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Transcriptional repressor. Additionally we are shipping ASCL3 Antibodies (29) and ASCL3 Kits (12) and many more products for this protein.
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Ascl3 knockouts develop smaller salivary glands than wild types, but secrete saliva (show RAG1AP1 Proteins) normally. They display a lower level of cell proliferation, consistent with their smaller size. In the absence of Ascl3, the cells maintain their progenitor function.
These data demonstrate a progenitor-progeny relationship between duct cells and the acinar cell compartment, and identify a population of multipotent progenitor cells, marked by expression of Ascl3, which is capable of generating both gland cell types.
Transcriptional repressor. Inhibits myogenesis (By similarity).
, achaete-scute homolog 3
, bHLH transcription factor Sgn-1 (Salivary Glands 1)
, bHLH transcriptional regulator Sgn-1
, class A basic helix-loop-helix protein 42
, achaete-scute complex homolog-like 3