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Browse our anti-LRP6 (LRP6) Antibodies

Full name:
anti-Low Density Lipoprotein Receptor-Related Protein 6 Antibodies (LRP6)
On www.antibodies-online.com are 71 Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Antibodies from 17 different suppliers available. Additionally we are shipping LRP6 Kits (28) and LRP6 Proteins (8) and many more products for this protein. A total of 111 LRP6 products are currently listed.
Synonyms:
ADCAD2, C030016K15Rik, Cd, Gw, LRP6, lrp6-A, Xlrp6
list all antibodies Gene Name GeneID UniProt
LRP6 4040 O75581
LRP6 16974 O88572
LRP6 312781  

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anti-Human LRP6 Antibodies:

anti-Mouse (Murine) LRP6 Antibodies:

anti-Rat (Rattus) LRP6 Antibodies:

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Top referenced anti-LRP6 Antibodies

  1. Human Polyclonal LRP6 Primary Antibody for IHC (p), WB - ABIN390100 : Brown, Twells, Hey, Cox, Levy, Soderman, Metzker, Caskey, Todd, Hess: Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. in Biochemical and biophysical research communications 1998 (PubMed)
    Show all 4 references for ABIN390100

  2. Human Polyclonal LRP6 Primary Antibody for EIA, IHC (p) - ABIN358636 : Liu, Bafico, Harris, Aaronson: A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for ABIN358636

  3. Human Polyclonal LRP6 Primary Antibody for IHC, ELISA - ABIN185307 : Tamai, Semenov, Kato, Spokony, Liu, Katsuyama, Hess, Saint-Jeannet, He: LDL-receptor-related proteins in Wnt signal transduction. in Nature 2000 (PubMed)
    Show all 2 references for ABIN185307

  4. Human Polyclonal LRP6 Primary Antibody for IF (cc), IF (p) - ABIN743558 : Chen, Xu, Ye, Li, Gong, Zhang, Wu, Jia, Liu, Chen, Yang, Tang, Zhu, Ge, Zou: Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling. in Journal of cellular and molecular medicine 2014 (PubMed)

More Antibodies against LRP6 Interaction Partners

Xenopus laevis Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) interaction partners

  1. Lrp6 asymmetry is controlled by Wnt (show WNT2 Antibodies)/PCP (show PRCP Antibodies) signaling, indicating that this pathway regulates not only planar- but also apicobasal cell polarity.

  2. PTK7 (show PTK7 Antibodies) and LRP6 proteins physically interact, suggesting that PTK7 (show PTK7 Antibodies) stabilization of LRP6 protein reciprocally regulates both canonical and noncanonical Wnt (show WNT2 Antibodies) activities in the embryo.

  3. Results suggest that Rap2 (show RAP2A Antibodies) acts via TNIK (show TNIK Antibodies) to regulate the stability of LRP6 receptor for Wnt (show WNT2 Antibodies) signaling.

  4. The extracellular domains of Lrp5 (show LRP5 Antibodies)/6 behave as physiologically relevant inhibitors of noncanonical Wnt (show WNT2 Antibodies) signaling during Xenopus and mouse development in vivo.

  5. Lrp6 plays a critical role in the switch from Wnt (show WNT2 Antibodies)/PCP (show PRCP Antibodies) to Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  6. Kremen2 (show KREMEN2 Antibodies) knockdown specifically reduces LRP6 protein levels in neural crest explants.

Zebrafish Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) interaction partners

  1. Waif1a binds to the Wnt (show WNT2 Antibodies) coreceptor LRP6 (show LRP5 Antibodies) and inhibits Wnt (show WNT2 Antibodies)-induced LRP6 (show LRP5 Antibodies) internalization into endocytic vesicles, a process that is required for pathway activation.

  2. Results identify GRK5 (show GRK5 Antibodies)/6 as novel kinases for the single transmembrane receptor LRP6 (show LRP5 Antibodies) during Wnt (show WNT2 Antibodies) signaling.

Human Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) interaction partners

  1. Accordingly, we propose that the anti-fibrotic activity of adiponectin (show ADIPOQ Antibodies) may be mediated through AdipoR1 (show ADIPOR1 Antibodies)/R2 receptors

  2. findings suggest that rescuing LRP5 (show LRP5 Antibodies)/6-mediated Wnt (show WNT2 Antibodies) signaling improves neuronal cell survival and reduces tau phosphorylation, which support the hypothesis that Wnt (show WNT2 Antibodies) signaling might be an attractive therapeutic strategy for managing AD

  3. Results suggest that miR (show MLXIP Antibodies)-126 functions as a tumor-suppressive miRNA by targeting LRP6 regulating Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway in papillary thyroid carcinoma.

  4. miR513c functions as a tumor suppressor miRNA, mediated predominantly through the direct suppression of the expression of LRP6.

  5. The interaction between Wnt (show WNT2 Antibodies) isoforms and their LRP6 cognate receptor depends on the jutting loop present in Wnt3a (show WNT3A Antibodies) but absent in Wnt5b (show WNT5B Antibodies).

  6. LRP6 and VEGF levels in the vitreous body from patients with proliferative diabetic retinopathy were increased and correlated mutually.

  7. Lrp6 (show LRP5 Antibodies) binds to Frizzled, preventing Frz-regulated non-canonical Wnt (show WNT2 Antibodies) pathway activation and further non-canonical pathway-mediated tumour metastasis.

  8. No mutations in LRP5 (show LRP5 Antibodies) and LRP6 could be identified

  9. LRP6 variants may be associated with risk of ischaemic stroke.

  10. Particularly for TNBC associated with Skp2/LRP6 overexpression.

Mouse (Murine) Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) interaction partners

  1. These results revealed a new role of the canonical Lrp5 (show LRP5 Antibodies)/6-beta-catenin (show CTNNB1 Antibodies) pathway in regulating the morphogenesis of the cerebellum during postnatal development.

  2. Data (including data from studies in knockout/transgenic mice) suggest Lrp6 is required for suppression of Sost (sclerostin (show SOST Antibodies)) expression by parathyroid hormone (show PTH Antibodies) (here, human PTH (show PTH Antibodies) peptide 1-34); LRP6 regulates osteocytes expression of histone deacetylases.

  3. Lrp5 (show LRP5 Antibodies) binds to Frizzled, preventing Frz-regulated non-canonical Wnt (show WNT2 Antibodies) pathway activation and further non-canonical pathway-mediated tumour metastasis.

  4. Wt1 (show WT1 Antibodies) expression levels in podocytes regulate Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling through modulating the endocytic fate of LRP6, and this indicates a potential target for the therapy of CKD.

  5. N-cadherin (show CDH2 Antibodies) modulates Lrp6/PTHR1 (show PTH1R Antibodies) interaction, restraining the intensity of parathyroid hormone (show PTH Antibodies)-induced beta-catenin (show CTNNB1 Antibodies) signaling

  6. LRP6 restrains vascular smooth muscle lineage noncanonical signals that promote osteochondrogenic differentiation, mediated in part via USF1 (show USF1 Antibodies)- and arginine methylation-dependent relays.

  7. Urotensin II (show UTS2 Antibodies) inhibited the proliferation of cardiac side population cells by JNK (show MAPK8 Antibodies)/LRP6 signalling during pressure overload.

  8. Hgf (show HGF Antibodies) as an important transactivator of canonical Wnt (show WNT2 Antibodies) signaling that is mediated by Met-stimulated, Gsk3 (show GSK3b Antibodies)-dependent Lrp5 (show LRP5 Antibodies)/6 phosphorylation

  9. miR (show MLXIP Antibodies)-183, though negatively regulated by Gata3 (show GATA3 Antibodies), enhances 3T3-L1 preadipocyte differentiation and adipogenesis by targeting LRP6.

  10. Phosphorylation of LRP6 was increased after tissue plasminogen activator (tPA (show PLAT Antibodies)) treatment and decreased by tPA (show PLAT Antibodies) siRNA transfection.

LRP6 Antigen Profile

Antigen Summary

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Alternative names and synonyms associated with LRP6

  • low density lipoprotein receptor-related protein 6 (LRP6) antibody
  • low density lipoprotein receptor-related protein 6 (lrp6-A) antibody
  • low density lipoprotein receptor-related protein 6 (lrp6-b) antibody
  • low-density lipoprotein receptor-related protein 6 (lrp6) antibody
  • low density lipoprotein receptor-related protein 6 (lrp6) antibody
  • low density lipoprotein receptor-related protein 6 (Lrp6) antibody
  • ADCAD2 antibody
  • C030016K15Rik antibody
  • Cd antibody
  • Gw antibody
  • LRP6 antibody
  • lrp6-A antibody
  • Xlrp6 antibody

Protein level used designations for LRP6

low density lipoprotein receptor-related protein 6 , lipoprotein receptor-related protein 6 , low-density lipoprotein receptor-related protein 6 , low-density lipoprotein receptor-related protein 6-like , LRP-6 , crooked , low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6 , low density lipoprotein-related protein 6

GENE ID SPECIES
100063409 Equus caballus
373826 Xenopus laevis
378494 Xenopus laevis
465295 Pan troglodytes
100003877 Danio rerio
100389922 Callithrix jacchus
100477840 Ailuropoda melanoleuca
100489328 Xenopus (Silurana) tropicalis
4040 Homo sapiens
477692 Canis lupus familiaris
16974 Mus musculus
312781 Rattus norvegicus
100352000 Oryctolagus cuniculus
100735282 Cavia porcellus
100515777 Sus scrofa
536328 Bos taurus
419097 Gallus gallus
590395 Strongylocentrotus purpuratus
101112971 Ovis aries
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