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Browse our TLE6 Proteins (TLE6)

Full name:
Transducin-Like Enhancer of Split 6 (E(sp1) Homolog, Drosophila) Proteins (TLE6)
On www.antibodies-online.com are 3 Transducin-Like Enhancer of Split 6 (E(sp1) Homolog, Drosophila) (TLE6) Proteins from 2 different suppliers available. Additionally we are shipping TLE6 Antibodies (23) and many more products for this protein. A total of 29 TLE6 products are currently listed.
Synonyms:
1810057E06Rik, Grg6
list all proteins Gene Name GeneID UniProt
TLE6 79816 Q9H808
TLE6 114606 Q9WVB3

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TLE6 Proteins (TLE6) by Origin

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More Proteins for TLE6 Interaction Partners

Human Transducin-Like Enhancer of Split 6 (E(sp1) Homolog, Drosophila) (TLE6) interaction partners

  1. In this first report of a human defect in a member of the subcortical maternal subcritical maternal complex, we show that the TLE6 mutation is gender-specific and leads to the earliest known human embryonic lethality phenotype

  2. transcriptional programmes regulated by FOXG1 (show FOXG1 Proteins) and Groucho/TLE are important for BTIC-initiated brain tumour growth, implicating FOXG1 (show FOXG1 Proteins) and Groucho/TLE in GBM tumourigenesis

  3. Expression of Tle6-like in colon cancer cells increased cell proliferation, colony-formation, cell migration, and xenograft tumorgenicity.

Mouse (Murine) Transducin-Like Enhancer of Split 6 (E(sp1) Homolog, Drosophila) (TLE6) interaction partners

  1. TLE6 stabilizes the subcortical maternal complex (SCMC). SCMC is required for formation of the cytoplasmic F-actin meshwork that controls the central position of the spindle and ensures symmetric division.

  2. TLE6 localized to the oocyte cortex throughout meiosis in a manner that is spatially and temporally consistent with the localization of critical protein kinase A subunits

  3. Grg6 is expressed in cortical neural progenitor cells, interacts with BF-1 (show FOXG1 Proteins), and plays a role in in cortical neuron development.

  4. Expression of Tle6-like in colon cancer cells increased cell proliferation, colony-formation, cell migration, and xenograft tumorgenicity.

  5. Results describe a subcortical maternal complex, containing Mater, Floped (show OOEP Proteins), TLE6, and Filia (show KHDC3 Proteins), that is essential for preimplantation mouse embryogenesis.

TLE6 Protein Profile

Protein Summary

As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity).

Alternative names and synonyms associated with TLE6

  • transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) (TLE6)
  • transducin-like enhancer of split 6, homolog of Drosophila E(spl) (Tle6)
  • 1810057E06Rik protein
  • Grg6 protein

Protein level used designations for TLE6

transducin-like enhancer protein 6 , Groucho-related protein 6

GENE ID SPECIES
79816 Homo sapiens
114606 Mus musculus
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