anti-Human KREMEN1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended KREMEN1 Antibody (supplied by: Log in to see )

Antigen
Kringle Containing Transmembrane Protein 1 (KREMEN1) Antibodies
  • KREMEN1
  • krm1
  • kremen
  • kremem1
  • KREMEN
  • KRM1
  • AV002070
  • Kremen
  • Krm1
  • si:ct737139.1
  • si:dkeyp-7c9.1
  • kringle containing transmembrane protein 1
  • KREMEN1
  • kremen1
  • Kremen1
Epitope
N-Term
31
19
15
14
9
5
2
2
2
2
1
1
1
1
Reactivity
Human
73
34
14
4
4
3
3
2
2
2
1
1
1
1
Host
Rabbit
68
18
5
2
Clonality
Polyclonal
Conjugate
This KREMEN1 antibody is un-conjugated
7
7
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
75
55
33
17
5
5
2
2
1
1
1
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Catalog No. ABIN357077
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN768924 IHC (p) WB Rabbit AA 71-120 Log in to see Polyclonal
1 ABIN388361 IHC (p) WB Rabbit Ig AA 6-37, N-Term Log in to see Polyclonal
1 ABIN2963239 IF IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1908740 IF IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1840580 IHC (p) WB Rabbit AA 6-37 Log in to see Polyclonal

General

Antigen Kringle Containing Transmembrane Protein 1 (KREMEN1) Antibodies
Epitope N-Term
(31), (19), (15), (14), (9), (5), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(73), (34), (14), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(68), (18), (5), (2)
Clonality
Polyclonal
Conjugate This KREMEN1 antibody is un-conjugated
(7), (7), (6), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(75), (55), (33), (17), (5), (5), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-KREMEN1 Antibody

Target Details KREMEN1 Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) Images
Specificity This antibody detects Kremen at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen.
Isotype Ig

Target Details KREMEN1

Product Details anti-KREMEN1 Antibody Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) Images back to top
Antigen
Alternative Name Kremen Protein 1 (KREMEN1 Antibody Abstract)
Background Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose
Molecular Weight 63,201 Da
Gene ID 83999
NCBI Accession NP_001034659
UniProt Q96MU8
Pathways WNT Signaling

Application Details

Product Details anti-KREMEN1 Antibody Target Details KREMEN1 Handling References for anti-KREMEN1 antibody (ABIN357077) Images back to top
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details References for anti-KREMEN1 antibody (ABIN357077) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-KREMEN1 antibody (ABIN357077)

Product Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details Handling Images back to top
Background publications

Mao, Wu, Davidson, Marhold, Li, Mechler, Delius, Hoppe, Stannek, Walter, Glinka, Niehrs: "Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling." in: Nature, Vol. 417, Issue 6889, pp. 664-7, 2002

Kammeraat, Veldstra: "Characterization of succinate semialdehyde dehydrogenase from rat brain." in: Biochimica et biophysica acta, Vol. 151, Issue 1, pp. 1-10, 1970

Images

Product Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) back to top
Supplier Images
 image for anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody (ABIN357077) anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody
 image for anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody (ABIN357077) anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody (Image 2)