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anti-Rat (Rattus) DVL1 Antibodies:
anti-Human DVL1 Antibodies:
anti-Mouse (Murine) DVL1 Antibodies:
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Human Polyclonal DVL1 Primary Antibody for IHC (p), WB - ABIN4268104
Jung, Lee, Kim, Dhong, Cho, Roh: Role of Wnt signaling pathway in progression of sinonasal inverted papilloma to squamous cell carcinoma. in American journal of rhinology & allergy 2015
Pig (Porcine) DVL1 Primary Antibody for ELISA, WB - ABIN1782135
Spate, Brown, Redel, Whitworth, Murphy, Prather: Dickkopf-related protein 1 inhibits the WNT signaling pathway and improves pig oocyte maturation. in PLoS ONE 2014
Human Polyclonal DVL1 Primary Antibody for IF (p), IHC (p) - ABIN670671
Hua, Xu, He, Jiang, Ye, Pan: Wnt4/?-catenin signaling pathway modulates balloon-injured carotid artery restenosis via disheveled-1. in International journal of clinical and experimental pathology 2015
Human Polyclonal DVL1 Primary Antibody for ELISA, WB - ABIN560673
Turashvili, Bouchal, Baumforth, Wei, Dziechciarkova, Ehrmann, Klein, Fridman, Skarda, Srovnal, Hajduch, Murray, Kolar: Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. in BMC cancer 2007
Different Dvl (show DVL2 Antibodies) proteins (Dvl1, Dvl2 (show DVL2 Antibodies), Dvl3 (show DVL3 Antibodies)) and the composition of dishevelled (show DVL2 Antibodies)-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 Antibodies) signaling in Xenopus gastrulation.
Authors conclude that the planar cell polarity (PCP (show PRCP Antibodies)) pathway contributes significantly to the motility and hence the invasiveness of glioblastoma multiforme (GBM) cells, and that Nrdp1 (show RNF41 Antibodies) acts as a negative regulator of PCP (show PRCP Antibodies) signaling by inhibiting Dvl (show DVL2 Antibodies) through a novel polyubiquitination mechanism.
The DEP (show ZDHHC21 Antibodies) domain of Dishevelled (show DVL2 Antibodies) undergoes a conformational switch, from monomeric to swapped dimer, to trigger DIX domain-dependent polymerization and signaling to beta-catenin (show CTNNB1 Antibodies).
two mutually exclusive functions of the DEP (show ZDHHC21 Antibodies) domain in Wnt (show WNT2 Antibodies) signal transduction - binding to Frizzled to recruit Dishevelled (show DVL2 Antibodies) to the receptor complex, is reported.
we show that Wnt5a (show WNT5A Antibodies) rapidly represses rDNA gene transcription in breast cancer cells and generates a chromatin state with reduced transcription of rDNA by RNA polymerase I (show POLR1C Antibodies) (Pol I). These effects were specifically dependent on Dishevelled1 (DVL1), which accumulates in nucleolar organizer regions (NORs) and binds to rDNA regions of the chromosome.
Data show that dishevelled (show DVL2 Antibodies) proteins DVL1, 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).
The secreted frizzled-related protein (show SFRP2 Antibodies) and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors.
Data show that receptor for activated C kinase 1 (RACK1 (show GNB2L1 Antibodies)) interacts with Dishevelled (Dvl (show DVL2 Antibodies)) proteins and promotes their lysosomal degradation, and this effect is enhanced by autophagy induction.
TMEM88 stimulated triple negative breast cancer cell invasion by interacting with DVLl.
Specific -1 frameshift variants in the penultimate exon of DVL1 cause autosomal-dominant Robinow syndrome.
Results show that coexpression of IQGAP1 (show IQGAP1 Antibodies) and Dvl (show DVL2 Antibodies) in the cytoplasm and nucleus was correlated with the lymph nodal metastase and poor prognosis of non-small cell lung cancer.
Data show that the peptide binding pocket of the Dishevelled 1 (Dvl1) PDZ domain (show INADL Antibodies) is stabilized upon CXXC finger 5 protein (CXXC5 (show CXXC5 Antibodies)) binding.
Here we show that the peptide-binding pocket of the Dvl PDZ domain (show INADL Antibodies) can be occupied by Dvl's own highly conserved C-terminus, inducing a closed conformation.
The interaction of Dvl1 with Syt-1 (show SYT1 Antibodies), which is regulated by Wnts, modulates neurotransmitter release.
findings indicate that Dvl-1 may be an underlying participant of oxidative stress induced (show SQSTM1 Antibodies) by selenium deficiency
These results support a novel cell-autonomous postsynaptic role for Dact1 (show DACT1 Antibodies), in cooperation with Dishevelled-1 and possibly Disrupted in Schizophrenia-1 (show DISC1 Antibodies), in the formation of synapses on cortical interneuron dendrites.
we show that Dvl-1 expression is restricted to OSNs in the dorsal recess of the nasal cavity, and labels a unique subpopulation of glomeruli. Dvl-2 (show DVL2 Antibodies) and Dvl-3 (show DVL3 Antibodies) have a widespread distribution in both the olfactory epithelium and olfactory bulb .
Fuzzy appears to control subcellular localization of the core PCP (show BMP1 Antibodies) protein Dishevelled (show DVL2 Antibodies), recruiting it to Rab8 (show RAB8A Antibodies)-positive vesicles and to the basal body and cilium. We show that loss of Fuzzy results in inhibition of PCP (show BMP1 Antibodies) signaling
A Wnt5a (show WNT5A Antibodies)--> Dvl PCP (show BMP1 Antibodies) signaling cascade may regulate actin polymerization and protrusive cell behavior in the caudal (show CAD Antibodies) splanchnic mesoderm to promote second heart field deployment, outflow tract lengthening and cardiac looping.
Findings indicate that Daple (show CCDC88C Antibodies) interacts with Dishevelled (show DVL2 Antibodies) to direct the Dishevelled (show DVL2 Antibodies)/protein kinase (show CDK7 Antibodies) lambda protein complex to activate Rac (show AKT1 Antibodies), which in turn mediates the non-canonical Wnt (show WNT2 Antibodies) signalling pathway required for cell migration.
The antagonistic functions of Vangl2 (show VANGL2 Antibodies) and Dvl1 allow sharpening of planar cell polarity signaling locally on the tips of the filopodia to sense directional cues, Wnts, eventually causing turning of growth cones.
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
dishevelled, dsh homolog 1
, DSH homolog 1
, dishevelled 1
, segment polarity protein dishevelled homolog DVL-1
, dishevelled 1 (homologous to Drosophila dsh)
, dishevelled, dsh homolog 2, like