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Browse our WNT1 Proteins (WNT1)

Full name:
Wingless-Type MMTV Integration Site Family, Member 1 Proteins (WNT1)
On www.antibodies-online.com are 11 Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) Proteins from 8 different suppliers available. Additionally we are shipping WNT1 Antibodies (103) and WNT1 Kits (12) and many more products for this protein. A total of 136 WNT1 products are currently listed.
Synonyms:
BMND16, Int-1, Int1, OI15, sb:eu647, sw, swaying, WNT-1, WNT1, wnt1-a, Xint-1, Xwnt1, zgc:194464, zgc:194478
list all proteins Gene Name GeneID UniProt
Mouse WNT1 WNT1 22408 P04426
WNT1 7471 P04628
Rat WNT1 WNT1 24881  

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WNT1 Proteins (WNT1) by Origin

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Top referenced WNT1 Proteins

  1. Human WNT1 Protein expressed in Escherichia coli (E. coli) - ABIN413893 : Tawk, Makoukji, Belle, Fonte, Trousson, Hawkins, Li, Ghandour, Schumacher, Massaad: Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 (PubMed)
    Show all 2 references for ABIN413893

More Proteins for WNT1 Interaction Partners

Xenopus laevis Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. maternal Wnt (show WNT2 Proteins)/STOP signaling, but not beta-catenin (show CTNNB1 Proteins) signaling, has a role in cleavage after fertilization and cell cycle progression

  2. sfrp1 (show SFRP1 Proteins) promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt (show WNT2 Proteins) signalling.

  3. analysis of differential role of Axin (show AXIN1 Proteins) RGS (show PITX2 Proteins) domain function in Wnt (show WNT2 Proteins) signaling during anteroposterior patterning and maternal axis formation

  4. Data show taht combined Wnt (show WNT2 Proteins) and Nodal signaling synergistically activates transcription of Spemann organizer genes.

  5. The authors propose that these dual functions of DP1 (show TFDP1 Proteins) can promote and stabilize biphasic Wnt (show WNT2 Proteins)-on and Wnt (show WNT2 Proteins)-off states in response to a gradual gradient of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling to determine differential cell fates.

Mouse (Murine) Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. Decreased expressions of Wnt1 and Wnt5a (show WNT5A Proteins).

  2. we provide unequivocal evidence that epithelial-derived Wnt1 is sufficient to drive interstitial fibrosis in the absence of any injury.

  3. SOXC proteins act cell- and non-cell-autonomously in perichondrocytes and chondrocytes to establish noncanonical WNT (show WNT2 Proteins) signaling crosstalk essential for growth plate induction and control

  4. Data show that elongator protein 3 (Elp3) trigger Wnt-driven tumor initiation in the intestine, and Elp3 deficiency strongly impaired radiation-induced intestinal regeneration.

  5. Fasudil prevents loss of dopamine neurons in the MPTP (show PTPN2 Proteins) mice model of PD through inflammatory inhibition via activation of PI3K/p-Akt (show AKT1 Proteins) and WNT1/Fzd1 (show Fzd1 Proteins)/beta-catenin (show CTNNB1 Proteins) cell signaling pathways.

  6. Wnt (show WNT2 Proteins) has a role in striatal synaptic degeneration and impaired motor behavior in adult mice

  7. Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 (show HMOX1 Proteins) and Wnt1 canonical pathway.

  8. this study gives new insights into transcriptional regulating mechanisms of Wnt (show WNT2 Proteins)-mediated Isl1 (show ISL1 Proteins) expression during cardiomyocyte differentiation.

  9. Data show that bone marrow mesenchymal stem cell (BM-MSC (show MSC Proteins))-generated Wnt1a promotes the dermal papilla's ability to induce hair cycling and regeneration.

  10. modulates neuronal function, hippocampal neurogenesis, and synaptic plasticity and that downregulation of Wnt (show WNT2 Proteins) signaling could be involved in the cognitive decline associated with aging and also with the physiopathology of Alzheimer's disease (AD).

Human Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. MCF7 cells over-expressing both WNT1 and FGF3 (show FGF3 Proteins) show a 3.5-fold increase in mammosphere formation; conditioned media from these cells also promotes stem cell activity in untransfected parental MCF7 and T47D cells, as WNT1 and FGF3 (show FGF3 Proteins) are secreted factors.

  2. IWR-1 has the potential to suppress tumor metastasis by inhibiting Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway as well as survivin (show BIRC5 Proteins) expression

  3. High expression of WNT1 is associated with liver cancer.

  4. Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.

  5. Results suggested that Wnt1-induced MAFK expression promoted cell proliferation in MG63 cells, and that the role of MAFK in osteosarcoma might be closely linked to the Wnt (show WNT2 Proteins) signaling pathway.

  6. Suggest that TGF-beta1 (show TGFB1 Proteins)/Smad (show SMAD1 Proteins) and Wnt (show WNT2 Proteins)/CTNNB1 (show CTNNB1 Proteins) signaling pathways both contribute to pathological scar formation.

  7. Data suggest that fibulin-5 (show FBLN5 Proteins) functions as a metastasis suppressor in lung cancer by modulating tumor microenvironment to suppress Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling.

  8. Paracrine WNT (show WNT2 Proteins) signaling is stimulated by estrogen and progesterone, while autocrine WNT (show WNT2 Proteins) signaling is induced by the embryonic T-box transcription factor TBX3 (show TBX3 Proteins)

  9. Wnt1 promotes CD36 (show CD36 Proteins) expression via activation of PPAR-gamma (show PPARG Proteins) and TCF4 (show TCF4 Proteins).

  10. Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 (show HMOX1 Proteins) and Wnt1 canonical pathway.

Cow (Bovine) Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. Data indicate that Wnt-1 protein is present in postdevelopmental endothelial cells where it associates with cytoskeletal elements and may retain function as a tissue polarity gene.

Zebrafish Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. analysis of differential role of Axin (show AXIN1 Proteins) RGS (show PITX2 Proteins) domain function in Wnt (show WNT2 Proteins) signaling during anteroposterior patterning and maternal axis formation

  2. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  3. wnt1 and wnt10b (show WNT10B Proteins) are required to maintain threshold levels of Pax2.1 and Fgf8 (show FGF8 Proteins) at the midbrain-hindbrain boundary.

  4. novel role for Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling in determining endocardial cell fate

  5. In zebrafish embryos lacking Wnt3a (show WNT3A Proteins), Wnt1 and Wnt10b (show WNT10B Proteins), the expression of engrailed orthologs, pax2a and fgf8 (show FGF8 Proteins) is not maintained after mid-somitogenesis

  6. two Dvl (show DVL2 Proteins)-associated paralogs, Dpr1 (show DACT1 Proteins) and Dpr2 (show DACT2 Proteins), participate in distinct Wnt (show WNT2 Proteins)-dependent developmental processes

  7. Wnt (show WNT2 Proteins)/Axin (show AXIN1 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway has a role in ventral CNS development

  8. The boundary and roof plate expression of wnt1 each contribute to upregulation of proneural and delta gene expression and neurogenesis in non-boundary regions.

  9. Epistatic analyses suggest a possible genetic interaction between Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) and Myostatin (show MSTN Proteins) in regulation of slow and fast twitch muscle myofibrillogenesis

WNT1 Protein Profile

Protein Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Alternative names and synonyms associated with WNT1

  • wingless-type MMTV integration site family, member 1 (WNT1)
  • wingless-type MMTV integration site family, member 1 (wnt1)
  • wingless-related MMTV integration site 1 (Wnt1)
  • wingless-type MMTV integration site family, member 1 (Wnt1)
  • wingless-type MMTV integration site family, member 1 (WNT-1)
  • BMND16 protein
  • Int-1 protein
  • Int1 protein
  • OI15 protein
  • sb:eu647 protein
  • sw protein
  • swaying protein
  • WNT-1 protein
  • WNT1 protein
  • wnt1-a protein
  • Xint-1 protein
  • Xwnt1 protein
  • zgc:194464 protein
  • zgc:194478 protein

Protein level used designations for WNT1

XWnt-1 , protein Wnt-1 , proto-oncogene Int-1 , proto-oncogene Wnt-1 , proto-oncogene protein Wnt-1 , proto-oncogene Int-1 homolog , wingless-type MMTV integration site family, member 1 (oncogene INT1) , Wingless-type MMTV integration site 1 homolog , Wingless-type MMTV integration site 1, homolog , wingless-related MMTV integration site 1 , murine mammary tumor virus integration site , etID22400.23 , wingless-type MMTV integration site family member 1

GENE ID SPECIES
100058859 Equus caballus
373578 Xenopus laevis
22408 Mus musculus
7471 Homo sapiens
24881 Rattus norvegicus
486560 Canis lupus familiaris
540662 Bos taurus
30128 Danio rerio
396160 Gallus gallus
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