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anti-Rabbit PKC beta antibody for Enzyme Immunoassay

Recommended PKC beta Antibody (supplied by: Log in to see )

Antigen
Protein Kinase C, beta (PRKCB) Antibodies
  • A130082F03Rik
  • PKC
  • PKC-B
  • PKC-Beta
  • PKC-beta
  • PKCB
  • Pkcb
  • Prkcb
  • Prkcb1
  • PRKCB1
  • prkcb1
  • PRKCB2
  • Prkcb2
  • zgc:63591
Epitope
Internal Region
44
22
17
12
11
10
7
7
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Monkey, Mouse (Murine), Rabbit, Rat (Rattus)
130
76
71
11
7
5
5
2
1
1
Host
Rabbit
147
13
7
7
Clonality
Polyclonal
Conjugate
This PKC beta antibody is un-conjugated
10
9
5
5
5
5
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
150
95
61
22
15
8
6
5
3
3
2
2
1
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Catalog No. ABIN401431
$ 500.50
Plus shipping costs $45.00

Top referenced anti-PKC beta antibody for Enzyme Immunoassay

Similar anti-PKC beta Antibodies

Application / Reactivity Human Cow (Bovine) Mouse (Murine) Rat (Rattus) Monkey Rabbit
Western Blotting (WB) 117 Antibodies 7 Antibodies 68 Antibodies 61 Antibodies 8 Antibodies 9 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 3 Antibodies 4 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 9 Antibodies 5 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 41 Antibodies 35 Antibodies 24 Antibodies 4 Antibodies 2 Antibodies 2 Antibodies

General

Antigen Protein Kinase C, beta (PRKCB) Antibodies
Epitope Internal Region
(44), (22), (17), (12), (11), (10), (7), (7), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Monkey, Mouse (Murine), Rabbit, Rat (Rattus)
(130), (76), (71), (11), (7), (5), (5), (2), (1), (1)
Host Rabbit
(147), (13), (7), (7)
Clonality
Polyclonal
Conjugate This PKC beta antibody is un-conjugated
(10), (9), (5), (5), (5), (5), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(150), (95), (61), (22), (15), (8), (6), (5), (3), (3), (2), (2), (1)
Pubmed 4 references available
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Product Details anti-PKC beta Antibody

Target Details PKC beta Application Details Handling References for anti-PKC beta Antibody (ABIN401431) Images
Specificity This antibody is specific for PKC beta protein.
Cross-Reactivity (Details) Species reactivity (expected):Rabbit, Bovine, Rat, Mouse.
Species reactivity (tested):Human, Monkey.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to an internal region of human Protein kinase C beta
Isotype IgG

Target Details PKC beta

Product Details anti-PKC beta Antibody Application Details Handling References for anti-PKC beta Antibody (ABIN401431) Images back to top
Antigen
Alternative Name PRKCB (PRKCB Antibody Abstract)
Background Protein kinase C (PKC) beta is implicated as a potential important factor in cancer cell proliferation and angiogenesis. PKC is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: PKC beta, PKC-B, PKC-beta, PKCB, PRKCB1, Protein kinase C beta type
Gene ID 5579
NCBI Accession NP_002729
UniProt P05771
Pathways WNT Signaling

Application Details

Product Details anti-PKC beta Antibody Target Details PKC beta Handling References for anti-PKC beta Antibody (ABIN401431) Images back to top
Application Notes ELISA: 1/75,000 - 1/80,000. Western Blot: 1/1,000 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PKC beta Antibody Target Details PKC beta Application Details References for anti-PKC beta Antibody (ABIN401431) Images back to top
Format Liquid
Concentration 1.0 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Az
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

References for anti-PKC beta Antibody (ABIN401431)

Product Details anti-PKC beta Antibody Target Details PKC beta Application Details Handling Images back to top
Background publications

Chen, Petrelli, Olesiak, Wilson, Labello, Pankiewicz: "Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase." in: Bioorganic & medicinal chemistry, Vol. 16, Issue 15, pp. 7462-9, 2008

Koivunen, Aaltonen, Koskela, Lehenkari, Laato, Peltonen: "Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells." in: Cancer research, Vol. 64, Issue 16, pp. 5693-701, 2004

Zhang, Wang, Petrin, Bishop, Bond: "Characterization of site-specific mutants altered at protein kinase C beta 1 isozyme autophosphorylation sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 13, pp. 6130-4, 1993

Flint, Paladini, Koshland: "Autophosphorylation of protein kinase C at three separated regions of its primary sequence." in: Science (New York, N.Y.), Vol. 249, Issue 4967, pp. 408-11, 1990

Images

Product Details anti-PKC beta Antibody Target Details PKC beta Application Details Handling References for anti-PKC beta Antibody (ABIN401431) back to top
Supplier Images
 image for anti-PKC beta antibody (Protein Kinase C, beta) (Internal Region) (ABIN401431) anti-Protein Kinase C, beta (PRKCB) (Internal Region) antibody