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anti-Human LRP6 antibody for Western Blotting

Recommended LRP6 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Antibodies
  • ADCAD2
  • adcad2
  • C030016K15Rik
  • Cd
  • Gw
  • LRP6
  • lrp6
  • lrp6-A
  • Xlrp6
Epitope
AA 1531-1560, C-Term
13
13
13
10
8
7
5
2
1
1
1
1
Reactivity
Human
78
19
5
3
1
1
1
1
1
Host
Rabbit
57
14
7
1
Clonality
Polyclonal
Conjugate
This LRP6 antibody is un-conjugated
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
33
31
30
19
12
11
8
3
2
1
1
1
Supplier
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Catalog No. ABIN390100
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13476625 ABIN1873565 IHC WB Rabbit IgG Log in to see Polyclonal
0.13476625 ABIN1859708 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 981-1213 Log in to see Polyclonal
0.13476625 ABIN2444998 IHC WB Rabbit Ig Fraction C-Term Log in to see Polyclonal
0.13476625 ABIN3015245 IHC WB Rabbit Log in to see Polyclonal
0.0011760078 ABIN358636 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 3
0.0011760078 ABIN185307 IHC ELISA WB Goat Internal Region Log in to see Polyclonal 2
0.0011760078 ABIN303214 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal
0.0011760078 ABIN2465909 IHC ELISA WB Goat Internal Region Log in to see Polyclonal
0.0011760078 ABIN467536 WB Rabbit Log in to see Polyclonal
0.0011760078 ABIN1910472 IHC ELISA WB Biotin Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN1910473 IHC ELISA WB FITC Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN1910474 IHC ELISA WB PE Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN1910470 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN1910471 IHC ELISA WB APC Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN1823105 WB Rabbit IgG Log in to see Polyclonal
0.0011760078 ABIN596312 IP WB Rabbit IgG Log in to see
0.0011760078 ABIN2624977 WB Rabbit IgG AA 1171-1469 Log in to see Polyclonal
0.0011760078 ABIN1910475 IHC ELISA WB HRP Rabbit IgG C-Term Log in to see Polyclonal
0.0011760078 ABIN2737121 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011760078 ABIN2613299 WB FITC Rabbit IgG AA 981-1213 Log in to see Polyclonal

Top referenced anti-LRP6 antibody for Western Blotting

Similar anti-LRP6 Antibodies

Application / Reactivity Human
ELISA 34 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 8 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 30 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 33 Antibodies

General

Antigen Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Antibodies
Epitope AA 1531-1560, C-Term
(13), (13), (13), (10), (8), (7), (5), (2), (1), (1), (1), (1)
Reactivity Human
(78), (19), (5), (3), (1), (1), (1), (1), (1)
Host Rabbit
(57), (14), (7), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This LRP6 antibody is un-conjugated
(3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(33), (31), (30), (19), (12), (11), (8), (3), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-LRP6 Antibody

Target Details LRP6 Application Details Handling References for anti-LRP6 Antibody (ABIN390100) Images
Specificity This LRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1538~1568 amino acids from the C-terminal region of human LRP6.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This LRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1531-1560 AA from the C-terminal region of human LRP6.
Clone RB01837
Isotype Ig

Target Details LRP6

Product Details anti-LRP6 Antibody Application Details Handling References for anti-LRP6 Antibody (ABIN390100) Images back to top
Antigen
Alternative Name LRP6 (LRP6 Antibody Abstract)
Background LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
Synonyms: LDL receptor-related protein 6
Molecular Weight 180442 DA
Gene ID 4040
UniProt O75581
Research Area Stem Cells, Cell Structure
Pathways WNT Signaling

Application Details

Product Details anti-LRP6 Antibody Target Details LRP6 Handling References for anti-LRP6 Antibody (ABIN390100) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details References for anti-LRP6 Antibody (ABIN390100) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-LRP6 Antibody (ABIN390100)

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details Handling Images back to top
Product cited in:

Ye, Go, Singh, Liu, Keramati, Mani: "LRP6 protein regulates low density lipoprotein (LDL) receptor-mediated LDL uptake." in: The Journal of biological chemistry, Vol. 287, Issue 2, pp. 1335-44, 2012

Keramati, Singh, Lin, Faramarzi, Ye, Mane, Tellides, Lifton, Mani: "Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 5, pp. 1914-8, 2011

Liu, Prior, Piwnica-Worms, Bu: "LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 11, pp. 5136-41, 2010

Background publications

Brown, Twells, Hey, Cox, Levy, Soderman, Metzker, Caskey, Todd, Hess: "Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family." in: Biochemical and biophysical research communications, Vol. 248, Issue 3, pp. 879-88, 1998

Images

Product Details anti-LRP6 Antibody Target Details LRP6 Application Details Handling References for anti-LRP6 Antibody (ABIN390100) back to top
Supplier Images
Western Blotting (WB) image for anti-LRP6 antibody (Low Density Lipoprotein Receptor-Related Protein 6) (AA 1531-1560) (ABIN390100) Western blot analysis of LRP6 (arrow) using rabbit polyclonal LRP6 Antibody (C-term T...
Immunohistochemistry (IHC) image for anti-LRP6 antibody (Low Density Lipoprotein Receptor-Related Protein 6) (AA 1531-1560) (ABIN390100) Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with LRP6 ...