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Browse our TCF7L1 Proteins (TCF7L1)

Full name:
Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) Proteins (TCF7L1)
On www.antibodies-online.com are 3 Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) Proteins from 2 different suppliers available. Additionally we are shipping TCF7L1 Antibodies (30) and many more products for this protein. A total of 35 TCF7L1 products are currently listed.
Synonyms:
bHLHb21, TCF-3, TCF3, tcf3c, tcf3d, xtcf3
list all proteins Gene Name GeneID UniProt
TCF7L1 21415 Q9Z1J1
TCF7L1 83439 Q9HCS4
Rat TCF7L1 TCF7L1 312451  

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TCF7L1 Proteins (TCF7L1) by Origin

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More Proteins for TCF7L1 Interaction Partners

Mouse (Murine) Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) interaction partners

  1. report the identification of two independent missense variants in human TCF7L1, p.R92P and p.R400Q, in a cohort of patients with forebrain and/or pituitary defects

  2. The authors find that downstream of glycogen synthase kinase 3 (show GSK3a Proteins) inhibition, elevated cMyc (show MYC Proteins) and beta-catenin (show CTNNB1 Proteins) act in parallel to reduce transcription and DNA binding, respectively, of the transcriptional repressor Tcf7l1.

  3. Sox4 and Tcf7l1 form a functional axis that promotes the progression of BCR-ABL (show ABL1 Proteins)-positive acute lymphoblastic leukemia.

  4. The role of Tcf7l1 in mammals is to inhibit the gene regulatory network to ensure the coordination of lineage specification with the dynamic cellular events occurring during gastrulation.

  5. results establish TCF7L1 as a transcriptional hub coordinating cell-cell contact with the transcriptional repression required for adipogenic competency

  6. Tcf3-/- embryos proceed through gastrulation to form mesoderm, but they develop expanded and often duplicated axial mesoderm structures, including nodes and notochords.

  7. E2A (show TCF3 Proteins)-PBX1 (show PBX1 Proteins) interacts directly with the KIX domain of CBP/p300 (show CREBBP Proteins) in the induction of proliferation in primary hematopoietic cells

  8. Tcf3-mediated control of Nanog levels allows stem cells to balance the creation of lineage-committed and undifferentiated cells

  9. These data suggest that in the absence of Wnt (show WNT2 Proteins) signals, Tcf3 may function in skin SCs (show TWIST1 Proteins) to maintain an undifferentiated state and, through Wnt (show WNT2 Proteins) signaling, directs these cells along the hair lineage.

  10. Suggest role for Tcf3 in Wnt (show WNT2 Proteins) signaling mediated fetal intestinal villus morphogenesis.

Human Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) interaction partners

  1. report the identification of two independent missense variants in human TCF7L1 (show TCF3 Proteins), p.R92P and p.R400Q, in a cohort of patients with forebrain and/or pituitary defects

  2. Data indicate that median methylation levels of BCAN (show BCAN Proteins), HOXD1 (show HOXD1 Proteins), KCTD8 (show KCTD8 Proteins), KLF11 (show KLF11 Proteins), NXPH1 (show NXPH1 Proteins), POU4F1 (show POU4F1 Proteins), SIM1 (show SIM1 Proteins), and TCF7L1 (show TCF3 Proteins) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.

  3. No difference in nuclear beta-catenin (show CTNNB1 Proteins) signal intensity was found, which may be caused by an alteration in Wnt (show WNT2 Proteins) pathway in microsatellite stable sporadic tumors by unknown mechanisms leading to lower TCF-3 (show TCF3 Proteins), 4 protein expression.

TCF7L1 Protein Profile

Protein Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.

Alternative names and synonyms associated with TCF7L1

  • transcription factor 7 like 1 (T cell specific, HMG box) (Tcf7l1)
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (TCF7L1)
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (Tcf7l1)
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (tcf7l1-a)
  • bHLHb21 protein
  • TCF-3 protein
  • TCF3 protein
  • tcf3c protein
  • tcf3d protein
  • xtcf3 protein

Protein level used designations for TCF7L1

HMG box transcription factor 3 , T-cell factor 3 , mTCF-3 , transcription factor 3 , transcription factor 7-like 1 , transcription factor 7-like 1 (T-cell specific, HMG box) , transcription factor 7-like 2 (T-cell specific, HMG box) , HMG box transcription factor 3-A , TCF-3-A , transcription factor 7-like 1-A , transcription factor XTCF-3b , xTcf-3

GENE ID SPECIES
21415 Mus musculus
83439 Homo sapiens
312451 Rattus norvegicus
397863 Xenopus laevis
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