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Browse our anti-RHOC (RHOC) Antibodies

Full name:
anti-Ras Homolog Gene Family, Member C Antibodies (RHOC)
On are 58 Ras Homolog Gene Family, Member C (RHOC) Antibodies from 15 different suppliers available. Additionally we are shipping RHOC Proteins (18) and RHOC Kits (9) and many more products for this protein. A total of 90 RHOC products are currently listed.
AI324259, Arh9, Arhc, CRHOC, H9, LOC100221682, RHOH9
list all antibodies Gene Name GeneID UniProt
RHOC 389 P08134
RHOC 295342  
RHOC 11853 Q62159

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anti-Human RHOC Antibodies:

anti-Rat (Rattus) RHOC Antibodies:

anti-Mouse (Murine) RHOC Antibodies:

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Top referenced anti-RHOC Antibodies

  1. Human Monoclonal RHOC Primary Antibody for WB - ABIN394719 : Wu, Wu, Rosenthal, Rhee, Merajver: Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers. in Cancer 2010 (PubMed)
    Show all 5 references for ABIN394719

  2. Caenorhabditis elegans (C. elegans) Polyclonal RHOC Primary Antibody for IHC, WB - ABIN2786344 : Sousa, Espreafico: Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets. in BMC cancer 2008 (PubMed)

  3. Human Monoclonal RHOC Primary Antibody for ELISA, WB - ABIN513475 : Han, Li, Hu, Yu, Zheng, Guo, Zheng, Yi, Zhou: Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation. in Endocrinology 2010 (PubMed)

  4. Human Monoclonal RHOC Primary Antibody for IF, ELISA - ABIN513476 : Saito, Ohmasa, Shomori, Dimitriadis, Ohiwa, Shimizu, Tsounapi, Kinoshita, Satoh: Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions. in Molecular and cellular biochemistry 2011 (PubMed)

  5. Human Polyclonal RHOC Primary Antibody for IHC (p), WB - ABIN658026 : Jiang, Liu, Kolokythas, Yu, Wang, Heidbreder, Shi, Zhou: Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. in International journal of cancer. Journal international du cancer 2010 (PubMed)

More Antibodies against RHOC Interaction Partners

Human Ras Homolog Gene Family, Member C (RHOC) interaction partners

  1. we demonstrated that the inactivation of the RHOC/AKT (show AKT1 Antibodies)/MAPK (show MAPK1 Antibodies) pathway was involved in the tumor-suppressive functions of HOXD10 (show HOXD10 Antibodies) in cholangiocellular carcinoma .

  2. found that miR (show MLXIP Antibodies)-10b induced HCC (show FAM126A Antibodies) cell invasion and migration by modulating the HOXD10 (show HOXD10 Antibodies) target gene RhoC, uPAR (show PLAUR Antibodies), MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) expression

  3. Smart particles encapsulating the scrambled siRNA sequence did not affect RhoC protein expression.

  4. Depletion of the kinases ROCK1 (show ROCK1 Antibodies) and ROCK2 (show ROCK2 Antibodies), two known RhoC downstream effectors, similarly decreases cancer interaction with ECs

  5. Results identify RhoC as a prominent binding partner of RhoGDI2 (show ARHGDIB Antibodies) and show that RhoGDI2 (show ARHGDIB Antibodies) modulates RhoC activity in cells promoting lung colonization of bladder cancer cells.

  6. Inhibition of ovarian epithelial carcinoma tumorigenesis and progression by miR106b proceeds through the RhoC pathway.

  7. MiR (show MLXIP Antibodies)-93-5P may inhibit EOC tumorigenesis and progression by targeting RhoC.

  8. miR (show MLXIP Antibodies)-509 has a critical role in brain metastasis of breast cancer by modulating the RhoC-TNF-alpha (show TNF Antibodies) network.

  9. RhoC protein may upregulate VEGF expression, thereby promoting tumor angiogenesis in esophageal squamous cell carcinoma.

  10. This is the first report in HNSCC demonstrating the role RhoC plays in mediating EGF (show EGF Antibodies)-stimulated migration and invasion by down-regulating the PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies) pathway and E-cadherin (show CDH1 Antibodies) expression.

Mouse (Murine) Ras Homolog Gene Family, Member C (RHOC) interaction partners

  1. Inhibition of ovarian epithelial carcinoma tumorigenesis and progression by miR106b proceeds through the RhoC pathway.

  2. RHOC and RAB38 (show RAB38 Antibodies) are dispensable for osteoclast function.

  3. A p27(kip1 (show CDKN1B Antibodies))-binding protein, p27RF-Rho (show LAMTOR1 Antibodies), promotes cancer metastasis via activation of RhoA (show RHOA Antibodies) and RhoC.

  4. We found that both RhoA and RhoC, but not RhoB, were required for initiation of centrosome duplication, and overactivation of RhoA, as well as RhoC, but not RhoB, promoted centrosome duplication and centrosome amplification.

  5. RhoC has a role in metastasis of lung cancer in mice

  6. loss of RhoC does not affect tumor development but decreases tumor cell motility and metastatic cell survival leading to a drastic inhibition of metastasis

  7. RhoC promotes melanoma progression via separate mechanisms that regulate the PI3K/Akt (show AKT1 Antibodies) pathway and the ROCK signaling pathway.

RHOC Antigen Profile

Antigen Summary

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with RHOC

  • ras homolog family member C (rhoc) antibody
  • ras homolog family member C (RHOC) antibody
  • ras homolog gene family, member C (LOC100221682) antibody
  • ras homolog family member C (Rhoc) antibody
  • ras homolog gene family, member C (Rhoc) antibody
  • ras homolog gene family, member C (RHOC) antibody
  • AI324259 antibody
  • Arh9 antibody
  • Arhc antibody
  • CRHOC antibody
  • H9 antibody
  • LOC100221682 antibody
  • RHOH9 antibody

Protein level used designations for RHOC

ras homolog gene family, member C , rho-related GTP-binding protein RhoC , RAS-related homolog 9 , oncogene RHO H9 , rho cDNA clone 9 , rhoC GTPase , small GTP binding protein RhoC , SIG-61 , aplysia ras-related homolog 9 (RhoC) , ras homolog 9 (RhoC) , silica-induced gene 61 protein , GTP-binding protein , GTPase cRhoC

379326 Xenopus laevis
483218 Canis lupus familiaris
549323 Xenopus (Silurana) tropicalis
100172158 Pongo abelii
100221682 Taeniopygia guttata
389 Homo sapiens
295342 Rattus norvegicus
11853 Mus musculus
513152 Bos taurus
395869 Gallus gallus
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