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ADAMTS19 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family.
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Cow (Bovine) Polyclonal ADAMTS19 Primary Antibody for WB - ABIN610733
Buchert, Schneider, Meskenaite, Adams, Canaani, Baechi, Moelling, Hovens: The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain. in The Journal of cell biology 1999
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The pregnancy loss rate does not appear to be affected by both ADAMTS-13 (show ADAMTS13 Antibodies) and ADAMTS-19.
We found that the AAAAA, AGGAG, and AGGGA haplotypes in ACVR2B (show ACVR2B Antibodies) were associated with susceptibility to Premature Ovarian Failure when they also had at least one CATAG haplotype in ADAMTS19.
Synergistic interactions were detected between SNPs, including a non-synonymous SNP, and diplotypes within IGF2R (show IGF2R Antibodies) and ADAMTS19 which may contribute to POF (show POF1B Antibodies).
Although limited by sample size, this proof-of-principle study's findings reveal ADAMTS19 as a possible candidate gene for premature ovarian failure and thus a larger follow-up study is warranted.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member.
ADAM metallopeptidase with thrombospondin type 1 motif, 19
, A disintegrin and metalloproteinase with thrombospondin motifs 19-like
, a disintegrin and metalloproteinase with thrombospondin motifs 19-like
, A disintegrin and metalloproteinase with thrombospondin motifs 19
, ADAM-TS 19
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19