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|Antigen||Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This DKK1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-DKK1 AntibodyTarget Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN357076) Images
|Specificity||This antibody detects DKKL1 at C-term.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DKKL1.|
Target Details DKK1Product Details anti-DKK1 Antibody Application Details Handling References for anti-DKK1 antibody (ABIN357076) Images back to top
|Alternative Name||Dickkopf-Like Protein 1 (DKK1 Antibody Abstract)|
|Background||The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has high similarity to the N-terminus of the dickkopf-3 protein and moderate similarity to that protein's C-terminus though the C-terminal cysteine residues are not conserved.Synonyms: CT34, Cancer/testis antigen 34, DKKL1, Protein soggy-1, SGY1|
|Molecular Weight||27007 Da|
|Gene ID||27120, 9606|
|Pathways||WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation|
Application DetailsProduct Details anti-DKK1 Antibody Target Details DKK1 Handling References for anti-DKK1 antibody (ABIN357076) Images back to top
ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details References for anti-DKK1 antibody (ABIN357076) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-DKK1 antibody (ABIN357076)Product Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling Images back to top
Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003
Krupnik, Sharp, Jiang, Robison, Chickering, Amaravadi, Brown, Guyot, Mays, Leiby, Chang, Duong, Goodearl, Gearing, Sokol, McCarthy: "Functional and structural diversity of the human Dickkopf gene family." in: Gene, Vol. 238, Issue 2, pp. 301-13, 1999
ImagesProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN357076) back to top