Browse our anti-PKC beta (PRKCB) Antibodies

On www.antibodies-online.com are 192 Protein Kinase C, beta (PRKCB) Antibodies from 27 different suppliers available. Additionally we are shipping PKC beta Kits (33) and PKC beta Proteins (22) and many more products for this protein. A total of 261 PKC beta products are currently listed.
Synonyms:
A130082F03Rik, PKC, PKC-B, PKC-Beta, Pkcb, Prkcb, Prkcb1, Prkcb2, zgc:63591
list all antibodies Gene Name GeneID UniProt
PRKCB 5579 P05771
PRKCB 18751 P68404
PRKCB 25023 P68403

Most Popular Reactivities for anti-PKC beta (PRKCB) Antibodies

anti-Human PKC beta Antibodies:

anti-Mouse (Murine) PKC beta Antibodies:

anti-Rat (Rattus) PKC beta Antibodies:

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More Antibodies against PKC beta Interaction Partners

Human Protein Kinase C, beta (PRKCB) interaction partners

  1. a primary functional variant of PRKCB (rs35015313) was identified by genotype imputation using a phased panel of 1,070 Japanese individuals from a prospective, general population cohort study and subsequent in vitro functional analyses. These results may lead to improved understanding of the disease pathways involved in primary biliary cholangitis.

  2. our findings identify PRKCB gene as a novel candidate gene for familial Meniere's Disease (MD )and its expression gradient in supporting cells of the organ of Corti deserves attention, given the role of supporting cells in K(+ )recycling within the endolymph, and its apical turn location may explain the onset of hearing loss at low frequencies in MD

  3. Activation of the Pro-Oxidant PKCbetaII-p66Shc (show SHC1 Antibodies) Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Patients With Diabetes With Critical Limb Ischemia

  4. Taken together, these data argue for a complex mechanism of PKC-beta-dependent regulation of SH (show POLD3 Antibodies)CA (p66) activation invol (show SIGLEC1 Antibodies)ving Ser(139) and a motif surroun (show SIGLEC1 Antibodies)ding Ser(213).

  5. The study aimed to identify a small set of genetic signatures that may reliably predict the individuals with a high genetic propensity to heroin addiction. A set of 4 genes (JUN (show JUN Antibodies), CEBPB (show CEBPB Antibodies), PRKCB, ENO2 (show ENO2 Antibodies), or CEBPG (show CEBPG Antibodies)) could predict the diagnosis of heroin addiction with the accuracy rate around 85% in our dataset.

  6. Our results provide compelling evidence that glucose-induced PKCalpha (show PKCa Antibodies)/PKCbeta-mediated inhibition of Kv current in vascular smooth muscle causes an enhanced constrictor response. Inhibition of Kv current causes a significant depolarization of vascular myocytes leading to marked vasoconstriction

  7. Data suggest that targeted manipulation of protein kinase C (show PKC Antibodies) isoforms PKCalpha (show PKCa Antibodies), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 (show TRPC6 Antibodies) protein (TRPC6 (show TRPC6 Antibodies)) functions.

  8. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kdelta or PKCbeta signaling pathways.

  9. PPAR-delta (show PPARD Antibodies) and NKIRAS1 (show NKIRAS1 Antibodies) are downstream mediators in the PRKCB pathway in human umbilical vein endothelial cells.

  10. Lower hydrogen sulfide (show SQRDL Antibodies) is associated with cardiovascular mortality, which involves PKCBII/Akt (show AKT1 Antibodies) pathway in chronic hemodialysis patients.

Cow (Bovine) Protein Kinase C, beta (PRKCB) interaction partners

  1. The study identified the serine phosphorylation (p-Ser) sites induced by (show IRS2 Antibodies)PKC-Beta activation or AGT, which inhibits insulin-induced p-Tyr sites on IRS2 and its signals in endothelial cells.

Mouse (Murine) Protein Kinase C, beta (PRKCB) interaction partners

  1. Cytosolic NELL2 specifically interacts with PKC beta isotypes and inhibits PKC beta1 through direct binding to the N-terminal pseudosubstrate domain of PKC beta1.

  2. Taken together, these data argue for a complex mechanism of PKCbeta-dependent regulation of p66 (show POLD3 Antibodies) activation involving Ser (show SIGLEC1 Antibodies)(139) and a motif surrounding Ser (show SIGLEC1 Antibodies)(213).

  3. Translocation of PKC-betaII from the cytoplasm to membranes is required for phagocytosis of apoptotic cells and is inhibited by soluble beta-glucan

  4. repressor of myogenesis; opposes calcineurin (show PPP3CA Antibodies) function

  5. at the functionally mature calyx of Held synapse the Ca(2 (show CA2 Antibodies)+)-dependent protein kinase C (show PKC Antibodies) isoforms alpha and beta are necessary for post-tetanic potentiation, a form of plasticity thought to underlie short-term memory

  6. a new mechanism by which PKC-beta activation promotes EC dysfunction caused by the de-regulation of the IL-18 (show IL18 Antibodies)/IL-18BP (show IL18BP Antibodies) pathway, leading to increased VCAM-1 (show VCAM1 Antibodies) expression, monocyte/macrophage adhesion, and accelerated atherosclerotic plaque formation in diabetes

  7. These results demonstrate the importance of PKCbetaII in chronic lymphocytic leukemia-like disease progression and suggest a role for PKCalpha (show PKCa Antibodies) subversion in creating permissive conditions for leukemogenesis.

  8. PKCbeta2 inhibition protects mice from gut (show GUSB Antibodies) ischemia-reperfusion injury by suppressing the adaptor p66(Shc)-mediated oxidative stress and subsequent apoptosis.

  9. PKC-alpha (show PKCa Antibodies) and -betaIotaIota are the predominant isoforms in the developing optic pathway, whereas PKC-epsilon (show PRKCE Antibodies) is the major form in the chiasmatic neurons.

  10. STAT3 (show STAT3 Antibodies) bound to previously undescribed negative regulatory elements within the promoter of PRKCB, which encodes PKCbetaII.

PKC beta (PRKCB) Antigen Profile

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with PKC beta (PRKCB)

  • protein kinase C, beta b (prkcbb) antibody
  • protein kinase C, beta (PRKCB) antibody
  • protein kinase C, beta (Prkcb) antibody
  • A130082F03Rik antibody
  • PKC antibody
  • PKC-B antibody
  • PKC-Beta antibody
  • Pkcb antibody
  • Prkcb antibody
  • Prkcb1 antibody
  • Prkcb2 antibody
  • zgc:63591 antibody

Protein level used designations for PRKCB

PKC-beta , protein kinase C beta type , protein kinase C, beta 1 , protein kinase C, beta , PKC-B , protein kinase C, beta 1 polypeptide , protein kinase C beta 2 , protein kinase C beta-II , protein kinase C beta I , protein kinase C beta II , protein kinase C beta 1

GENE ID SPECIES
393953 Danio rerio
100590939 Nomascus leucogenys
5579 Homo sapiens
397183 Sus scrofa
282325 Bos taurus
18751 Mus musculus
25023 Rattus norvegicus
100037719 Oryctolagus cuniculus
489968 Canis lupus familiaris
416567 Gallus gallus
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