You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) LRP5 antibody for Immunoprecipitation

Recommended LRP5 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
  • bmnd1
  • BMND1
  • evr1
  • EVR1
  • EVR4
  • evr4
  • HBM
  • hbm
  • lr3
  • LR3
  • LRP5
  • lrp5-A
  • LRP6
  • LRP7
  • lrp7
  • mKIAA4142
  • OPPG
  • oppg
  • OPS
  • ops
  • OPTA1
  • opta1
  • VBCH2
  • vbch2
  • Xlrp5
Reactivity
Mouse (Murine), Human
98
59
40
1
1
1
1
1
Host
Rabbit
91
15
12
2
Clonality
Polyclonal
Conjugate
This LRP5 antibody is un-conjugated
8
8
7
5
5
5
3
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
75
59
31
23
14
6
4
2
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN3020645
$ 302.50
Plus shipping costs $45.00

Similar anti-LRP5 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 17 Antibodies 46 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 4 Antibodies
Immunofluorescence (IF) 1 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies
Immunohistochemistry (IHC) 8 Antibodies 32 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies 14 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 33 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
Reactivity Mouse (Murine), Human
(98), (59), (40), (1), (1), (1), (1), (1)
Host Rabbit
(91), (15), (12), (2)
Clonality
Polyclonal
Conjugate This LRP5 antibody is un-conjugated
(8), (8), (7), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(75), (59), (31), (23), (14), (6), (4), (2), (2), (2), (1)
Supplier Log in to see

Product Details anti-LRP5 Antibody

Target Details LRP5 Application Details Handling Images
Purification Affinity purification
Immunogen A synthetic peptide of human LRP5   
Isotype IgG

Target Details LRP5

Product Details anti-LRP5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name LRP5 (LRP5 Antibody Abstract)
Background LRP5 and LRP6 are single-pass transmembrane proteins belonging to the low-density lipoprotein receptor (LDLR)-related protein family. Unlike other members of the LDLR family, LRP5 and LRP6 have four EGF and three LDLR repeats in the extracellular domain, and proline-rich motifs in the cytoplasmic domain. They function as co-receptors for Wnt and are required for the canonical Wnt/beta-catenin signaling pathway. LRP5 and LRP6 are highly homologous and have redundant roles during development. The activity of LRP5 and LRP6 can be inhibited by the binding of some members of the Dickkopf (DKK) family of proteins. Upon stimulation with Wnt, LRP6 is phosphorylated at multiple sites including Thr1479, Ser1490, and Thr1493 by kinases such as GSK-3 and CK1. Phosphorylated LRP6 recruits axin to the membrane and presumably activates beta-catenin signaling. LRP5 is involved in the regulation of bone homeostasis. Mutations and polymorphisms in LPR5 are associated with bone diseases like osteoporosis-pseudoglioma syndrome and high-bone-mass disorders. In addition, mutations in LRP5 are found in patients with hyperparathyroid tumor and breast cancer.
Synonyms: LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
Gene ID 4041
UniProt O75197
Research Area Stem Cells, Wnt, Extracellular Matrix
Pathways WNT Signaling

Application Details

Product Details anti-LRP5 Antibody Target Details LRP5 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:200-1:500, IHC: 1:50-1:100, IF: 1:20-1:50, IP: 1:20-1:50
Restrictions For Research Use only

Handling

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-LRP5 antibody (Low Density Lipoprotein Receptor-Related Protein 5) (ABIN3020645) Western blot analysis of extracts of various tissues, using LRP5 antibody.