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Browse our anti-LLGL1 (LLGL1) Antibodies

Full name:
anti-Lethal Giant Larvae Homolog 1 (Drosophila) Antibodies (LLGL1)
On www.antibodies-online.com are 22 Lethal Giant Larvae Homolog 1 (Drosophila) (LLGL1) Antibodies from 9 different suppliers available. Additionally we are shipping LLGL1 Proteins (3) and many more products for this protein. A total of 27 LLGL1 products are currently listed.
Synonyms:
AI325176, DLG4, HUGL, HUGL-1, HUGL1, Lgl1, LLGL, LLGL1, Llglh, Mgl1, Rgl1
list all antibodies Gene Name GeneID UniProt
LLGL1 3996 Q15334
LLGL1 16897 Q80Y17
LLGL1 54265 Q8K4K5

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Most Popular Reactivities for anti-LLGL1 (LLGL1) Antibodies

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anti-Human LLGL1 Antibodies:

anti-Mouse (Murine) LLGL1 Antibodies:

anti-Rat (Rattus) LLGL1 Antibodies:

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Top referenced anti-LLGL1 Antibodies

  1. Human Polyclonal LLGL1 Primary Antibody for EIA, WB - ABIN357635 : Schimanski, Schmitz, Kashyap, Bosserhoff, Bataille, Schäfer, Lehr, Berger, Galle, Strand, Strand: Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer. in Oncogene 2005 (PubMed)
    Show all 3 references for ABIN357635

  2. Human Polyclonal LLGL1 Primary Antibody for WB - ABIN388988 : Grifoni, Garoia, Schimanski, Schmitz, Laurenti, Galle, Pession, Cavicchi, Strand: The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo. in Oncogene 2004 (PubMed)
    Show all 3 references for ABIN388988

  3. Human Monoclonal LLGL1 Primary Antibody for ELISA, WB - ABIN561683 : Russ, Louderbough, Zarnescu, Schroeder: Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation. in PLoS ONE 2012 (PubMed)

More Antibodies against LLGL1 Interaction Partners

Human Lethal Giant Larvae Homolog 1 (Drosophila) (LLGL1) interaction partners

  1. Reduced expression of Hugl 1 predicts poor survival in lung SqCC patients. The expression of Hugl 1 was inversely correlated with both overall survival rate and tumor stage.

  2. Our results support the growing appreciation that the tumour regulatory functions of Scribble (show SCRIB Antibodies), and other polarity protein family members, are context dependent.

  3. this study provides the evidence that Hugl-1 inhibits glioma cell growth in intracranial model of nude mice, suggesting that Hugl-1 might be a potential tumor target for glioma therapy.

  4. Lgl1 (show CRISPLD2 Antibodies) has a role in inhibiting glioblastoma

  5. PTEN (show PTEN Antibodies) loss leads to the phosphorylation and inactivation of Lgl by atypical protein kinase C (show PRKCZ Antibodies) in glioblastoma cells.

  6. Suggest that Hugl-1 induces growth suppression and apoptosis in a human esophageal squamous cell carcinoma cell line both in vitro and in vivo.

  7. inactivation of Llgl1 enhances hematopoietic stem cells self-renewal and fitness and is associated with unfavorable outcome in human acute myeloid leukemia (show BCL11A Antibodies)

  8. Hugl1 and Hugl2 play an essential role in the maintenance of breast epithelial polarity and differentiated cell morphology, as well as growth control.

  9. Preservation of HUGL-1 expression in pancreatic adenocarcinoma is a good prognostic factor that contributes to a better overall survival

  10. Hugl-1 can act as a tumour suppressor in Drosophila and thus is the functional homologue of lgl

Mouse (Murine) Lethal Giant Larvae Homolog 1 (Drosophila) (LLGL1) interaction partners

  1. Data indicate hyperproliferation, impaired differentiation and increased apoptosis of neural progenitors in the cerebellum of lethal giant larvae homolog 1 (Lgl1 (show Klra7 Antibodies))-Pax2 (show PAX2 Antibodies) protein knockout embryos.

  2. Lgl1 (show Klra7 Antibodies) forms two distinct complexes in vivo, Lgl1 (show Klra7 Antibodies)-NMIIA and Lgl1 (show Klra7 Antibodies)-Par6alpha (show PARD6A Antibodies)-aPKCzeta (show PRKCZ Antibodies), and that the formation of these complexes is affected by the phosphorylation state of Lgl1 (show Klra7 Antibodies).

  3. Collectively these findings indicate that Lgl1 (show Klra7 Antibodies) regulates the polarity of migrating cells by controlling the assembly state of NMII-A, its cellular localization, and focal adhesion assembly.

  4. This is the first study to demonstrate the involvement of Dlg1 (show DLG1 Antibodies), Scrib (show SCRIB Antibodies), and Lgl1 (show Klra7 Antibodies) in a mouse with ocular adenocarcinoma and the simultaneous involvement of these proteins in the same cancer.

  5. Findings reveal that RanBPM plays a novel role in regulating Mgl-1 stability and contributes to its biological function as a tumor suppressor.

  6. mgl-1 mRNA is developmentally expressed in CNS, craniofacial region, eyes, limbs, and the gut (show GUSB Antibodies)

  7. results reveal a critical role for mammalian Lgl1 (show Klra7 Antibodies) in regulating of proliferation, differentiation, and tissue organization and demonstrate a potential causative role of disruption of cell polarity in neoplastic transformation of neuroepithelial cells.

  8. Early branching morphogenesis in the lung and kidney is stimulated by retinoic acid, and retinoic acid response elements in the Lgl1 (show Klra7 Antibodies) promoter are identified.

LLGL1 Antigen Profile

Antigen Summary

This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Alternative names and synonyms associated with LLGL1

  • discs, large homolog 4 (Drosophila) (DLG4) antibody
  • lethal giant larvae homolog 1 (Drosophila) (LLGL1) antibody
  • lethal giant larvae homolog 1 (Drosophila) (Llgl1) antibody
  • AI325176 antibody
  • DLG4 antibody
  • HUGL antibody
  • HUGL-1 antibody
  • HUGL1 antibody
  • Lgl1 antibody
  • LLGL antibody
  • LLGL1 antibody
  • Llglh antibody
  • Mgl1 antibody
  • Rgl1 antibody

Protein level used designations for LLGL1

disks large homolog 4 , lethal(2) giant larvae protein homolog 1 , human homolog to the D-lgl gene protein , LLGL , mgl-1 , mlgl , rgl-1

GENE ID SPECIES
714273 Macaca mulatta
3996 Homo sapiens
489538 Canis lupus familiaris
781865 Bos taurus
16897 Mus musculus
54265 Rattus norvegicus
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