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WTIP Proteins

(Wilms Tumor 1 Interacting Protein (WTIP))
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.
WTIP Protein (AA 1-430) (Strep Tag) WTIP Protein (AA 1-430) (Strep Tag) WTIP Protein (AA 1-430) (Strep Tag) (ABIN3096372)

Crystallography grade WTIP Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS

WTIP Protein (Myc-DYKDDDDK Tag) WTIP Protein (Myc-DYKDDDDK Tag) WTIP Protein (Myc-DYKDDDDK Tag) (ABIN2735591)

WTIP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

WTIP Proteins by Grade

Find WTIP Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

WTIP Proteins by Origin

Find WTIP Proteins for a variety of species such as anti-Human WTIP. The species listed below are among those available. Click on a link to go to the corresponding products.

WTIP Proteins by Source

Here you will find WTIP Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

WTIP Proteins by Protein Type

Here you can find WTIP Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

WTIP Proteins by Application

Find WTIP Proteins validated for a specific application such as AbP, ELISA, SDS, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular WTIP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3096372
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735591
Quantity 20 μg
Datasheet Datasheet

Aliases for WTIP Proteins

WT1 interacting protein (Wtip) Proteins
WT1 interacting protein (WTIP) Proteins
WT1 interacting protein (wtip) Proteins
Wilms tumor 1 interacting protein (WTIP) Proteins
WT1 interacting protein L homeolog (wtip.L) Proteins
WT1-interacting protein (Wtip) Proteins
RGD1306411 Proteins
si:ch211-79l17.3 Proteins
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