anti-Human GPBAR1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended GPBAR1 Antibody (supplied by: Log in to see )

Antigen
G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) Antibodies
  • MGC84403
  • GPBAR1
  • CD344
  • EVR1
  • FEVR
  • FZD4S
  • Fz-4
  • Fz4
  • FzE4
  • GPCR
  • hFz4
  • BG37
  • GPCR19
  • GPR131
  • M-BAR
  • TGR5
  • Tgr5
  • Gpbar1
  • G protein-coupled bile acid receptor 1
  • frizzled family receptor 4
  • G protein-coupled receptor
  • gpbar1
  • GPBAR1
  • FZD4
  • Gpbar1
  • TGR5
Reactivity
Human
112
21
15
4
4
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
94
19
Clonality
Polyclonal
Conjugate
This GPBAR1 antibody is conjugated to Alexa Fluor 488
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
39
39
20
18
12
7
4
2
1
Options
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Catalog No. ABIN1694561
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1707408 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1709219 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1698202 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1692748 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN1696391 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1703639 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1701828 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN1705450 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN2808674 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN1713517 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN5003833 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal
1 ABIN5003834 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal

General

Antigen G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) Antibodies
Reactivity Human
(112), (21), (15), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(94), (19)
Clonality
Polyclonal
Conjugate This GPBAR1 antibody is conjugated to Alexa Fluor 488
(3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(39), (39), (20), (18), (12), (7), (4), (2), (1)
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Product Details anti-GPBAR1 Antibody

Target Details GPBAR1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human GPBAR1
Isotype IgG

Target Details GPBAR1

Product Details anti-GPBAR1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name GPBAR1 (GPBAR1 Antibody Abstract)
Background

The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

Subcellular location: Extracellular

Synonyms: BG 37, BG37, G protein coupled bile acid receptor 1, G protein coupled bile acid receptor BG 37, G protein coupled bile acid receptor BG37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GPBAR 1, GPBAR_HUMAN, GPBAR1, GPCR 19, GPCR, GPCR19, GPR 131, GPR131, hBG 37, hBG37, hGPCR 19, hGPCR19, M BAR, M-BAR, Membrane bile acid receptor, Membrane type receptor for bile acids, Membrane-type receptor for bile acids, MGC40597, TGR 5, TGR5.

Gene ID 151306
Pathways WNT Signaling, Hormone Transport, Sensory Perception of Sound

Application Details

Product Details anti-GPBAR1 Antibody Target Details GPBAR1 Handling Images back to top
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-GPBAR1 Antibody Target Details GPBAR1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months