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Wnt9a input is required prior to aorta formation.
the chaperon Wls (show WLS ELISA Kits) and its ligands Wnt9a and Wnt5b (show WNT5B ELISA Kits) are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb (show FRZB ELISA Kits) and Gpc4 (show GPC4 ELISA Kits).
disruption of wls (show WLS ELISA Kits) resulted in a significant loss of craniofacial bone, whereas lack of gpc4 (show GPC4 ELISA Kits), wnt5b (show WNT5B ELISA Kits) and wnt9a resulted in severely delayed endochondral ossification.
These data corroborate the central role for Wnt (show WNT2 ELISA Kits) signaling in vertebrate craniofacial development.
Wnt9a is expressed in the embryonic pancreas and that its deficiency enhances activation of the endocrine transcriptional program and increases the number of endocrine cells at birth.
These studies reveal how carrageenan exposure can lead to transcriptional events in colonic epithelial cells through decline in arylsulfatase B (show ARSB ELISA Kits) activity, with subsequent impact on C4S (show CHST11 ELISA Kits), galectin-3 (show LGALS3 ELISA Kits), Sp1 (show SP1 ELISA Kits), and Wnt9A
The mRNA levels of Wnt3 (show WNT3 ELISA Kits), 6, and 9a were significantly upregulated in the intestinal epithelial cells by Salmonella.
Embryos double-heterozygous for Wnt9a and beta-catenin (show CTNNB1 ELISA Kits) show reduced Ihh (show IHH ELISA Kits) expression.
This manipulation increased one type of sensory hair cell (tall HCs (show HLCS ELISA Kits)) at the expense of another (short HCs (show HLCS ELISA Kits)) that is usually located furthest from the Wnt9a source. The extraneous tall HCs (show HLCS ELISA Kits) that replaced short HCs (show HLCS ELISA Kits) showed some physiological properties and neuronal connections consistent with a fate switch.
Inhibition of WNT (show WNT2 ELISA Kits) signaling by the PORCN (show PORCN ELISA Kits) inhibitor WNT974 reduced metastatic spread of UM-SCC (show CYP11A1 ELISA Kits) cells, especially in UM-SCCs with Notch1 (show NOTCH1 ELISA Kits) deficiency.
Silencing Wnt9A increased the expression of CHST11 (show CHST11 ELISA Kits) in the colonic epithelial cells, and chromatin immunoprecipitation assay demonstrated enhancing effects of Wnt9A siRNA and exogenous BMP4 (show BMP4 ELISA Kits) on the CHST11 (show CHST11 ELISA Kits) promoter
These studies reveal how carrageenan exposure can lead to transcriptional events in colonic epithelial cells through decline in arylsulfatase B (show ARSB ELISA Kits) activity, with subsequent impact on C4S (show CHST11 ELISA Kits), galectin-3 (show LGALS3 ELISA Kits), Sp1 (show PSG1 ELISA Kits), and Wnt9A
Transgenic wnt9a is required for palatal extension wherein the chondrocytes form a proliferative front, undergo morphological change and intercalate to form the ethmoid plate.
Using DirectDNA sequencing analysis, we detected ATBF1 (show ZFHX3 ELISA Kits), CYLD (show CYLD ELISA Kits), PARK2 (show PARK2 ELISA Kits) and WNT9A mutations in stomach and colorectal cancers
Results demonstrated significant up-regulation of WNT-3 (show WNT3 ELISA Kits), WNT-4 (show WNT4 ELISA Kits), WNT-5B (show WNT5B ELISA Kits), WNT-7B (show WNT7B ELISA Kits), WNT-9A, WNT-10A (show WNT10A ELISA Kits), and WNT (show WNT2 ELISA Kits)-16B in patients with CLL compared to normal subjects.
Found clustered with WNT3A (show WNT3A ELISA Kits) on 1q42. .
5'-flanking promoter region was significantly divergent between human WNT9A and rodent Wnt9a genes.
These results suggests the expression level of human Wnt9a in MCF-7 that breast cancer may play a role in adjusting the rate of cellular proliferation.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region.
wingless-type MMTV integration site family, member 9A
, protein Wnt-9a
, protein Wnt-9a-like
, wingless-type MMTV integration site 14
, wingless-type MMTV integration site family, member 14
, wingless related MMTV integration site 9A
, wingless-type MMTV integration site 9A