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Browse our anti-TLE1 (TLE1) Antibodies

Full name:
anti-Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) Antibodies (TLE1)
On www.antibodies-online.com are 96 Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1) Antibodies from 15 different suppliers available. Additionally we are shipping TLE1 Proteins (4) and many more products for this protein. A total of 105 TLE1 products are currently listed.
Synonyms:
C230057C06Rik, esg, esg1, esg2, esg3, Estm14, Grg1, grg2, grg3, tle3, tle3a, Tle4l, Xesg1, xgrg3
list all antibodies Gene Name GeneID UniProt
TLE1 362533  
TLE1 7088 Q04724
TLE1 21885 Q62440

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anti-Rat (Rattus) TLE1 Antibodies:

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anti-Mouse (Murine) TLE1 Antibodies:

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Top referenced anti-TLE1 Antibodies

  1. Human Polyclonal TLE1 Primary Antibody for EIA, WB - ABIN955230 : Ali, Zaidi, Dobson, Shakoori, Lian, Stein, van Wijnen, Stein: Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN955230

  2. Chicken Polyclonal TLE1 Primary Antibody for WB - ABIN2779588 : Dayyani, Wang, Yeh, Ahn, Tobey, Zhang, Bernstein, Peterson, Sweetser: Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival. in Blood 2008 (PubMed)

More Antibodies against TLE1 Interaction Partners

Human Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1) interaction partners

  1. Data suggest TLE1 is highly expressed in macrophages cultured in vitro, in macrophages of atherosclerotic plaques, and in macrophages of visceral adipose tissue from obese women; expression of TLE1 is up-regulated upon macrophage activat (show IL4 Antibodies)ion.

  2. TLE1 has a role in regulating epithelial-to-mesenchymal transition in A549 cells through its repressive effect on E-cadherin (show CDH1 Antibodies)

  3. There was no difference in TLE-1 staining between different subtypes of synovial sarcoma

  4. GrG1 is involved in pancreatic cell differentiation, establishing a monohormonal beta cell identity. Grg1 is the predominant Groucho expressed in human beta-cells but acts functionally similarly to Grg3.

  5. TCF (show HNF4A Antibodies)/TLE tetramer complex promotes structural transitions of chromatin to mediate repression.

  6. signaling and increases the expression (show NOTCH1 Antibodies)of recombinant recognition sequence binding protein at the Jkappa site (RBP-J) and transducin-like enhancer of Split (show RBPJ Antibodies)(TLE).

  7. Although molecular confirmation is the diagnostic gold standard for synovial sarcoma, TLE1, in view of its high sensitivity may be a useful marker within the optimal IHC panel comprising EMA (show ETFA Antibodies), BCL2 (show BCL2 Antibodies), MIC2, CD34 (show CD34 Antibodies) and CK7 (show KRT7 Antibodies)

  8. TLE1 is selectively upregulated in invasive breast tumors relative to noninvasive ductal carcinoma in situ and normal mammary epithelial tissues.

  9. TLE1, is a necessary transcriptional component of the ER complex, where it facilitates ER-chromatin interactions.

  10. Epistatic and biological interactions between TLE1 and NOD2 (show NOD2 Antibodies) are involved in inflammatory bowel disease pathogenesis.

Mouse (Murine) Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1) interaction partners

  1. Data suggest that Tle1 is highly expressed in activated macrophages cultured in vitro; expression of Tle1 is low in resting macrophages and is up-regulated upon macrophage activation (here, stimulated with recombinant human interleukin-4 (show IL4 Antibodies)).

  2. Loss of Tle1 not only results in increased phosphorylation and activation of proinflammatory NF-kappaB but also results in decreased Hes1 (hairy and enhancer of split-1), a negative regulator of inflammation in macrophages

  3. TLE1/TLE3-NuRD corepressor complex facilitates Tbx20 (show TBX20 Antibodies)-dependent transcriptional repression.

  4. Data indicate that cAMP activates Notch (show NOTCH1 Antibodies) signaling and increases the expression of recombinant recognition sequence binding protein at the Jkappa site (RBP-J (show RBPJ Antibodies)) and transducin (show GNAT1 Antibodies)-like enhancer of Split (TLE).

  5. Studies suggest that TLE1 and TLE3 might also play roles independent of HESX1 (show HESX1 Antibodies) by interacting with other transcription factors like PROP1 (show PROP1 Antibodies).

  6. Grg1-S may operate in conjunction with beta-catenin (show CTNNB1 Antibodies) and Tcf (show HNF4A Antibodies) factors to regulate vertebrate gut (show GUSB Antibodies) epithelial cell differentiation

  7. Grg6 (show TLE6 Antibodies) interferes with the binding of Gro (show CXCL1 Antibodies)/TLE1 to BF-1 (show FOXG1 Antibodies) and does not repress transcription when targeted to DNA.

  8. Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1 (show EPHX1 Antibodies), repressor peptides

TLE1 Antigen Profile

Antigen Summary

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Alternative names and synonyms associated with TLE1

  • transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (Tle1) antibody
  • transducin-like enhancer protein 1 (Smp_150080) antibody
  • transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1) antibody
  • transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (tle1) antibody
  • transducin-like enhancer of split 1, homolog of Drosophila E(spl) (Tle1) antibody
  • transducin-like enhancer of split 2 (E(sp1) homolog) (tle2) antibody
  • C230057C06Rik antibody
  • esg antibody
  • esg1 antibody
  • esg2 antibody
  • esg3 antibody
  • Estm14 antibody
  • Grg1 antibody
  • grg2 antibody
  • grg3 antibody
  • tle3 antibody
  • tle3a antibody
  • Tle4l antibody
  • Xesg1 antibody
  • xgrg3 antibody

Protein level used designations for TLE1

transducin-like enhancer of split 1 , transducin-like enhancer protein 1 , novel protein similar to vertebrate transducin-like enhancer family (E(sp1) homolog Drosophila) , e(Sp1) homolog , enhancer of split groucho 1 , enhancer of split groucho-like protein 1 , transducin-like enhancer of split 1, homolog of Drosophila E(sp1) , grg-1 , groucho-related protein 1 , transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like , enhancer of split groucho , transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) , transducin-like enhancer of split 3 (E(sp1) homolog) a

GENE ID SPECIES
362533 Rattus norvegicus
8346165 Schistosoma mansoni
427450 Gallus gallus
564019 Danio rerio
7088 Homo sapiens
21885 Mus musculus
398072 Xenopus laevis
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