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anti-Mouse (Murine) WNT8B Antibodies:
anti-Human WNT8B Antibodies:
anti-Rat (Rattus) WNT8B Antibodies:
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Wnt8b expression is up-regulated in the optic stalk of Foxg1 (show FOXG1 Antibodies)(-/-) mutants before optic fissure closure initiates.
Neuroretina specification requires Six3-mediated suppression of Wnt8b a few hours later at the 6- to 8-somite stage.
Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt (show WNT2 Antibodies) gene expression levels in dorsomedial telencephalon.
these results revealed that wnt8b and fzd3a act in the same genetic pathway to pattern the commissural plate, thereby indirectly regulating the crossing of axons across the rostral midline in the embryonic forebrain of zebrafish.
Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish.
WNT8b and SHH (show SHH Antibodies) mutations and abnormal expressions are present in the peripheral blood of children with sporadic Hirschsprung disease.
Expression and regulation of WNT8B mRNA in human tumor cell lines
WNT8B expression in hepatocyte progenitors derived from human ES cells is due to POU5F1 (OCT3/OCT4 (show POU5F1 Antibodies)) and GATA3 (show GATA3 Antibodies), and WNT8B expression in diffuse-type gastric cancer is due to POU5F1 (show POU5F1 Antibodies) and GATA6 (show GATA6 Antibodies)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
wingless-type MMTV integration site family, member 8B
, protein Wnt-8b-like
, protein Wnt-8b
, wingless-type MMTV integration site family member 8b
, wingless related MMTV integration site 8b