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Browse our anti-TLE4 (TLE4) Antibodies

Full name:
anti-Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) Antibodies (TLE4)
On www.antibodies-online.com are 78 Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) Antibodies from 16 different suppliers available. Additionally we are shipping and and many more products for this protein. A total of 89 TLE4 products are currently listed.
Synonyms:
5730411M05Rik, AA792082, Bce-1, Bce1, E(spI), ESG, esg4, Esp2, ESTM13, ESTM14, grg4, gro, NV17443, TLE4, X83332, X83333, XGrg-4, Xgrg4, XTCF-4, Xtle4

Most Popular Reactivities for anti-TLE4 (TLE4) Antibodies

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anti-Human TLE4 Antibodies:

anti-Rat (Rattus) TLE4 Antibodies:

anti-Mouse (Murine) TLE4 Antibodies:

All available anti-TLE4 Antibodies

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Top referenced anti-TLE4 Antibodies

  1. Chicken Polyclonal TLE4 Primary Antibody for IHC, WB - ABIN2779602 : Dayyani, Wang, Yeh, Ahn, Tobey, Zhang, Bernstein, Peterson, Sweetser: Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival. in Blood 2008 (PubMed)

  2. Human Polyclonal TLE4 Primary Antibody for ELISA, WB - ABIN1533833 : Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: DNA sequence and analysis of human chromosome 9. ... in Nature 2004 (PubMed)

  3. Human Polyclonal TLE4 Primary Antibody for EIA, WB - ABIN955232 : Heimbucher, Murko, Bajoghli, Aghaallaei, Huber, Stebegg, Eberhard, Fink, Simeone, Czerny: Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors. in Molecular and cellular biology 2006 (PubMed)

More Antibodies against TLE4 Interaction Partners

Human Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) interaction partners

  1. PPM1B (show PPM1B Antibodies) interacts with Groucho 4 and is localized to DNA in a Groucho-dependent manner, and phosphatase activity is required for transcriptional silencing.

  2. Groucho related gene Grg4 robustly activates the expression of a BMP reporter gene, as well as enhancing and sustaining the upregulation of the endogenous Id1 (show ID1 Antibodies) gene induced by BMP7 (show BMP7 Antibodies).

  3. Displacing coactivators CREB-binding protein (show CREBBP Antibodies)/p300 (show EP300 Antibodies) while promoting the recruitment of a corepressor, Grg4.

  4. Grg4 recruits the arginine methyltransferase PRMT5 (show PRMT5 Antibodies) to chromatin resulting in symmetric H4R3 dimethylation.

  5. germ cell-specific RBMY and hnRNP G-T proteins were more efficient in stimulating TLE4-T incorporation than somatically expressed hnRNP G protein.

  6. Gbx2 (show GBX2 Antibodies) and Otx2 (show OTX2 Antibodies) interact with the WD40 domain (show DCAF12L2 Antibodies) of Groucho/Tle corepressors

  7. Knockdown of TLE1 (show TLE1 Antibodies) or TLE4 levels increased the rate of cell division of the AML1 (show RUNX1 Antibodies)-ETO (show RUNX1T1 Antibodies)-expressing Kasumi-1 cell line, whereas forced expression of either TLE1 (show TLE1 Antibodies) or TLE4 caused apoptosis and cell death.

Xenopus laevis Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) interaction partners

  1. Results identify the transcriptional co-repressor xTLE1/Groucho as an EphrinB1 (show EFNB1 Antibodies) interacting protein.

  2. The localized activation of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling, which converts Tcf (show HNF4A Antibodies) from a repressor to an activator, is required for the establishment of dorsal-ventral patterning in the prospective diencephalon.

  3. Bowline is a novel protein interacting with Groucho/TLE and may play a role in somitogenesis

Mouse (Murine) Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) interaction partners

  1. Tle4 KO mice are runted, have defects in bone development, bone marrow aplasia. Have leukocytopenia, b-cell lymphoma and reductions in stem cells by 2 weeks. Die by 4 weeks.

  2. TLE3/4 activity is essential for early differentiation where it acts to suppress the pluripotency network, allowing for the initiation of lineage specific gene expression programs

  3. Blimp1 (show PRDM1 Antibodies)-dependent recruitment of Tle4 to the Ifng (show IFNG Antibodies) locus causes epigenetic silencing of the expression of the Ifng (show IFNG Antibodies) gene in anergic TH1 (show HAND1 Antibodies) cells.

  4. Gbx2 (show GBX2 Antibodies) and Otx2 (show OTX2 Antibodies) interact with the WD40 domain (show DCAF12L2 Antibodies) of Groucho/Tle corepressors

  5. Grg4 is an interacting partner for Cux1 (show CUX1 Antibodies) and suggest a mechanism of p27(kip1 (show CDKN1B Antibodies)) repression by Cux1 (show CUX1 Antibodies) during kidney development.

TLE4 Antigen Profile

Antigen Summary

Transcriptional corepressor

Alternative names and synonyms associated with TLE4

  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (TLE4) antibody
  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (LOC100229224) antibody
  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (Tle4) antibody
  • transducin-like enhancer of split 4 (E(sp1) homolog) (tle4) antibody
  • transducin-like enhancer of split 4, homolog of Drosophila E(spl) (Tle4) antibody
  • 5730411M05Rik antibody
  • AA792082 antibody
  • Bce-1 antibody
  • Bce1 antibody
  • E(spI) antibody
  • ESG antibody
  • esg4 antibody
  • Esp2 antibody
  • ESTM13 antibody
  • ESTM14 antibody
  • grg4 antibody
  • gro antibody
  • NV17443 antibody
  • TLE4 antibody
  • X83332 antibody
  • X83333 antibody
  • XGrg-4 antibody
  • Xgrg4 antibody
  • XTCF-4 antibody
  • Xtle4 antibody

Protein level used designations for TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) , transducin-like enhancer protein 4 , transducin-like enhancer protein 4-like , B lymphocyte gene 1 , Protein BCE-1 , enhancer of split groucho 4 , transducin-like enhancer of split 4, homolog of Drosophila E(sp1) , transducin-like enhancer of split 4, E(spl) homolog , transducin-like enhancer of split 4, homolog of Drosophila E(spl) , Groucho-related gene 4 , groucho protein , groucho-related gene 4 , transducin-like enhancer of split 4 , grg-4 , groucho-related protein 4

GENE ID SPECIES
464544 Pan troglodytes
706619 Macaca mulatta
100117159 Nasonia vitripennis
100229224 Taeniopygia guttata
100462498 Pongo abelii
7091 Homo sapiens
25565 Rattus norvegicus
374080 Gallus gallus
508893 Bos taurus
476317 Canis lupus familiaris
399397 Xenopus laevis
21888 Mus musculus
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