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Regulator of the canonical Wnt signaling pathway. Additionally we are shipping and and many more products for this protein.
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Data suggest Amer3 activates Wnt (show WNT2 Antibodies) signaling, in contrast to Amer1 (show AMER1 Antibodies)/Amer2 (show AMER2 Antibodies) which inhibit Wnt (show WNT2 Antibodies), suggesting non-redundant role of Amer proteins in regulation of Wnt (show WNT2 Antibodies) pathway. Knockdown of Amer3 reduces Wnt (show WNT2 Antibodies) target gene expression in colorectal cancer cells.
Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity).
APC membrane recruitment protein 3
, family with sequence similarity 123, member C
, protein FAM123C
, family with sequence similarity 123C