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Browse our PKC beta Proteins (PRKCB)

Full name:
Protein Kinase C, beta Proteins (PRKCB)
On are 19 Protein Kinase C, beta (PRKCB) Proteins from 8 different suppliers available. Additionally we are shipping PKC beta Antibodies (176) and PKC beta Kits (33) and many more products for this protein. A total of 242 PKC beta products are currently listed.
A130082F03Rik, PKC, PKC-B, PKC-Beta, Pkcb, Prkcb, Prkcb1, Prkcb2, zgc:63591
list all proteins Gene Name GeneID UniProt
PRKCB 5579 P05771
PRKCB 18751 P68404
PRKCB 25023 P68403

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PKC beta Proteins (PRKCB) by Origin

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More Proteins for PKC beta Interaction Partners

Human Protein Kinase C, beta (PRKCB) interaction partners

  1. PPAR-delta (show PPARD Proteins) and NKIRAS1 (show NKIRAS1 Proteins) are downstream mediators in the PRKCB pathway in human umbilical vein endothelial cells.

  2. Lower hydrogen sulfide (show SQRDL Proteins) is associated with cardiovascular mortality, which involves PKCBII/Akt (show AKT1 Proteins) pathway in chronic hemodialysis patients.

  3. Study found a significant decrease of PRCKB1 mRNA expression in subsyndromal symptomatic depression, suggesting PRKCB1 might be a candidate gene and biomarker

  4. PKCbetaII inhibits the ubiquitination of beta-arrestin2 (show ARRB2 Proteins) in an autophosphorylation-dependent manner

  5. Ionizing radiation-induced eNOS (show NOS3 Proteins) activation in human vascular endothelial cells is attributed to both the up-regulation of PKC (show PRRT2 Proteins)-betaII and the increase in ROS (show ROS1 Proteins) generation which were independent of each other.

  6. Effect of PKC-beta Signaling Pathway on Expression of MCP-1 (show CCL2 Proteins) and VCAM-1 (show VCAM1 Proteins) in Different Cell Models in Response to Advanced Glycation End Products

  7. Data show that in K562 cells, the protein kinase C alpha (PKCalpha (show PKCa Proteins)) and protein kinase C beta II (PKCbetaII) expressions enhanced in the presence of the drug when the growth was inhibited.

  8. Direct interaction between the two proteins leads to Apoptin-induced activation of PKC and consequently activated PKCbetaI mediates phosphorylation of Apoptin to promote its tumour-specific nuclear translocation and cytotoxic function.

  9. Gene fusions involving PRKC genes occur in several morphological and clinical subsets of benign fibrous histiocytoma, but they seem to account for only a minority of the cases.

  10. PMA primed PBTLs for polarization under flow, with protein kinase C (PKC)-delta enriched in the leading edge, PKC-betaI in the microtubule organizing center, and PKC-betaII in the uropod and peripheral region.

Pig (Porcine) Protein Kinase C, beta (PRKCB) interaction partners

  1. first study to show the expression and cellular localization of PKC beta I in the retina of pigs with development, and these results suggest that PKC beta I, in accordance with PKC alpha (show PKCa Proteins), plays important roles in signal transduction pathways in the pig retina with development

  2. Increases in epicardial perivascular adipose tissue leptin (show LEP Proteins) exacerbate coronary endothelial dysfunction in MetS via a PKC-beta-dependent pathway.

  3. ET-1 (show EDN1 Proteins)-mediated myocardial contractile dysfunction during cardioplegia involves activation of protein kinase C beta II.

  4. The PKCalpha (show PKCa Proteins), PKCbeta1, and PKCbeta2 mRNA levels tended to be lower in ischemia-reperfused than in sham-operated eyes in both the retinal arteries and the neuroretina.

Cow (Bovine) Protein Kinase C, beta (PRKCB) interaction partners

  1. The study identified the serine phosphorylation (p-Ser) sites induced by (show IRS2 Proteins)PKC-Beta activation or AGT, which inhibits insulin-induced p-Tyr sites on IRS2 and its signals in endothelial cells.

Mouse (Murine) Protein Kinase C, beta (PRKCB) interaction partners

  1. repressor of myogenesis; opposes calcineurin (show PPP3CA Proteins) function

  2. at the functionally mature calyx of Held synapse the Ca(2+)-dependent protein kinase C isoforms alpha and beta are necessary for post-tetanic potentiation, a form of plasticity thought to underlie short-term memory

  3. a new mechanism by which PKC-beta activation promotes EC dysfunction caused by the de-regulation of the IL-18 (show IL18 Proteins)/IL-18BP (show IL18BP Proteins) pathway, leading to increased VCAM-1 (show VCAM1 Proteins) expression, monocyte/macrophage adhesion, and accelerated atherosclerotic plaque formation in diabetes

  4. These results demonstrate the importance of PKCbetaII in chronic lymphocytic leukemia-like disease progression and suggest a role for PKCalpha (show PKCa Proteins) subversion in creating permissive conditions for leukemogenesis.

  5. PKCbeta2 inhibition protects mice from gut (show GUSB Proteins) ischemia-reperfusion injury by suppressing the adaptor p66(Shc)-mediated oxidative stress and subsequent apoptosis.

  6. PKC-alpha (show PKCa Proteins) and -betaIotaIota are the predominant isoforms in the developing optic pathway, whereas PKC-epsilon (show PRKCE Proteins) is the major form in the chiasmatic neurons.

  7. STAT3 (show STAT3 Proteins) bound to previously undescribed negative regulatory elements within the promoter of PRKCB, which encodes PKCbetaII.

  8. These findings indicate that the identity of the calcium-dependent PKCbeta that mediates PTP controls the mechanism and functional consequences of Posttetanic potentiation.

  9. The activation of protein kinase C beta (PRKCB), negatively modulates the mitochondrial energy status and inhibits autophagy.

  10. Identified a set of 22 alternative splicing events that undergo a developmental switch in splicing, and we confirmed that splicing reverts to an embryonic pattern in adult diabetic hearts. PKC isozymes alpha/beta control alternative splicing of these genes.

PKC beta (PRKCB) Protein Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with PKC beta (PRKCB)

  • protein kinase C, beta b (prkcbb)
  • protein kinase C, beta (PRKCB)
  • protein kinase C, beta (Prkcb)
  • A130082F03Rik protein
  • PKC protein
  • PKC-B protein
  • PKC-Beta protein
  • Pkcb protein
  • Prkcb protein
  • Prkcb1 protein
  • Prkcb2 protein
  • zgc:63591 protein

Protein level used designations for Protein Kinase C, beta Proteins (PRKCB)

PKC-beta , protein kinase C beta type , protein kinase C, beta 1 , protein kinase C, beta , PKC-B , protein kinase C, beta 1 polypeptide , protein kinase C beta 2 , protein kinase C beta-II , protein kinase C beta I , protein kinase C beta II , protein kinase C beta 1

393953 Danio rerio
100590939 Nomascus leucogenys
5579 Homo sapiens
397183 Sus scrofa
282325 Bos taurus
18751 Mus musculus
25023 Rattus norvegicus
100037719 Oryctolagus cuniculus
489968 Canis lupus familiaris
416567 Gallus gallus
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