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Browse our anti-DKK1 (DKK1) Antibodies

Full name:
anti-Dickkopf Homolog 1 (Xenopus Laevis) Antibodies (DKK1)
On www.antibodies-online.com are 197 Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies from 24 different suppliers available. Additionally we are shipping DKK1 Kits (70) and DKK1 Proteins (50) and many more products for this protein. A total of 339 DKK1 products are currently listed.
Synonyms:
AI414495, CT34, dickkopf-1, Dickkopf1, dkk, DKK-1, dkk1, dkk1-A, mdkk-1, mSgy, SGY, SGY-1, SGY1, SK, Soggy, Xdkk-1, xdkk1
list all antibodies Gene Name GeneID UniProt
DKK1 13380 O54908
DKK1 22943 O94907
DKK1 293897  

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Most Popular Reactivities for anti-DKK1 (DKK1) Antibodies

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anti-Mouse (Murine) DKK1 Antibodies:

anti-Human DKK1 Antibodies:

anti-Rat (Rattus) DKK1 Antibodies:

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Top referenced anti-DKK1 Antibodies

  1. Human Polyclonal DKK1 Primary Antibody for EIA, WB - ABIN951911 : Piters, Balemans, Nielsen, Andersen, Boudin, Brixen, Van Hul: Common genetic variation in the DKK1 gene is associated with hip axis length but not with bone mineral density and bone turnover markers in young adult men: results from the Odense Androgen Study. in Calcified tissue international 2010 (PubMed)
    Show all 2 references for ABIN951911

  2. Dog (Canine) Polyclonal DKK1 Primary Antibody for IF (p), IHC (p) - ABIN678158 : Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. in PLoS ONE 2014 (PubMed)
    Show all 2 references for ABIN678158

  3. Human Monoclonal DKK1 Primary Antibody for ELISA, WB - ABIN969085 : Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. in Developmental cell 2008 (PubMed)
    Show all 2 references for ABIN969085

  4. Human Polyclonal DKK1 Primary Antibody for EIA, IHC (p) - ABIN357076 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)
    Show all 2 references for ABIN357076

  5. Human Polyclonal DKK1 Primary Antibody for WB - ABIN374460 : Fedi, Bafico, Nieto Soria, Burgess, Miki, Bottaro, Kraus, Aaronson: Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. in The Journal of biological chemistry 1999 (PubMed)

  6. Human Polyclonal DKK1 Primary Antibody for IHC (p), WB - ABIN388360 : Yan, Wu, Chen, Diao, Lai, Huang, Chen, Yu, Gui, Tang, Cai: Developmental expression and function of DKKL1/Dkkl1 in humans and mice. in Reproductive biology and endocrinology : RB&E 2012 (PubMed)

  7. Human Polyclonal DKK1 Primary Antibody for WB - ABIN653551 : Bourhis, Tam, Franke, Bazan, Ernst, Hwang, Costa, Cochran, Hannoush: Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. in The Journal of biological chemistry 2010 (PubMed)

  8. Chicken Polyclonal DKK1 Primary Antibody for WB - ABIN2773909 : Ai, Holmen, Van Hul, Williams, Warman: Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. in Molecular and cellular biology 2005 (PubMed)

  9. Human Polyclonal DKK1 Primary Antibody for WB - ABIN2785520 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against DKK1 Interaction Partners

Pig (Porcine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. DKK1 inhibits the WNT (show WNT2 Antibodies) signaling pathway and improves pig oocyte maturation.

  2. Association analysis showed that different genotypes of DKK1 were associated with loin muscle area.

Zebrafish Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Kremen1 (show KREMEN1 Antibodies) modulates Wnt (show WNT2 Antibodies) activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium

  2. Neuromast size is controlled by a balance between growth-promoting Wnt (show WNT2 Antibodies) signaling activity in proliferation-competent cells and Wnt (show WNT2 Antibodies)-inhibiting Dkk activity produced by differentiated sensory cells.

  3. Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles on the surfaces of adult male zebrafish pectoral fins

  4. Data show that injury-dependent induction of Ascl1a (show ASCL1A Antibodies) suppressed expression of the Wnt (show WNT2 Antibodies) signaling inhibitor, Dkk, and induced expression of the Wnt (show WNT2 Antibodies) ligand, Wnt4a.

Mouse (Murine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. Dickkopf1 receptor Kremen1 (show KREMEN1 Antibodies) is a bona fide dependence receptor, triggering cell death unless bound to its ligand.

  2. These results suggest that inhibiting Wnt (show WNT2 Antibodies) signaling in embryonic stem cells using DKK1 may promote mouse ESCs (show NR2E3 Antibodies) to differentiate into endoderm in vitro and in vivo

  3. These in vivo data support in vitro studies regarding the mechanism of HBM (show LRP5 Antibodies)-causing mutations, and imply that HBM LRP5 (show LRP5 Antibodies) receptors differ in their relative sensitivity to inhibition by SOST (show SOST Antibodies) and DKK1.

  4. The combination of Dkk-1 overexpression by Dex and hypoxia causes the necrotic osteocytic cell death.

  5. platelet-derived Dickkopf-1 (Dkk1) as the major Wnt (show WNT2 Antibodies) antagonist contributing to the suppression of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling in AECs during acute lung inflammation.

  6. R-spondin 1 (show RSPO1 Antibodies)/dickkopf-1/beta-catenin (show CTNNB1 Antibodies) machinery is involved in testicular embryonic angiogenesis

  7. When Dkk1(+/-) mice were crossed with Bmp2 (show BMP2 Antibodies)(c/c);Prx1 (show PRDX1 Antibodies)::cre mice, the offspring bearing both genetic alterations were unable to increase bone mass and heal fractures

  8. thyroid hormone (show PTH Antibodies)-induced changes in bone remodeling are associated with a divergent regulation of DKK1 and sclerostin (show SOST Antibodies)

  9. OTX2 (show OTX2 Antibodies) and DKK1 exhibit asymmetric expression in the anterior ventral endoderm during embryonic anterior-posterior axis formation.

  10. Data indicate that both Dickkopf-1 (DKK1) and sclerostin (SOST (show SOST Antibodies)) were downregulated in proteoglycan (show Vcan Antibodies)-induced spondylitis (PGISp)-affected mouse spines.

Cow (Bovine) Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. The decreased expression of Dkk-1 in somatic cell nuclear transfer cotyledons that are prone to abnormal placentation suggests a role in cotyledon formation but the mechanism and regulatory control is yet to be revealed[DICKKOPF-1]

Human Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. High serum DKK-1 levels may be associated with tumor progression and poor prognosis in bladder cancer and may be used as a potential biomarker to predict the prognosis of patients with bladder cancer

  2. miR (show MLXIP Antibodies)-152 blocked DKK1 transcriptional activity by binding to the 3'UTR (show UTS2R Antibodies) of DKK1 mRNA.

  3. Synovial fibroblasts from patients with very early rheumatoid arthritis expressed significantly higher levels of DKK1 compared to patients with resolving arthritis.

  4. DKK1 polymorphisms may correlate to baseline bone mineral density and serum beta-CTX (show CYP27A1 Antibodies) levels, but present a weak effect on the response to alendronate.

  5. Through expression of the WNT (show WNT2 Antibodies) inhibitor DKK1, latency competent cancer cells self-impose a slow-cycling state with broad downregulation of ULBP ligands for NK cells and evasion of NK-cell-mediated clearance.

  6. DKK1 is found to be regulated by NBAT1 in a PRC2 dependent manner, and is responsible for NBAT1's effects in inhibiting migration and invasion of breast cancer cells.

  7. DKK1 is associated with angiogenesis in the synovial fluid of patients with temporomandibular joint disorders

  8. AFP (show AFP Antibodies) remained the best single marker, and the combined use of AFP (show AFP Antibodies) with prothrombin (show F2 Antibodies) precursor or DKK-1 had the best diagnostic performance compared to all other possible combinations of the four biomarkers, even in early stage hepatocellular carcinoma.

  9. Data indicate that in rheumatoid arthritis patients, level of receptor activator of nuclear factor-kappaB ligand (RANKL (show TNFSF11 Antibodies)) on T cells is elevated, and the serum level of RANKL (show TNFSF11 Antibodies) increases, but Dickkopf1 protein (DKK1) decreases.

  10. SOST (show SOST Antibodies) and DKK1 have opposing effects on PC3 (show PCSK1 Antibodies) cell invasion and bone-derived Wnt (show WNT2 Antibodies) signaling positively contributes to the invasive phenotypes of PC3 (show PCSK1 Antibodies)

Xenopus laevis Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) interaction partners

  1. dkk1 preferentially induced the expression of POX2, suggesting that dkk1 works as a morphogen (show SHH Antibodies) to determine the different lineages.

  2. N1 is a novel signaling domain within the intact protein that is responsible for the potent effects of Dkk1 on the induction and patterning of the body axis and heart

  3. target Wnts of Dkk activity are maternal Wnt5a (show WNT5A Antibodies) and Wnt11, and that both Wnts are essential for canonical and non-canonical signaling

DKK1 Antigen Profile

Antigen Summary

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DKK1

  • dickkopf 1 homolog (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (dkk1) antibody
  • dickkopf protein (dickkopf) antibody
  • dickkopf 1b (dkk1b) antibody
  • dickkopf homolog 1 (Xenopus laevis) (Dkk1) antibody
  • dickkopf homolog 1 (Xenopus laevis) (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (DKK1) antibody
  • dickkopf WNT signaling pathway inhibitor 1 (Dkk1) antibody
  • dickkopf-like 1 (DKKL1) antibody
  • dickkopf-like 1 (Dkkl1) antibody
  • AI414495 antibody
  • CT34 antibody
  • dickkopf-1 antibody
  • Dickkopf1 antibody
  • dkk antibody
  • DKK-1 antibody
  • dkk1 antibody
  • dkk1-A antibody
  • mdkk-1 antibody
  • mSgy antibody
  • SGY antibody
  • SGY-1 antibody
  • SGY1 antibody
  • SK antibody
  • Soggy antibody
  • Xdkk-1 antibody
  • xdkk1 antibody

Protein level used designations for DKK1

dickkopf homolog 1 , dickkopf-like protein 1 , dickkopf-related protein 1 , dickkopf 1 homolog , dickkopf protein , Ci-dickkopf , dickkopf1 , dickkopf 1 , dickkopf-1 , dkk-1 , dickkopf related protein-1 , dickkopf-1 like , hDkk-1 , cancer/testis antigen 34 , protein soggy-1 , soggy , soggy-1 , soggy 1

GENE ID SPECIES
450465 Pan troglodytes
702997 Macaca mulatta
100228789 Taeniopygia guttata
549037 Xenopus (Silurana) tropicalis
778575 Ciona intestinalis
780707 Ciona intestinalis
609600 Canis lupus familiaris
100157640 Sus scrofa
100009504 Oryctolagus cuniculus
101116876 Ovis aries
30197 Danio rerio
13380 Mus musculus
374156 Gallus gallus
504445 Bos taurus
22943 Homo sapiens
373592 Xenopus laevis
293897 Rattus norvegicus
100731485 Cavia porcellus
27120 Homo sapiens
50722 Mus musculus
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