Browse our TCF7 Proteins (TCF7)

Full name:
Transcription Factor 7 (T-Cell Specific, HMG-Box) Proteins (TCF7)
On are 4 Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) Proteins from 2 different suppliers available. Additionally we are shipping TCF7 Antibodies (110) and TCF7 Kits (1) and many more products for this protein. A total of 126 TCF7 products are currently listed.
AI465550, TCF-1, Tcf1
list all proteins Gene Name GeneID UniProt
TCF7 6932 P36402
Rat TCF7 TCF7 363595  
TCF7 21414 Q00417

Show all synonyms

TCF7 Proteins (TCF7) by Origin

Select your origin of interest

More Proteins for TCF7 Interaction Partners

Human Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) interaction partners

  1. High expression of TCF7 is associated with osteosarcoma.

  2. Findings indicate that breast cancer cells with a hyperactive AF1q (show MLLT11 Proteins)/TCF7/CD44 (show CD44 Proteins) regulatory axis in the primary sites may represent "metastatic founder cells" which have invasive properties.

  3. TCF7 plays critical roles in lung diseases [review]

  4. Tcf7 levels are lower in islets taken from patients with type 2 diabetes. Knockdown of TCF7 in islets impairs the cytoprotective respo (show GIP Proteins)nsiveness to GIP and enhances the magnitude of apoptotic injury.

  5. Capsaicin-induced apoptosis in pancreatic cancer cells was associated with inhibition of beta-catenin (show CTNNB1 Proteins) signaling due to the dissociation of beta-catenin (show CTNNB1 Proteins)/TCF-1 (show HNF1A Proteins) complex and the process was orchestrated by STAT-3 (show STAT3 Proteins).

  6. we show that TCF7 is a direct target of miR (show MLXIP Proteins)-34a in prostate cancer that has metastasized to the bone

  7. induction of expression activates the Wnt (show WNT2 Proteins) signaling pathway, leading to priming of liver cancer stem cells self-renewal and tumor propagation

  8. RUNX2 (show RUNX2 Proteins) signaling pathways with their partners TCF7 and FGFR1 (show FGFR1 Proteins)/2 may not be involved in CCD (show RUNX2 Proteins) pathogenesis

  9. Results suggest ivermectin as therapeutic WNT protein-TCF (show HNF4A Proteins) transcription factor pathway response blocker to treat WNT (show WNT2 Proteins)-TCF (show HNF4A Proteins)-dependent diseases including multiple cancers.

  10. miRNAs inhibited the expression of the luciferase reporter constructs containing 3'UTRs of these genes and downregulated protein expression of TERT (show TERT Proteins) and the TCF7 transcription factor, which mediates the canonical Wnt (show WNT2 Proteins) pathway.

Mouse (Murine) Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) interaction partners

  1. Tcf7 levels are lower in islets taken from diabetic mice. Knockdown of TCF7 in islets impairs the cytoprotective responsiveness to GIP (show GIP Proteins) and enhances the magnitude of apoptotic injury.

  2. TCF-1-deficient CD4+ CD8+ double positive thymocytes fail to undergo TCR alpha Valpha14-Jalpha18 rearrangement and produce significantly fewer Natural killer T cells.

  3. The data suggest that miR (show MLXIP Proteins)-24 participates in osteogenic differentiation by targeting and regulating Tcf-1 (show HNF1A Proteins) expression in osteoblastic cells.

  4. this study proposes a regulatory role for TCF7 in limiting access to the Treg lineage

  5. Our results support a critical role for miR (show MLXIP Proteins)-22-3p and its target, Tcf7, in the pathogenesis of diabetes by upregulating gluconeogenesis.

  6. TCF-1 (show HNF1A Proteins) was essential for both the initiation of T(FH) differentiation and the effector function of differentiated T(FH) cells during acute viral infection. TCF-1 (show HNF1A Proteins) promoted Bcl-6 (show BCL6 Proteins) expression but repressed Blimp1 (show PRDM1 Proteins) expression.

  7. Chromatin immunoprecipitation sequencing revealed the transcription factor Tcf7 and the chemokine receptor (show CCR1 Proteins) Ccr7 (show CCR7 Proteins) as Foxo1 (show FOXO1 Proteins)-bound target genes, which have critical functions in central-memory T cell differentiation and trafficking.

  8. Our data support that the loss of Tcf7 diminishes hematopoietic stem cell function.

  9. TCF-1 (show HNF1A Proteins) mediates repression of Notch (show NOTCH1 Proteins) pathway in T lineage-committed early thymocytes.

  10. These results are reminiscent of the critical roles of TCF-1 (show HNF1A Proteins) in early T cell development.

TCF7 Protein Profile

Protein Summary

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF7

  • transcription factor 7 (T-cell specific, HMG-box) (TCF7)
  • transcription factor 7 (T-cell specific, HMG-box) (Tcf7)
  • transcription factor 7, T cell specific (Tcf7)
  • AI465550 protein
  • TCF-1 protein
  • Tcf1 protein

Protein level used designations for TCF7

T-cell-specific transcription factor 1 , transcription factor 7 , transcription factor 7, T-cell specific , T cell factor-1 , T-cell factor 1 , TCF-7

6932 Homo sapiens
481506 Canis lupus familiaris
782690 Bos taurus
363595 Rattus norvegicus
21414 Mus musculus
Selected quality suppliers for TCF7 Proteins (TCF7)
Did you look for something else?