anti-A Kinase (PRKA) Anchor Protein 7 (AKAP7) Antibodies

AKAP7 encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. Additionally we are shipping AKAP7 Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AKAP7 9465 O43687 , Q9P0M2
AKAP7 432442  
AKAP7 361458  
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Top anti-AKAP7 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-AKAP7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate Rabbit Anti-AKAP7 Antibody    Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Membrane, Cytoplasmic Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-AKAP7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Small Intestine Rabbit Anti-AKAP7 Antibody    Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Membrane, Cytoplasmic Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-AKAP7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human brain Rabbit Anti-AKAP7 Antibody    Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Membrane Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AKAP7 Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate AKAP7 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AKAP7 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human brain 100 μL 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with AKAP7 antibody ABIN214084 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-AKAP7 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product ... 100 μL 11 to 14 Days
$727.83
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

More Antibodies against AKAP7 Interaction Partners

Human A Kinase (PRKA) Anchor Protein 7 (AKAP7) interaction partners

  1. AKAP7 expression levels may have clinical utility as a prognostic biomarker for post-stroke blood brain complications

  2. Malonate in the nucleotide-binding site traps human AKAP18-gamma in a novel conformational state.

  3. PKC tethered to AKAP7alpha was less susceptible to inhibition from the ATP-competitive inhibitor Go6976 and the substrate-competitive inhibitor PKC 20-28, but not the activation-competitive inhibitor calphostin C.

  4. Data from studies using recombinant proteins suggest that both AKAP7-gamma and AKAP7-alpha exhibit high-affinity interactions with isoenzymes of PKC (protein kinase C); AKAP7 could dictate PKC localization/function.

  5. AKAP7gamma is the first nuclear AKAP to bind RI and may be responsible for positioning PKA via RI and/or RII to regulate PKA-mediated gene transcription in both somatic cells and oocytes

  6. AKAP15 regulates ENaC via a novel PKA-independent pathway

  7. AKAP18 contains a phosphodiesterase domain that binds AMP.

Mouse (Murine) A Kinase (PRKA) Anchor Protein 7 (AKAP7) interaction partners

  1. Genetic ablation of AKAP7 specifically from dentate granule cells results in disruption of mossy fiber-CA3 pyramidal neuron long-term potentiation directly initiated by cAMP, and the AKAP7 mutant mice are selectively deficient in pattern separation behaviors. The results suggest that the AKAP7/PKA complex in the mossy fiber projections plays an essential role in synaptic plasticity and contextual memory formation.

  2. The results demonstrate that green tea catechins enhance lipolysis in the presence of norepinephrine via a PKA-dependent pathway in 3T3-L1 adipocytes, providing a potential mechanism by which green tea catechins could reduce body fat.

  3. Protein kinase A activation enhances hippocampal mossy fiber glutamatergic transmission.

  4. AKAP7 is not required for regulation of Ca(2+) handling in mouse cardiomyocytes.

  5. AKAP15 co-immunoprecipitates with CaV1.2 and CaV1.3 channels. AKAP15 has overlapping localization with CaV1.2 and CaV1.3 channels in cell bodies and proximal dendrites and is closely co-localized with CaV1.2 channels in punctate clusters.

  6. CaV1.2 channels in DCT-/- myocytes fail to respond to activation of adenylyl cyclase by forskolin, and the localized expression of AKAP15 is reduced

  7. Alterations in cortical synaptic receptors, impairments in sleep continuity, and alterations in sleep oscillations in R(AB) mice imply that PKA is involved not only in synaptic plasticity and memory storage but also in the regulation of sleep/wake states.

  8. AKAP7gamma is the first nuclear AKAP to bind RI and may be responsible for positioning PKA via RI and/or RII to regulate PKA-mediated gene transcription in both somatic cells and oocytes

AKAP7 Antigen Profile

Protein Summary

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with AKAP7

  • A-kinase anchoring protein 7 (AKAP7) antibody
  • A-kinase anchoring protein 7 L homeolog (akap7.L) antibody
  • A kinase (PRKA) anchor protein 7 (akap7) antibody
  • A kinase (PRKA) anchor protein 7 (Akap7) antibody
  • A-kinase anchoring protein 7 (Akap7) antibody
  • 6430401D08 antibody
  • AI662165 antibody
  • AKAP-18 antibody
  • AKAP7 antibody
  • Akap15 antibody
  • Akap18 antibody
  • AKAP18d antibody
  • BB170514 antibody
  • MGC83920 antibody

Protein level used designations for AKAP7

A kinase (PRKA) anchor protein 7 , a-kinase anchor protein 7 isoform gamma-like , A-kinase anchor protein 18 kDa , A-kinase anchor protein 7 isoform gamma , A-kinase anchor protein 7 isoforms alpha and beta , A-kinase anchor protein 9 kDa , AKAP 18 , AKAP-7 isoform gamma , AKAP-7 isoforms alpha and beta , PRKA7 isoform gamma , PRKA7 isoforms alpha/beta , A-kinase anchor protein 7 , A-kinase anchor protein 18 , AKAP 9 , AKAP-18 , AKAP-7 isoform alpha , PRKA7 isoform alpha , protein kinase A anchoring protein 7 , protein kinase A-anchoring protein 7 isoform alpha , protein kinase A-anchoring protein 7 isoform gamma , A-kinase anchor protein 7 isoforms delta and gamma , A-kinase anchoring protein 18 ,isoform delta , AKAP-7 isoforms delta and gamma , PRKA7 isoforms delta and gamma , protein kinase A-anchoring protein 7 isoforms delta and gamma

GENE ID SPECIES
426926 Gallus gallus
447759 Xenopus laevis
462998 Pan troglodytes
710509 Macaca mulatta
100379710 Xenopus (Silurana) tropicalis
100432245 Pongo abelii
100601441 Nomascus leucogenys
9465 Homo sapiens
613606 Bos taurus
432442 Mus musculus
361458 Rattus norvegicus
484128 Canis lupus familiaris
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