We are preparing the requested document. Please wait, this may take a while...!
|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Immunochromatography (IC)||8 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunofluorescence (IF)||12 Antibodies|
|Immunohistochemistry (IHC)||19 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||12 Antibodies|
|Western Blotting (WB)||64 Antibodies|
|Antigen||Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) Antibodies|
|Epitope||AA 155-184, Center Alternatives|
|Conjugate||This WNT3 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-WNT3 AntibodyTarget Details WNT3 Application Details Handling References for anti-WNT3 Antibody (ABIN658051) Images
|Specificity||This WNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-184 amino acids from the Central region of human WNT3.|
|Predicted Reactivity||Chicken,Mouse (Murine),Xenopus laevis|
|Purification||This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Immunogen||This WNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 AA from the Central region of human WNT3.|
Target Details WNT3Product Details anti-WNT3 Antibody Application Details Handling References for anti-WNT3 Antibody (ABIN658051) Images back to top
|Alternative Name||WNT3 (WNT3 Antibody Abstract)|
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Synonyms: Proto-oncogene Wnt-3,WNT3,INT4
|Molecular Weight||39645 DA|
|Research Area||Cell Signaling, Protein Modifications, Cancer, Cell Structure|
Application DetailsProduct Details anti-WNT3 Antibody Target Details WNT3 Handling References for anti-WNT3 Antibody (ABIN658051) Images back to top
|Application Notes||WB = 1:1000|
|Restrictions||For Research Use only|
HandlingProduct Details anti-WNT3 Antibody Target Details WNT3 Application Details References for anti-WNT3 Antibody (ABIN658051) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
|Storage Comment||WNT3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.|
|Expiry Date||6 months|
References for anti-WNT3 Antibody (ABIN658051)Product Details anti-WNT3 Antibody Target Details WNT3 Application Details Handling Images back to top
Nikopensius, Jagomägi, Krjutskov et al.: "Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 88, Issue 9, pp. 748-56, 2010 (PubMed).
Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).
Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).
ImagesProduct Details anti-WNT3 Antibody Target Details WNT3 Application Details Handling References for anti-WNT3 Antibody (ABIN658051) back to top