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|Antigen||Kringle Containing Transmembrane Protein 1 (KREMEN1) Antibodies|
|Conjugate||This KREMEN1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|2 references available|
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Product Details anti-KREMEN1 AntibodyTarget Details KREMEN1 Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) Images
|Specificity||This antibody detects Kremen at N-term.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen.|
Target Details KREMEN1Product Details anti-KREMEN1 Antibody Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) Images back to top
|Alternative Name||Kremen Protein 1 (KREMEN1 Antibody Abstract)|
|Background||Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose|
|Molecular Weight||63,201 Da|
Application DetailsProduct Details anti-KREMEN1 Antibody Target Details KREMEN1 Handling References for anti-KREMEN1 antibody (ABIN357077) Images back to top
ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details References for anti-KREMEN1 antibody (ABIN357077) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-KREMEN1 antibody (ABIN357077)Product Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details Handling Images back to top
Mao, Wu, Davidson, Marhold, Li, Mechler, Delius, Hoppe, Stannek, Walter, Glinka, Niehrs: "Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling." in: Nature, Vol. 417, Issue 6889, pp. 664-7, 2002
Kammeraat, Veldstra: "Characterization of succinate semialdehyde dehydrogenase from rat brain." in: Biochimica et biophysica acta, Vol. 151, Issue 1, pp. 1-10, 1970
ImagesProduct Details anti-KREMEN1 Antibody Target Details KREMEN1 Application Details Handling References for anti-KREMEN1 antibody (ABIN357077) back to top