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Browse our anti-DKK1 (DKK1) Antibodies

Full name:
anti-Dickkopf Homolog 1 (Xenopus Laevis) Antibodies (DKK1)
On are 212 Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies from 26 different suppliers available. Additionally we are shipping DKK1 Kits (74) and DKK1 Proteins (52) and many more products for this protein. A total of 360 DKK1 products are currently listed.
AI414495, CT34, dickkopf-1, Dickkopf1, dkk, DKK-1, dkk1, dkk1-A, mdkk-1, mSgy, SGY, SGY-1, SGY1, SK, Soggy, Xdkk-1, xdkk1
list all antibodies Gene Name GeneID UniProt
DKK1 13380 O54908
DKK1 22943 O94907
DKK1 293897  

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Most Popular Reactivities for anti-DKK1 (DKK1) Antibodies

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anti-Mouse (Murine) DKK1 Antibodies:

anti-Human DKK1 Antibodies:

anti-Rat (Rattus) DKK1 Antibodies:

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Top referenced anti-DKK1 Antibodies

  1. Human Polyclonal DKK1 Primary Antibody for EIA, WB - ABIN951911 : Piters, Balemans, Nielsen, Andersen, Boudin, Brixen, Van Hul: Common genetic variation in the DKK1 gene is associated with hip axis length but not with bone mineral density and bone turnover markers in young adult men: results from the Odense Androgen Study. in Calcified tissue international 2010 (PubMed)
    Show all 2 references for ABIN951911

  2. Human Monoclonal DKK1 Primary Antibody for ELISA, WB - ABIN969085 : Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. in Developmental cell 2008 (PubMed)
    Show all 2 references for ABIN969085

  3. Human Polyclonal DKK1 Primary Antibody for EIA, IHC (p) - ABIN357076 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)
    Show all 2 references for ABIN357076

  4. Dog (Canine) Polyclonal DKK1 Primary Antibody for IF (p), IHC (p) - ABIN678158 : Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. in PLoS ONE 2014 (PubMed)
    Show all 2 references for ABIN678158

  5. Human Polyclonal DKK1 Primary Antibody for WB - ABIN374460 : Fedi, Bafico, Nieto Soria, Burgess, Miki, Bottaro, Kraus, Aaronson: Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. in The Journal of biological chemistry 1999 (PubMed)

  6. Human Polyclonal DKK1 Primary Antibody for IHC (p), WB - ABIN388360 : Yan, Wu, Chen, Diao, Lai, Huang, Chen, Yu, Gui, Tang, Cai: Developmental expression and function of DKKL1/Dkkl1 in humans and mice. in Reproductive biology and endocrinology : RB&E 2012 (PubMed)

  7. Cow (Bovine) Polyclonal DKK1 Primary Antibody for WB - ABIN2773909 : Ai, Holmen, Van Hul, Williams, Warman: Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. in Molecular and cellular biology 2005 (PubMed)

  8. Human Polyclonal DKK1 Primary Antibody for WB - ABIN653551 : Bourhis, Tam, Franke, Bazan, Ernst, Hwang, Costa, Cochran, Hannoush: Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. in The Journal of biological chemistry 2010 (PubMed)

  9. Dog (Canine) Polyclonal DKK1 Primary Antibody for WB - ABIN2785520 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against DKK1 Interaction Partners

Pig (Porcine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. DKK1 inhibits the WNT (show WNT2 Antibodies) signaling pathway and improves pig oocyte maturation.

  2. Association analysis showed that different genotypes of DKK1 were associated with loin muscle area.

Rabbit Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) and Hedgehog (show SHH Antibodies) signaling

Zebrafish Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. activation of the FGF signaling pathway induces the formation of a dorsal axis with a complete head structure through the expression of chd (show CHRD Antibodies) and subsequent maintenance of dkk1b expression levels.

  2. Kremen1 (show KREMEN1 Antibodies) modulates Wnt (show WNT2 Antibodies) activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium

  3. Neuromast size is controlled by a balance between growth-promoting Wnt (show WNT2 Antibodies) signaling activity in proliferation-competent cells and Wnt (show WNT2 Antibodies)-inhibiting Dkk activity produced by differentiated sensory cells.

  4. Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles on the surfaces of adult male zebrafish pectoral fins

  5. Data show that injury-dependent induction of Ascl1a (show ASCL1A Antibodies) suppressed expression of the Wnt (show WNT2 Antibodies) signaling inhibitor, Dkk, and induced expression of the Wnt (show WNT2 Antibodies) ligand, Wnt4a.

Mouse (Murine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. A negative feedback loop involving WNT6 (show WNT6 Antibodies) and DKK1 attenuates canonical WNT6 (show WNT6 Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling, thereby allowing teratocarcinoma cells to differentiate.

  2. Collectively, miR (show MLXIP Antibodies)-9 promotes osteoblast differentiation of mesenchymal stem cells by suppressing DKK1 gene expression.

  3. that Dkk1 negatively regulates BMP9 (show GDF2 Antibodies)-induced osteogenic differentiation.

  4. Disturbed oscillatory flow increases DKK1 expression. DKK1 knockdown attenuates OSS-induced monocyte adhesion and endothelial impairment. Genetic silencing of DKK1 limits atherogenesis in ApoE (show APOE Antibodies)-/- mice.

  5. Dickkopf1 receptor Kremen1 (show KREMEN1 Antibodies) is a bona fide dependence receptor, triggering cell death unless bound to its ligand.

  6. These results suggest that inhibiting Wnt (show WNT2 Antibodies) signaling in embryonic stem cells using DKK1 may promote mouse ESCs (show NR2E3 Antibodies) to differentiate into endoderm in vitro and in vivo

  7. These in vivo data support in vitro studies regarding the mechanism of HBM (show LRP5 Antibodies)-causing mutations, and imply that HBM LRP5 (show LRP5 Antibodies) receptors differ in their relative sensitivity to inhibition by SOST (show SOST Antibodies) and DKK1.

  8. The combination of Dkk-1 overexpression by Dex and hypoxia causes the necrotic osteocytic cell death.

  9. platelet-derived Dickkopf-1 (Dkk1) as the major Wnt (show WNT2 Antibodies) antagonist contributing to the suppression of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling in AECs during acute lung inflammation.

  10. R-spondin 1 (show RSPO1 Antibodies)/dickkopf-1/beta-catenin (show CTNNB1 Antibodies) machinery is involved in testicular embryonic angiogenesis

Cow (Bovine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. The decreased expression of Dkk-1 in somatic cell nuclear transfer cotyledons that are prone to abnormal placentation suggests a role in cotyledon formation but the mechanism and regulatory control is yet to be revealed[DICKKOPF-1]

Human Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Results found miR (show MLXIP Antibodies)-203 and DKK1 to be expressed at differential levels in cisplatin-sensitive and -insensitive lung adenocarcinoma tissues; there was also a negative correlation between them.

  2. Serum levels of OPG (show TNFRSF11B Antibodies) and DKK-1 were measured in 97 rheumatoid arthritis patients who were treated according to a treat-to-target strategy (T2T) aimed at remission (DAS28<2.6).

  3. DKK1 can promote vasculogenic mimicry formation via induction of the expression of epithelial-mesenchymal transition and cancer stem-like cell-related proteins.

  4. Our study highlighted the high serum levels of DKK-1 and sclerostin (show SOST Antibodies) in T1DM children and their relationship with altered glycemic control

  5. DKK-1 may play a role in switching to new bone formation in ankylosing spondylitis progression.

  6. link between Fibulin-4 (show FBLN4 Antibodies) and the canonical Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway that may contribute to our understanding of the molecular mechanisms of OA

  7. our findings reveal a new regulatory mechanism for miR (show MLXIP Antibodies)-373-3p and suggest that miR (show MLXIP Antibodies)-373-3p might be a potential target in tongue squamous cell carcinoma therapy

  8. there is a SP1 (show PSG1 Antibodies) site in DKK1 promoter region; overexpression of SP1 (show PSG1 Antibodies) could increase DKK1 promoter activity in a dose dependent manner; and siRNA inhibition of SP1 (show PSG1 Antibodies) expression reduced DKK1 promoter activity and decreased the expression of DKK1 protein.

  9. After evaluating a panel of Wnt (show WNT2 Antibodies) activating and inhibiting molecules, authors show that primary human MSCs increase the expression of Dkk-1, an inhibitor of Wnt (show WNT2 Antibodies) signaling, into the extracellular environment following chemotherapy exposure in a p53 (show TP53 Antibodies)-dependent manner.

  10. this study shows that DKK1 regulates fibroblast-like synociocyte transformation

Xenopus laevis Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. dkk1 preferentially induced the expression of POX2, suggesting that dkk1 works as a morphogen (show SHH Antibodies) to determine the different lineages.

  2. N1 is a novel signaling domain within the intact protein that is responsible for the potent effects of Dkk1 on the induction and patterning of the body axis and heart

  3. target Wnts of Dkk activity are maternal Wnt5a (show WNT5A Antibodies) and Wnt11, and that both Wnts are essential for canonical and non-canonical signaling

DKK1 Antigen Profile

Antigen Summary

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DKK1

  • dickkopf 1 homolog (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (dkk1) antibody
  • dickkopf protein (dickkopf) antibody
  • dickkopf 1b (dkk1b) antibody
  • dickkopf homolog 1 (Xenopus laevis) (Dkk1) antibody
  • dickkopf homolog 1 (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (Dkk1) antibody
  • dickkopf-like 1 (DKKL1) antibody
  • dickkopf-like 1 (Dkkl1) antibody
  • AI414495 antibody
  • CT34 antibody
  • dickkopf-1 antibody
  • Dickkopf1 antibody
  • dkk antibody
  • DKK-1 antibody
  • dkk1 antibody
  • dkk1-A antibody
  • mdkk-1 antibody
  • mSgy antibody
  • SGY antibody
  • SGY-1 antibody
  • SGY1 antibody
  • SK antibody
  • Soggy antibody
  • Xdkk-1 antibody
  • xdkk1 antibody

Protein level used designations for DKK1

dickkopf homolog 1 , dickkopf-like protein 1 , dickkopf-related protein 1 , dickkopf 1 homolog , dickkopf protein , Ci-dickkopf , dickkopf1 , dickkopf 1 , dickkopf-1 , dkk-1 , dickkopf related protein-1 , dickkopf-1 like , hDkk-1 , cancer/testis antigen 34 , protein soggy-1 , soggy , soggy-1 , soggy 1

450465 Pan troglodytes
702997 Macaca mulatta
100228789 Taeniopygia guttata
549037 Xenopus (Silurana) tropicalis
778575 Ciona intestinalis
780707 Ciona intestinalis
609600 Canis lupus familiaris
100157640 Sus scrofa
100009504 Oryctolagus cuniculus
101116876 Ovis aries
30197 Danio rerio
13380 Mus musculus
374156 Gallus gallus
504445 Bos taurus
22943 Homo sapiens
373592 Xenopus laevis
293897 Rattus norvegicus
100731485 Cavia porcellus
27120 Homo sapiens
50722 Mus musculus
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