Achaete-Scute Complex Homolog 3 (Drosophila) Proteins (ASCL3)

Transcriptional repressor.

list all proteins Gene Name GeneID UniProt
Human ASCL3 ASCL3 56676 Q9NQ33
Mouse ASCL3 ASCL3 56787 Q9JJR7
Rat ASCL3 ASCL3 246301  
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Top ASCL3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
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More Proteins for Achaete-Scute Complex Homolog 3 (Drosophila) (ASCL3) Interaction Partners

Mouse (Murine) Achaete-Scute Complex Homolog 3 (Drosophila) (ASCL3) interaction partners

  1. These results demonstrate that Ascl3 marks progenitors that are lineage-committed strictly to microvillar cells and Bowman's glands, and highlight the requirement for these cell types to support OE homeostasis.

  2. Ascl3 knockouts develop smaller salivary glands than wild types, but secrete saliva (show RAG1AP1 Proteins) normally. They display a lower level of cell proliferation, consistent with their smaller size. In the absence of Ascl3, the cells maintain their progenitor function.

  3. These data demonstrate a progenitor-progeny relationship between duct cells and the acinar cell compartment, and identify a population of multipotent progenitor cells, marked by expression of Ascl3, which is capable of generating both gland cell types.

ASCL3 Protein Profile

Protein Summary

Transcriptional repressor. Inhibits myogenesis (By similarity).

Gene names and symbols associated with ASCL3

  • achaete-scute family bHLH transcription factor 3 (ASCL3)
  • achaete-scute family bHLH transcription factor 3 (Ascl3)
  • ASCL3-like protein
  • ASH3A protein
  • bHLHa42 protein
  • HASH3 protein
  • Sgn1 protein

Protein level used designations for ASCL3

ASH-3 , achaete-scute homolog 3 , bHLH transcription factor Sgn-1 (Salivary Glands 1) , bHLH transcriptional regulator Sgn-1 , class A basic helix-loop-helix protein 42 , ICRFP703B1614Q5.4 , ICRFP703N2430Q5.4 , achaete-scute complex homolog-like 3 , mASH-3 , mASH3 , achaete-scute complex homolog 3

GENE ID SPECIES
56676 Homo sapiens
56787 Mus musculus
786757 Bos taurus
101106621 Ovis aries
100728191 Cavia porcellus
246301 Rattus norvegicus
100686513 Canis lupus familiaris
100518920 Sus scrofa
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