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anti-Mouse (Murine) FZD4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FZD4 Antibody (supplied by: Log in to see )

Antigen
Frizzled Family Receptor 4 (FZD4) Antibodies
  • anon-WO0170980.10
  • anon-WO0170980.11
  • CD344
  • CG4626
  • DFz4
  • Dfz4
  • Dmel\\CG4626
  • Dm Fz4
  • EVR1
  • FEVR
  • frizzled4
  • FZ-4
  • Fz-4
  • fz1
  • fz4
  • Fz4
  • FZD4S
  • FzE4
  • GPCR
  • hFz4
  • zg01
Epitope
AA 190-222
33
16
15
12
8
7
4
3
3
3
2
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
108
56
43
4
3
3
2
2
2
2
2
2
1
1
1
Host
Rabbit
76
23
10
8
Clonality
Polyclonal
Conjugate
This FZD4 antibody is un-conjugated
7
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
53
13
13
12
12
10
3
2
1
1
Supplier
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Catalog No. ABIN1714167
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008973577 ABIN122078 IHC (p) Rabbit C-Term Log in to see Polyclonal
0.0008973577 ABIN1700665 IHC (p) WB Biotin Rabbit IgG AA 190-222 Log in to see Polyclonal
0.0008973577 ABIN1711682 IHC (p) WB HRP Rabbit IgG AA 190-222 Log in to see Polyclonal
0.0008973577 ABIN4312597 IHC (p) Rabbit C-Term Log in to see Polyclonal

Similar anti-FZD4 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 15 Antibodies 17 Antibodies 51 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 3 Antibodies
Immunofluorescence (IF) 9 Antibodies 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 5 Antibodies
Western Blotting (WB) 19 Antibodies 26 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunochromatography (IC) 2 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen Frizzled Family Receptor 4 (FZD4) Antibodies
Epitope AA 190-222
(33), (16), (15), (12), (8), (7), (4), (3), (3), (3), (2), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(108), (56), (43), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(76), (23), (10), (8)
Clonality
Polyclonal
Conjugate This FZD4 antibody is un-conjugated
(7), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(68), (53), (13), (13), (12), (12), (10), (3), (2), (1), (1)
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Product Details anti-FZD4 Antibody

Target Details FZD4 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Frizzled 4/CD344
Isotype IgG

Target Details FZD4

Product Details anti-FZD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Frizzled 4/CD344 (FZD4 Antibody Abstract)
Background

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP). In retina, it can be both activated by Wnt protein-binding, but also by a Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accumulation and stimulation of LEF/TCF-mediated transcriptional programs. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular location: Extracellular


Synonyms: Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, CD344, FZD4S, Frizzled-4, FZD4
Gene ID 8322
UniProt Q9ULV1
Pathways WNT Signaling

Application Details

Product Details anti-FZD4 Antibody Target Details FZD4 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FZD4 Antibody Target Details FZD4 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-FZD4 Antibody Target Details FZD4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FZD4 antibody (Frizzled Family Receptor 4) (AA 190-222) (ABIN1714167) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Frizzled 4/CD344 ...