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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|Immunofluorescence (fixed cells) (IF/ICC)||1 Antibodies|
|Western Blotting (WB)||46 Antibodies||16 Antibodies|
|Immunoprecipitation (IP)||2 Antibodies||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||11 Antibodies||8 Antibodies|
|Immunohistochemistry (IHC)||13 Antibodies||6 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||29 Antibodies||29 Antibodies|
|Immunofluorescence (IF)||2 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies||1 Antibodies|
|Antigen||Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies|
|Epitope||AA 1201-1215, C-Term Alternatives|
|Reactivity||Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This LRP5 antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-LRP5 AntibodyTarget Details LRP5 Application Details Handling Images
Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for Low-density lipoprotein receptor-related protein 5(LRP5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: low density lipoprotein receptor-related protein 5
Protein Name: Low-density lipoprotein receptor-related protein 5
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human LRP5(1201-1215aa IHAVEEVSLEEFSAH), identical to the related mouse and rat sequences.|
Target Details LRP5Product Details anti-LRP5 Antibody Application Details Handling Images back to top
|Alternative Name||LRP5 (LRP5 Antibody Abstract)|
|Background||Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. It is mapped to 11q13.2. LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with diabetes mellitus type 1 in humans. This protein plays a key role in skeletal homeostasis. In addition to that, the binding of axin to LRP5 is an important part of the Wnt signal transduction pathway, and it also acts as a target for the inhibitory effects of Dickkopf, another developmental protein, on Wnt signaling.|
|Research Area||Stem Cells, Wnt, Extracellular Matrix, Wnt Signaling|
|Pathways||WNT Signaling, Stem Cell Maintenance|
Application DetailsProduct Details anti-LRP5 Antibody Target Details LRP5 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LRP5 Antibody Target Details LRP5 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Thimerosal (Merthiolate),Sodium azide a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
ImagesProduct Details anti-LRP5 Antibody Target Details LRP5 Application Details Handling back to top