anti-Human LRP6 antibody for Immunofluorescence (Cultured Cells)

Recommended LRP6 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Antibodies
  • lrp6-A
  • Xlrp6
  • adcad2
  • lrp6
  • LRP6
  • ADCAD2
  • C030016K15Rik
  • Cd
  • Gw
  • low density lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6
  • LRP6
  • lrp6-A
  • lrp6-b
  • lrp6
  • Lrp6
Epitope
AA 1470-1520, pSer1490
14
14
12
12
8
8
6
5
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
91
21
5
3
1
1
1
1
1
1
Host
Rabbit
58
18
15
1
Clonality
Polyclonal
Conjugate
This LRP6 antibody is un-conjugated
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
35
33
33
20
19
13
12
3
2
2
1
1
Options
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Catalog No. ABIN743558
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2808136 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN743564 IF (cc) IF (p) Cy7 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN874342 IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN874346 IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN874343 IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN874344 IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN743561 IF (cc) IF (p) Cy3 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN743562 IF (cc) IF (p) Cy5 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN743563 IF (cc) IF (p) Cy5.5 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN743565 IF (cc) IF (p) FITC Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN5006311 IF (cc) IF (p) Alexa Fluor 680 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal
1 ABIN5006312 IF (cc) IF (p) Alexa Fluor 750 Rabbit IgG AA 1470-1520, pSer1490 Log in to see Polyclonal

Top referenced anti-LRP6 antibody for Immunofluorescence (Cultured Cells)

Similar anti-LRP6 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 2 Antibodies 33 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies 13 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 4 Antibodies 32 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 5 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 19 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies

General

Antigen Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Antibodies
Epitope AA 1470-1520, pSer1490
(14), (14), (12), (12), (8), (8), (6), (5), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(91), (21), (5), (3), (1), (1), (1), (1), (1), (1)
Host Rabbit
(58), (18), (15), (1)
Clonality
Polyclonal
Conjugate This LRP6 antibody is un-conjugated
(3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(35), (33), (33), (20), (19), (13), (12), (3), (2), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-LRP6 Antibody

Target Details LRP6 Application Details Handling ProductDetails: References for anti-LRP6 antibody (ABIN743558) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Ser1490
Isotype IgG

Target Details LRP6

Product Details anti-LRP6 Antibody Application Details Handling ProductDetails: References for anti-LRP6 antibody (ABIN743558) Images back to top
Antigen
Alternative Name Lrp6 (LRP6 Antibody Abstract)
Background

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).

Subcellular location: Cytoplasm


Synonyms: ADCAD2, Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6
Gene ID 4040
UniProt O75581
Research Area Stem Cells, Wnt
Pathways WNT Signaling, Tube Formation

Application Details

Product Details anti-LRP6 Antibody Target Details LRP6 Handling ProductDetails: References for anti-LRP6 antibody (ABIN743558) Images back to top
Application Notes IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details ProductDetails: References for anti-LRP6 antibody (ABIN743558) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-LRP6 antibody (ABIN743558)

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details Handling Images back to top
Product cited in:

Boone, Arend, Johnston, Cooper, Gilchrist, Oelschlager, Grizzle, McGwin, Gangrade, Straughn, Buchsbaum: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, 2016

Chen, Xu, Ye, Li, Gong, Zhang, Wu, Jia, Liu, Chen, Yang, Tang, Zhu, Ge, Zou: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, 2014

Images

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details Handling ProductDetails: References for anti-LRP6 antibody (ABIN743558) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-LRP6 antibody (Low Density Lipoprotein Receptor-Related Protein 6) (AA 1470-1520) (ABIN743558) Paraformaldehyde-fixed, paraffin embedded rat stomach; Antigen retrieval by boiling i...