Browse our WNT2 Proteins (WNT2)

Full name:
Wingless-Type MMTV Integration Site Family Member 2 Proteins (WNT2)
On are 27 Wingless-Type MMTV Integration Site Family Member 2 (WNT2) Proteins from 6 different suppliers available. Additionally we are shipping WNT2 Antibodies (65) and WNT2 Kits (15) and many more products for this protein. A total of 112 WNT2 products are currently listed.
2610510E18Rik, CG1916, D-wnt-2, Dm-2, Dm DWnt2, Dmel\\CG1916, Dwnt-2, dWnt2, INT1L1, IRP, Mirp, Wnt, wnt-2, WNT2, Wnt2a, Xwnt-2, Xwnt2, ZfWnt2
list all proteins Gene Name GeneID UniProt
Mouse WNT2 WNT2 22413 P21552
WNT2 7472 P09544
Rat WNT2 WNT2 114487  

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WNT2 Proteins (WNT2) by Origin

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Top referenced WNT2 Proteins

  1. Human WNT2 Protein expressed in Wheat germ - ABIN1325356 : Habuchi, Nagai, Sugaya, Atsumi, Stevens, Kimata: Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for 1325356

More Proteins for WNT2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Wingless-Type MMTV Integration Site Family Member 2 (WNT2) interaction partners

  1. We discovered an otk paralog (otk2, CG8964), which is co-expressed with otk throughout embryonic and larval development. Otk and Otk2 bind to each other and form complexes with Frizzled, Frizzled2 (show FZD2 Proteins) and Wnt2, pointing to a function as Wnt (show WNT4 Proteins) co-receptors.

  2. Mutations in Wnt2 alter presynaptic motor neuron morphology and presynaptic protein localization at the neuromuscular junction.

  3. DWnt-2 promotes correct patterning of direct flight muscles through a mechanism that is independent of the attachment site differentiation initiated by stripe.

  4. Data show that Drosophila Naked cuticle (Nkd (show NKD1 Proteins)) engages the nuclear import adaptor Importin-alpha3 (show KPNA4 Proteins) to antagonize Wnt (show WNT4 Proteins)/beta-catenin signaling.

  5. It activates beta-catenin-independent pathway, such as planar cell polarity pathway, calcium signaling. (review)

Mouse (Murine) Wingless-Type MMTV Integration Site Family Member 2 (WNT2) interaction partners

  1. Upregulation of Wnt2 expression enhanced WISP-1 (show WISP1 Proteins) and promoted vascular smooth muscle cell migration and intimal thickening.

  2. Wnt 2 levels were markedly down-regulated by retinoic acid in pancreatic stellar cells and chronic pancreatitis.

  3. We propose that the WNT2/CTNNB1 (show CTNNB1 Proteins) pathway regulates CX43 (show GJA1 Proteins) expression and gap junction intercellular communication in granulosa cells by modulating CTNNB1 (show CTNNB1 Proteins) stability and localization in adherens junctions

  4. Pdgf (show PDGFA Proteins) signaling potentiates Wnt2-Wnt7b (show WNT7B Proteins) signaling to promote high levels of Wnt activity in mesenchymal progenitors that is required for proper development of endoderm-derived organs, such as the lung

  5. Expression of WNT2 in pancreatic cancer cells suppresses anoikis, enhances anchorage-independent sphere formation, and increases metastatic propensity in vivo.

  6. Wnt2 plays strong positive stage-specific role in cardiogenesis through non-canonical Wnt pathway in murine ES cells.

  7. show that Wnt2 signaling is necessary and sufficient for activation of a transcriptional and signaling network critical for smooth muscle specification and differentiation including myocardin/Mrtf-B (show MKL2 Proteins) and the signaling factor Fgf10 (show FGF10 Proteins)

  8. Wnt2 expression is downregulated at lung bud stage in the nitrofen model. Optical projection tomography is potentially a useful approach to visualize both gene expression and morphology during very early stages of lung development.

  9. The canonical WNT signaling pathway is intact in mouse granulosa cells and that WNT2 can act through beta-catenin, likely downstream of FZD9, to regulate DNA synthesis.

  10. Results identify Wnt2 as a novel regulator of dopaminergic progenitors and dopaminergic neuron development.

Human Wingless-Type MMTV Integration Site Family Member 2 (WNT2) interaction partners

  1. High WNT2 expression is associated with Cervical Carcinoma Metastasis.

  2. targeting beta-catenin with lipofection-delivered small interfering RNA oligonucleotide inhibited the proliferation and cell cycle arrest in G0/G1 phase and increased apoptosis of fibroblast cells, accompanied by downregulation of Wnt2 and cyclin D1 as well as the phosphorylation level of glycogen synthase kinase 3 beta in the keloid fibrosis

  3. Genetic polymorphisms in the WNT2 and CTNNB1 genes were closely associated with hepatocellular carcinoma risk and progression in a Chinese Han population

  4. The WNT2 rs39315 G allele was associated with advanced tumor stage in hepatocellular carcinoma.

  5. Wnt2 complements Wnt/beta-catenin (show CTNNB1 Proteins) signaling in regulating colorectal cancer cell proliferation.

  6. Wnt2/beta-catenin (show CTNNB1 Proteins) signaling was involved in stromal-epithelial cells interaction in endometriosis.

  7. High expression of Wnt2 is associated with pancreatic cancer progression promoted by pancreatic stellate cells.

  8. Hypermethylation of WNT2 is associated with colorectal cancer.

  9. The study demonistrated that expressions of Wnt-2 in high-grade brainstem gliomas were significantly higher than that in low-grade brainstem gliomas and normal brain tissues and were positively correlated with the expression of Ki-67 (show MKI67 Proteins).

  10. Decreased placental expression of Wnt2 and increased placental expression of sFRP4 (show SFRP4 Proteins) may be associated with the pathogenesis of severe preeclampsia.

Cow (Bovine) Wingless-Type MMTV Integration Site Family Member 2 (WNT2) interaction partners

  1. WNT2 gene is associated with resistance to paratuberculosis

  2. These data demonstrate for the first time that FSH (show BRD2 Proteins) regulates CTNNB1 (show CTNNB1 Proteins) protein and WNT2 mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT signaling in ovarian steroidogenesis and follicular growth of cattle.

Zebrafish Wingless-Type MMTV Integration Site Family Member 2 (WNT2) interaction partners

  1. show that sequential functions of Wnt2bb and Wnt2 control liver specification and proliferation in zebrafish

WNT2 Protein Profile

Protein Summary

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.

Alternative names and synonyms associated with WNT2

  • Wnt oncogene analog 2 (Wnt2)
  • wingless-type MMTV integration site family member 2 (wnt2)
  • wingless-type MMTV integration site family member 2 (LOC100221216)
  • wingless-type MMTV integration site family member 2 (WNT2)
  • wingless-related MMTV integration site 2 (Wnt2)
  • wingless-type MMTV integration site family member 2 (Wnt2)
  • 2610510E18Rik protein
  • CG1916 protein
  • D-wnt-2 protein
  • Dm-2 protein
  • Dm DWnt2 protein
  • Dmel\\CG1916 protein
  • Dwnt-2 protein
  • dWnt2 protein
  • INT1L1 protein
  • IRP protein
  • Mirp protein
  • Wnt protein
  • wnt-2 protein
  • WNT2 protein
  • Wnt2a protein
  • Xwnt-2 protein
  • Xwnt2 protein
  • ZfWnt2 protein

Protein level used designations for WNT2

CG1916-PA , Wnt2-PA , wingless-type MMTV integration site family member 2 , INT-1-related protein , protein Wnt-2 , Int-1-related protein , int-1-like protein 1 , secreted growth factor , wingless-related MMTV integration site 2 , wingless-type MMTV integration site 2 , protein Wnt-2-like , Protein Wnt-2 , etID309852.18

35975 Drosophila melanogaster
100137508 Takifugu rubripes
100221216 Taeniopygia guttata
100303493 Saccoglossus kowalevskii
612141 Canis lupus familiaris
780953 Monodelphis domestica
100038261 Xenopus (Silurana) tropicalis
100125382 Sus scrofa
22413 Mus musculus
7472 Homo sapiens
114487 Rattus norvegicus
417769 Gallus gallus
493729 Bos taurus
493672 Felis catus
100056092 Equus caballus
100126569 Oryctolagus cuniculus
100126577 Ovis aries
100137034 Pongo abelii
100411308 Callithrix jacchus
463673 Pan troglodytes
30127 Danio rerio
101651785 Echinops telfairi
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