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|Application / Reactivity||Human|
|ChIP DNA-Sequencing (ChIPSeq)||2 Antibodies|
|Chromatin Immunoprecipitation (ChIP)||2 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||1 Antibodies|
|Immunohistochemistry (IHC)||5 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||3 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Western Blotting (WB)||28 Antibodies|
|Antigen||Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) Antibodies|
|Epitope||AA 561-588, C-Term Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-TCF7L1 AntibodyTarget Details TCF7L1 Application Details Handling Images
|Sequence||SFPATLHAHQ ALPVLQAQPL SLVTKSAH|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Transcription factor 7-like 1(TCF7L1) detection. Tested with WB, IHC-P in Human.
Gene Name: transcription factor 7 like 1
Protein Name: Transcription factor 7-like 1
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human TCF7L1 (561-588aa SFPATLHAHQALPVLQAQPLSLVTKSAH), different from the related mouse sequence by one amino acid.|
Target Details TCF7L1Product Details anti-TCF7L1 Antibody Application Details Handling Images back to top
|Alternative Name||TCF7L1 (TCF7L1 Antibody Abstract)|
|Background||Transcription factor 7-like 1 (T-cell specific, HMG-box), also known as TCF7L1, is a human gene. This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.|
|Research Area||Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Transcription Factors, Wnt, Wnt Signaling|
|Pathways||WNT Signaling, Stem Cell Maintenance|
Application DetailsProduct Details anti-TCF7L1 Antibody Target Details TCF7L1 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-TCF7L1 Antibody Target Details TCF7L1 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
ImagesProduct Details anti-TCF7L1 Antibody Target Details TCF7L1 Application Details Handling back to top