anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) Antibodies

The protein encoded by ABCA7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA7 Kits (15) and ABCA7 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCA7 27403 Q91V24
ABCA7 10347 Q8IZY2
ABCA7 299609 Q7TNJ2
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Top anti-ABCA7 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Abca7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Mouse Liver Host:  Rabbit  Target Name:  ABCA7  Sample Tissue:  Mouse Spleen  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of ABCA7 expression in HeLa (A), Raw264.7 (B), mouse liver (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rat Un-conjugated FACS, IHC (p), WB Flow Cytometry: ABCA7 Antibody (7A1-144) [ABIN438226] - Analysis using Azide/BSA FREE version of ABIN438226. Analysis of 6C (red) (negative control HeLa cells) and A7(blue) (ABCA7 expressing HeLa cells) using NB 400-166 at a dilution of 1:3,000. Western Blot: ABCA7 Antibody (7A1-144) [ABIN438226] - Detection of ABCA7 using NB 400-163 at various dilutions in ABCA7 transfected HeLa lysates. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ABCA7 Antibody [NBP2-14250] Staining of human cell line A-431 shows positivity in plasma membrane and golgi apparatus. Immunohistochemistry-Paraffin: ABCA7 Antibody [NBP2-14250] - Staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Mouse Rat PE FACS   100 Tests Log in to see 7 to 9 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ABCA7 in 293 cell lysate with ABCA7 antibody at (A) 1 and (B) 2 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$350.00
Details
Human Rabbit Un-conjugated ICC, IF, ELISA, WB   100 μg Log in to see 15 to 19 Days
$523.71
Details
Mouse Rat Un-conjugated FACS   250 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB Abca7 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 6 to 8 Days
$473.93
Details

ABCA7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABCA7 Antibodies

  1. Cow (Bovine) Polyclonal ABCA7 Primary Antibody for WB - ABIN2781526 : Bamji-Mirza, Li, Najem, Liu, Walker, Lue, Stupak, Chan, Li, Ghani, Yang, Rogaeva, Zhang: Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models. in Journal of Alzheimer's disease : JAD 2016 (PubMed)

More Antibodies against ABCA7 Interaction Partners

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. ABCA7 does not play a significant role in the regulation of cell proliferation or neurogenesis in the adult mouse.

  2. This study demonstrated that novel mechanism underlying how dysfunctions of ABCA7 contribute to the risk for alzheimer disease.

  3. ABCA7 has a role in Alzheimer amyloid processing

  4. Theresults of this study suggested that ABCA7 plays a role in the regulation of Abeta (show APP Antibodies) homeostasis in the brain and that this may be related to altered phagocyte function.

  5. ABCA7 may play a role in T cell proliferation and erythropoeisis in spleen

  6. concluded that statins enhance macrophage phagocytosis through the SREBP-ABCA7 pathway.

  7. Data suggest that extracellular helical apolipoproteins augment ABCA7-associated phagocytosis by stabilizing ABCA7, and show direct enhancement of the host defense system by HDL (show HSD11B1 Antibodies) components.

  8. ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and has a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues

  9. genetic knockdown of ABCA7 in mouse peritoneal macrophages did not affect phospholipid or cholesterol efflux to apoA-I (show APOA1 Antibodies)

  10. ABCA7 plays a novel role in lipid and fat metabolism

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. Study investigated the association between ABCA7 rs3764650 SNP and blood lipid levels in Southern Chinese Han sporadic Alzheimer's disease population, and found GG genotype was a risk factor of sporadic Alzheimer's disease as well as lipid homeostasis.

  2. The primary findings of this report are that abnormal ABCA7 exon 41 splicing is found in the brain of an individual carrying the minor C allele of rs200538373 and that rs200538373 is a functional SNP

  3. rs3764650 ABCA7 is not associated with late-onset Alzheimer's disease.

  4. Study uses targeted sequencing of ABCA7 to identify splicing, stop-gain and intronic risk variants for Alzheimer disease. Study shows that multiple variants in ABCA7 contribute to late-onset Alzheimer's disease risk.

  5. ABCA7 PTC (show F9 Antibodies) mutations play a substantial role in early-onset Alzheimer disease, warranting genetic screening of ABCA7 in genetically unexplained patients.

  6. This study demonstrated that Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-beta40 and Amyloid-beta42 Peptides and ABCA7 Transcription in Cell Culture Models.

  7. The major difference in the pattern of lipid peaks between ABCA7 and ABCA1 (show ABCA1 Antibodies) was the high lysoPC/PC ratio of ABCA7.

  8. Results confirm that ABCA7 loss of function variants are enriched in patients with Alzheimer disease and extend this finding to predicted damaging missense variants

  9. A detailed clinicopathologic description of patients carrying an ABCA7 loss of function mutation: a classical Alzheimer disease phenotype, though with a striking wide onset age range, suggesting the influence of unknown modifying factors

  10. Results suggested that ABCA7 genotypes contribute to the AD risk through involvement in amyloid-beta deposition on in vivo imaging, but not in tau pathology, brain atrophy, or decreased glucose metabolism

ABCA7 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known\; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.

Gene names and symbols associated with ABCA7

  • ATP-binding cassette, sub-family A (ABC1), member 7 (Abca7) antibody
  • ATP binding cassette subfamily A member 7 (ABCA7) antibody
  • ATP binding cassette subfamily A member 7 (Abca7) antibody
  • ATP-binding cassette sub-family A member 7 (LOC100088822) antibody
  • Abc51 antibody
  • ABCA-SSN antibody
  • ABCA7 antibody
  • ABCX antibody

Protein level used designations for ABCA7

ATP-binding cassette sub-family A member 7 , autoantigen SS-N , macrophage ABC transporter , ATP-binding cassette, sub-family A (ABC1), member 7 , ATP-binding cassette, sub-family A, member 7

GENE ID SPECIES
27403 Mus musculus
10347 Homo sapiens
299609 Rattus norvegicus
511762 Bos taurus
455538 Pan troglodytes
485090 Canis lupus familiaris
704976 Macaca mulatta
100088822 Ornithorhynchus anatinus
100623892 Sus scrofa
100726877 Cavia porcellus
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