ABIN2773909 : Ai, Holmen, Van Hul, Williams, Warman: Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. in Molecular and cellular biology 2005 (PubMed)

  8. Dog (Canine) Polyclonal DKK1 Primary Antibody for WB - ABIN2785520 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  9. Human Polyclonal DKK1 Primary Antibody for ELISA, WB - ABIN185275 : Fedi, Bafico, Nieto Soria, Burgess, Miki, Bottaro, Kraus, Aaronson: Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. in The Journal of biological chemistry 1999 (PubMed)

More Antibodies against DKK1 Interaction Partners

Pig (Porcine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. DKK1 inhibits the WNT (show WNT2 Antibodies) signaling pathway and improves pig oocyte maturation.

  2. Association analysis showed that different genotypes of DKK1 were associated with loin muscle area.

Rabbit Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) and Hedgehog (show SHH Antibodies) signaling

Zebrafish Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. activation of the FGF signaling pathway induces the formation of a dorsal axis with a complete head structure through the expression of chd (show CHRD Antibodies) and subsequent maintenance of dkk1b expression levels.

  2. Kremen1 (show KREMEN1 Antibodies) modulates Wnt (show WNT2 Antibodies) activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium

  3. Neuromast size is controlled by a balance between growth-promoting Wnt (show WNT2 Antibodies) signaling activity in proliferation-competent cells and Wnt (show WNT2 Antibodies)-inhibiting Dkk activity produced by differentiated sensory cells.

  4. Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles on the surfaces of adult male zebrafish pectoral fins

  5. Data show that injury-dependent induction of Ascl1a (show ASCL1A Antibodies) suppressed expression of the Wnt (show WNT2 Antibodies) signaling inhibitor, Dkk, and induced expression of the Wnt (show WNT2 Antibodies) ligand, Wnt4a.

Mouse (Murine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Dkk1 promotes hematopoietic regeneration via direct effects on hematopoietic stem cells, decreasing the levels of mitochondrial reactive oxygen species and suppressing senescence, and via indirect effects on bone marrow endothelial cells, inducing EGF (show EGF Antibodies) secretion.

  2. Recombinant Dkk1 suppresses beta-catenin (show CTNNB1 Antibodies) target genes in myeloid-derived suppressor cells (MDSCs) from mice and humans and anti-Dkk1 loses its antitumor effects in mice lacking beta-catenin (show CTNNB1 Antibodies) in myeloid cells or after depletion of MDSCs, demonstrating that Dkk1 directly targets MDSCs.

  3. A negative feedback loop involving WNT6 (show WNT6 Antibodies) and DKK1 attenuates canonical WNT6 (show WNT6 Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling, thereby allowing teratocarcinoma cells to differentiate.

  4. Collectively, miR (show MLXIP Antibodies)-9 promotes osteoblast differentiation of mesenchymal stem cells by suppressing DKK1 gene expression.

  5. that Dkk1 negatively regulates BMP9 (show GDF2 Antibodies)-induced osteogenic differentiation.

  6. Disturbed oscillatory flow increases DKK1 expression. DKK1 knockdown attenuates OSS-induced monocyte adhesion and endothelial impairment. Genetic silencing of DKK1 limits atherogenesis in ApoE (show APOE Antibodies)-/- mice.

  7. Dickkopf1 receptor Kremen1 (show KREMEN1 Antibodies) is a bona fide dependence receptor, triggering cell death unless bound to its ligand.

  8. These results suggest that inhibiting Wnt (show WNT2 Antibodies) signaling in embryonic stem cells using DKK1 may promote mouse ESCs (show NR2E3 Antibodies) to differentiate into endoderm in vitro and in vivo

  9. These in vivo data support in vitro studies regarding the mechanism of HBM (show LRP5 Antibodies)-causing mutations, and imply that HBM LRP5 (show LRP5 Antibodies) receptors differ in their relative sensitivity to inhibition by SOST (show SOST Antibodies) and DKK1.

  10. The combination of Dkk-1 overexpression by Dex and hypoxia causes the necrotic osteocytic cell death.

Cow (Bovine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. The decreased expression of Dkk-1 in somatic cell nuclear transfer cotyledons that are prone to abnormal placentation suggests a role in cotyledon formation but the mechanism and regulatory control is yet to be revealed[DICKKOPF-1]

Human Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. CKAP4 (show CKAP4 Antibodies) has a role as a Dickkopf1 receptor and in pancreatic and lung tumor progression

  2. Expression of Cancer stem cells-associated DKK1 mRNA might be an unfavorable prognostic marker for patients with hepatocellular carcinoma.

  3. In chronic kidney disease, serum levels of the Wnt (show WNT2 Antibodies) inhibitors DKK1 and sclerostin (show SOST Antibodies) are unrelated, indicating different sites of origin and/ or different regulatory mechanisms. Sclerostin (show SOST Antibodies), as opposed to DKK1, may qualify as a biomarker of chronic kidney disease-mineral and bone and mineral disorder (CKD-MBD (show DPEP1 Antibodies)), particularly in dialysis patients.

  4. endogenous expression of the WNT (show WNT2 Antibodies) antagonists DKK1 and FRZB (show FRZB Antibodies) is necessary for multiple steps during chondrogenesis

  5. The expression level of DKK1 in serum was increased in breast cancer patients, suggesting that serum expression level of DKK1 could be a useful biomarker in breast cancer.

  6. Results show that the expression of DKK1 is elevated in human HBV-related hepatocellular carcinoma tissues.

  7. DKK-1 and PDCD5 (show PDCD5 Antibodies) can be independent predictors of overall survival in patients suffering from chondrosarcoma.

  8. In patients with hepatocellular carcinoma serum DKK1 level correlated with tumor size, consequently, patients with bigger tumors tend to have higher levels of DKK1.

  9. Our results indicate that DKK1 and SFRP1 (show SFRP1 Antibodies) may be potentially useful biomarkers for evaluating the beneficial effects of long-term exercise on physical fitness and metabolism as well as the prognosis of patients with cancer.

  10. Dickkopf-1 and sclerostin (show SOST Antibodies) were never correlated with each other or with bone turnover markers patients with Paget's disease of bone

Xenopus laevis Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. dkk1 preferentially induced the expression of POX2, suggesting that dkk1 works as a morphogen (show SHH Antibodies) to determine the different lineages.

  2. N1 is a novel signaling domain within the intact protein that is responsible for the potent effects of Dkk1 on the induction and patterning of the body axis and heart

  3. target Wnts of Dkk activity are maternal Wnt5a (show WNT5A Antibodies) and Wnt11, and that both Wnts are essential for canonical and non-canonical signaling

DKK1 Antigen Profile

Antigen Summary

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DKK1

  • dickkopf 1 homolog (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (dkk1) antibody
  • dickkopf protein (dickkopf) antibody
  • dickkopf 1b (dkk1b) antibody
  • dickkopf homolog 1 (Xenopus laevis) (Dkk1) antibody
  • dickkopf homolog 1 (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (Dkk1) antibody
  • dickkopf-like 1 (DKKL1) antibody
  • dickkopf-like 1 (Dkkl1) antibody
  • AI414495 antibody
  • CT34 antibody
  • dickkopf-1 antibody
  • Dickkopf1 antibody
  • dkk antibody
  • DKK-1 antibody
  • dkk1 antibody
  • dkk1-A antibody
  • mdkk-1 antibody
  • mSgy antibody
  • SGY antibody
  • SGY-1 antibody
  • SGY1 antibody
  • SK antibody
  • Soggy antibody
  • Xdkk-1 antibody
  • xdkk1 antibody

Protein level used designations for DKK1

dickkopf homolog 1 , dickkopf-like protein 1 , dickkopf-related protein 1 , dickkopf 1 homolog , dickkopf protein , Ci-dickkopf , dickkopf1 , dickkopf 1 , dickkopf-1 , dkk-1 , dickkopf related protein-1 , dickkopf-1 like , hDkk-1 , cancer/testis antigen 34 , protein soggy-1 , soggy , soggy-1 , soggy 1

450465 Pan troglodytes
702997 Macaca mulatta
100228789 Taeniopygia guttata
549037 Xenopus (Silurana) tropicalis
778575 Ciona intestinalis
780707 Ciona intestinalis
609600 Canis lupus familiaris
100157640 Sus scrofa
100009504 Oryctolagus cuniculus
101116876 Ovis aries
30197 Danio rerio
13380 Mus musculus
374156 Gallus gallus
504445 Bos taurus
22943 Homo sapiens
373592 Xenopus laevis
293897 Rattus norvegicus
100731485 Cavia porcellus
27120 Homo sapiens
50722 Mus musculus
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