anti-Alkaline Phosphatase, Placental (ALP) Antibodies

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). Additionally we are shipping ALP Kits (42) and ALP Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALP 250 P05187
ALP 114108 Q66HS7
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Top anti-ALP Antibodies at antibodies-online.com

Showing 10 out of 383 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ALPP Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate Rabbit Anti-ALPP Antibody  Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated IHC (p), WB ALPP was detected in paraffin-embedded sections of human placenta tissues using rabbit anti- ALPP Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). Western blot analysis of ALPP expression in human placenta extract ( Lane 1). ALPP at 70KD was detected using rabbit anti- ALPP Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of ALP expression in HEK293T (A), Raw264.7 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB ALPP Antibody (N-term) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the ALPP antibody detected the ALPP protein (arrow). Western blot analysis of ALPP (arrow) using rabbit polyclonal ALPP Antibody (N-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ALPP gene. 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (p), WB ALPP Antibody (Center) (ABIN657476) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the ALPP antibody detected the ALPP protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p) 0.125 mL 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of sample using ALPP/ALPPL2 Polyclonal Antibody. 100 μL Available
$363.46
Details
Dog Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Human Mouse Un-conjugated ELISA, IHC, WB Figure 1: Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL 8 to 11 Days
$491.79
Details

Top referenced anti-ALP Antibodies

  1. Human Monoclonal ALP Primary Antibody for ICC, FACS - ABIN258034 : Leitner, Szlauer, Ellinger, Ellinger, Zimmer, Fuchs: Placental alkaline phosphatase expression at the apical and basal plasma membrane in term villous trophoblasts. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001 (PubMed)
    Show all 11 Pubmed References

  2. Human Monoclonal ALP Primary Antibody for IHC, ELISA - ABIN965542 : Llinas, Stura, Ménez, Kiss, Stigbrand, Millán, Le Du: Structural studies of human placental alkaline phosphatase in complex with functional ligands. in Journal of molecular biology 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ALP Primary Antibody for WB - ABIN2715939 : Lv, Yang, Wang, Yu, Huang, Ye: The WNT7B protein promotes the migration and differentiation of human dental pulp cells partly through WNT/beta-catenin and c-Jun N-terminal kinase signalling pathways. in Archives of oral biology 2018 (PubMed)

  4. Cow (Bovine) Polyclonal ALP Primary Antibody for IHC, WB - ABIN2777088 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal ALP Primary Antibody for IHC, ELISA - ABIN968956 : Chen, Anderson, Hiroi, Medof: Proprotein interaction with the GPI transamidase. in Journal of cellular biochemistry 2003 (PubMed)

  6. Human Monoclonal ALP Primary Antibody for ELISA, IHC (f) - ABIN94454 : Millán, Stigbrand: Antigenic determinants of human placental and testicular placental-like alkaline phosphatases as mapped by monoclonal antibodies. in European journal of biochemistry / FEBS 1983 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal ALP Primary Antibody for ELISA, ID - ABIN5572442 : Han, Yang, Li, Li, Zheng, Yu, Zhang, Zheng, Yi, Li, Guo, Zhou: RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia. in Cell and tissue research 2016 (PubMed)

More Antibodies against ALP Interaction Partners

Human Alkaline Phosphatase, Placental (ALP) interaction partners

  1. This meta-analysis suggests that high serum ALP level is obviously associated with lower OS rate in patients with osteosarcoma, and it is an effective biomarker of prognosis.

  2. Concentrations of PLAP were elevated in gingival crevicular fluid of patients with pre-eclampsia.

  3. SALL4 also outperformed PLAP on a small sample of cytology blocks. Although SALL4 is not entirely specific, it is a highly sensitive marker with strong diffuse nuclear reactivity in the majority of MGCTs in the posttreatment setting, at significantly higher levels than PLAP

  4. Quantum-mechanical computational methods were employed to study the catalytic mechanism of human placental AP (PLAP). An active-site model was used, constructed on the basis of the X-ray crystal structure of the enzyme.

  5. term placental explants, but not their conditioned medium, can de-phosphorylate IGFBP-1 through the action of placental alkaline phosphatase

  6. Anti-PLAP antibodies may serve as a modular building blocks for the development of targeted therapeutic products, armed with cytotoxic drugs, radionuclides or cytokines as payloads.

  7. A candidate gene, ALPP, encoding the placental alkaline phosphatase, was identified as being potentially involved in recurrent spontaneous abortion.

  8. The objective of the following study was to record the specificity and sensitivity of alpha5(IV) loss, smoothelin expression and PLAP expression as markers of gastrointestinal smooth muscle neoplasms

  9. Data indicate that p180 is required for the efficient targeting of placental alkaline phosphatase (ALPP) mRNA to the endoplasmic reticulum (ER).

  10. Calculation of the electrostatic potentials within the active site of human placental alkaline phosphatase also suggests that the local positive electrostatic environment may account for its capability to distinguish various substrates

  11. High serum alkaline phosphatase cooperating with MMP-9 is associated with metastasis in patients with primary osteosarcoma.

  12. PLAP exerts a positive effect on DNA replication and acts as a proliferative factor in trophoblastic cells.

  13. The proximity of undifferentiated gonadal tissue with the tumors as well as the immunostaining patterns (PLAP+, OCT3/4+, and CD117/KIT+) suggests that germ cells found in them are a risk factor for gonadal tumors.

  14. the catalytic mechanism of human placental alkaline phosphatase

  15. Data show that serum alkaline phosphatase, Gleason score, and intensity of bone metastasis are important and statistically significant prognostic factors, and affects time to progression and life time.

  16. at a certain time point during adrenocortical development, some fetal zone cells survive owing to defective apoptosis and develop into childhood ACT, maintaining some characteristics of the embryonal period, such as PLAP expression

  17. Serum total calcium (r -0.1362, p<0.001), serum inorganic phosphate (r -0.45, p<0.001) and serum alkaline phosphatase (r -0.5587, p<0.001) have shown inverse relationship with age.

  18. High serum alkaline phosphatase is associated with chronic kidney disease.

  19. differential expression of Pl(1) and Pl(2) probably results from linkage disequilibrium with the sequence variation rs2014683G>A in the ALPP gene promoter that was shown to have allele-specific binding patterns to placental nuclear proteins.

  20. structure of placental alkaline phosphatase with pNPP contained only p-nitrophenol in three distinct sites, while the structure with 5'-AMP contained the p-nitrophenyl group in two of the sites instead of 5'-AMP

ALP Antigen Profile

Protein Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Gene names and symbols associated with ALP

  • bacterial alkaline phosphatase (phoA) antibody
  • alkaline phosphatase, placental (ALPP) antibody
  • alkaline phosphatase, placental type (LOC100436725) antibody
  • C-C motif chemokine ligand 27 (CCL27) antibody
  • alkaline phosphatase, liver/bone/kidney (alpl) antibody
  • alkaline phosphatase (alp) antibody
  • alkaline phosphatase, intestinal (ALPI) antibody
  • PDZ and LIM domain 3 (Pdlim3) antibody
  • alkaline phosphatase, placental (Alpp) antibody
  • Actn2lp antibody
  • Akp2 antibody
  • Alp antibody
  • ALPI antibody
  • CTACK antibody
  • DDBDRAFT_0205491 antibody
  • DDBDRAFT_0231570 antibody
  • DDB_0205491 antibody
  • DDB_0231570 antibody
  • ECK0378 antibody
  • ESkine antibody
  • ILC antibody
  • JW0374 antibody
  • PALP antibody
  • PLAP antibody
  • PLAP-1 antibody
  • psiA antibody
  • zgc:56672 antibody

Protein level used designations for ALP

Regan isozyme , alkaline phosphatase Regan isozyme , alkaline phosphatase, placental type , alkaline phosphomonoesterase , glycerophosphatase , placental alkaline phosphatase 1 , bacterial alkaline phosphatase , alkaline phosphatase, placental (Regan isozyme) , C-C motif chemokine 27 , skinkine , tissue-nonspecific alkaline phosphatase , alkaline phosphatase , alkaline phosphatase, intestinal , PDZ and LIM domain protein 3 , SK-2 , actinin alpha 2 associated LIM protein , actinin-associated LIM protein , alpha-actinin-2-associated LIM protein , rCG23846-like

GENE ID SPECIES
945041 Escherichia coli str. K-12 substr. MG1655
250 Homo sapiens
7955440 Escherichia coli BW2952
8180246 Escherichia coli BL21(DE3)
8215011 Escherichia coli O157:H7 str. TW14359
100436725 Pongo abelii
445453 Sus scrofa
393982 Danio rerio
445994 Takifugu rubripes
8621605 Dictyostelium discoideum AX4
403736 Canis lupus familiaris
114108 Rattus norvegicus
100359675 Rattus norvegicus
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