anti-Amphiphysin (AMPH) Antibodies

AMPH encodes a protein associated with the cytoplasmic surface of synaptic vesicles. Additionally we are shipping Amphiphysin Proteins (12) and Amphiphysin Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AMPH 273 P49418
AMPH 218038 Q7TQF7
AMPH 60668 O08838
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Top anti-Amphiphysin Antibodies at

Showing 10 out of 155 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AMPH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated IHC (p), WB WB Image Amphiphysin antibody [N1N2], N-term detects AMPH protein by Western blot analysis. A. 50 µg mouse brain lysate/extract 7.5 % SDS-PAGE Amphiphysin antibody [N1N2], N-term , dilution: 1:1000 IHC-P Image Amphiphysin antibody [N1N2], N-term detects AMPH protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. Amphiphysin antibody [N1N2], N-term , dilution: 1:500. 100 μL 3 to 4 Days
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Muscle, antibody was diluted at 1:100. 100 μL Available
Cow Rabbit Un-conjugated WB Western blot analysis of Amphiphysin 1 expression in SHSYS5 (A), mouse brain (B), PC12 (C) whole cell lysates. 200 μL 13 to 14 Days
Cow Mouse Un-conjugated IHC (p), IP, WB 50 μg 6 to 8 Days
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with AMPH antibody ABIN351482 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-AMPH / Amphiphysin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of specific cells using Amphiphysin I Polyclonal Antibody. 100 μL Available
Human Rabbit Un-conjugated ICC, IP, IHC, WB dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2) Immunocytochemistry on cultured hippocampus neurons (dilution 1 : 500). Immunoreactivity was revealed with a fluorochromated secondary antibody. 200 μL 5 to 6 Days
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days

Top referenced anti-Amphiphysin Antibodies

  1. Human Polyclonal Amphiphysin Primary Antibody for ICC, IP - ABIN1742262 : Scott, Tabarean, Tang, Cartier, Masliah, Roy: A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal Amphiphysin Primary Antibody for IF, IP - ABIN532588 : Wigge, McMahon: The amphiphysin family of proteins and their role in endocytosis at the synapse. in Trends in neurosciences 1998 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Amphiphysin Primary Antibody for IF, IP - ABIN532579 : Zhang, Zelhof: Amphiphysins: raising the BAR for synaptic vesicle recycling and membrane dynamics. Bin-Amphiphysin-Rvsp. in Traffic (Copenhagen, Denmark) 2002 (PubMed)
    Show all 2 Pubmed References

  4. Dog (Canine) Polyclonal Amphiphysin Primary Antibody for ELISA, WB - ABIN547676 : Sommer, Weishaupt, Brinkhoff, Biko, Wessig, Gold, Toyka: Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin. in Lancet 2005 (PubMed)

More Antibodies against Amphiphysin Interaction Partners

Fruit Fly (Drosophila melanogaster) Amphiphysin (AMPH) interaction partners

  1. Co-immunoprecipitation analysis supports association between Ma2/d and Amph, and indirectly with Msp300. Ma2/d, in association with Msp300 and Amph, mediates interactions between the SR and the nuclear membrane.

  2. Our study indicates that the H0 helix and the BAR tip are necessary for efficient and organized self-assembly of amphiphysin/N-BAR

  3. Cleavage furrow tips tubule formation requires the BAR domain of amphiphysin.

  4. This study challenges the notion that synaptic Amphiphysin is involved exclusively in endocytosis and suggests a novel role for this protein in postsynaptic exocytosis

  5. the structure of the Drosophila amphiphysin BAR domain was solved; the universal and minimal BAR domain is a dimerization, membrane-binding, and curvature-sensing module

Human Amphiphysin (AMPH) interaction partners

  1. the anti-oncogenic function of AMPH-1 in lung cancer in vitro and in vivo, is reported.

  2. The data show that the dynamin-amphiphysin helices are rearranged to form clusters upon GTP hydrolysis and membrane constriction occurs at protein-uncoated regions flanking the clusters.

  3. We show that AMPH-1/BIN1 binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 in both species. We propose that BIN1 has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies.

  4. It is a nerve protein and its autoantibody causes paraneoplastic neurological syndromes.

  5. AMPH1 protein level is reduced in transgenic mouse brain proteins. in the brainstem of nontransgenic and terminally ill JNPL3 transgenic mice.

  6. We propose that antibody-mediated amphiphysin deficiency may account for anxiety behavior in stiff person syndrome

  7. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  8. structure-based approach to prediction of peptide-binding behavior of SH3 domain of amphiphysin-1: statistical modeling

  9. investigation of binding affinities of decapeptide ligands with amphiphysin SH3 domain using QSAR models

  10. Female patient with amphiphysin autoantibodies and siff leg syndrome due to small cell cancer of the lung.

  11. Amphiphysin I (Amph I) is a minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase substrate. Amph I phosphorylation changes the recruitment of endophilin at the endocytic sites.

  12. This study demonstrates that the analysis of the molecular interaction energy components between peptides and the SH3 domain can successfully characterize the binding interface.

  13. Analyses of Gaussian distribution models showed that diversified properties contribute to the interactions between the SH3 domain and of amphiphysin and peptides.

Mouse (Murine) Amphiphysin (AMPH) interaction partners

  1. Data indicate that dynamin, clathrin, adaptor protein complex-2 (AP2), and amphiphysin contribute to the depolarization-evoked entry in endocytosis.

  2. Amph1 is the cytoplasmic substrate for CDKL5 and that its phosphorylation may play crucial roles in the neuronal development.

  3. amphiphysin IIm has a role in survival of Chlamydia pneumoniae in macrophages

  4. calpain-dependent cleavage of amphiphysin I inhibits synaptic vesicle endocytosis during neural hyperexcitation and demonstrate a novel post-translational regulation of endocytosis

  5. results suggest that amphiphysin 1 and dynamin 2 are involved in TBC formation and spermatid release at Sertoli cells

  6. amphiphysin 1 is important in the regulation of actin dynamics

  7. As amphiphysin is involved in the regulation of endocytosis, phosphorylation at this site may play a role in the regulated re-uptake of synaptic vesicles after neurotransmitter release.

  8. amphiphysin interaction with N-WASP regulates actin assembly

Zebrafish Amphiphysin (AMPH) interaction partners

  1. CDKL5 phosphorylates amphiphysin 1 at Ser-285 and Ser-293 sites.Splice variants of Amph1 showed different spatial and temporal expressions.

Amphiphysin (AMPH) Antigen Profile

Protein Summary

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

Gene names and symbols associated with anti-Amphiphysin (AMPH) Antibodies

  • amphiphysin (AMPH) antibody
  • Amphiphysin (Amph) antibody
  • amphiphysin (amph) antibody
  • amphiphysin (LOC409851) antibody
  • amphiphysin (Amph) antibody
  • amphiphysin L homeolog (amph.L) antibody
  • amphiphysin (LOC100343468) antibody
  • Amp antibody
  • Amph antibody
  • Amph1 antibody
  • CG8604 antibody
  • Damp antibody
  • damph antibody
  • Dmel\\CG8604 antibody
  • GB16263 antibody
  • wu:fq25h04 antibody
  • zgc:73193 antibody

Protein level used designations for anti-Amphiphysin (AMPH) Antibodies

Amph-PA , Amph-PB , Amph-PC , CG8604-PA , CG8604-PB , CG8604-PC , amphiphysin , amphiphysin-like , amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen) , amphiphysin I , amphiphysin 1 , amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)

100062724 Equus caballus
36383 Drosophila melanogaster
463363 Pan troglodytes
704559 Macaca mulatta
100125136 Xenopus (Silurana) tropicalis
100391968 Callithrix jacchus
100446471 Pongo abelii
409851 Apis mellifera
100015587 Monodelphis domestica
100483982 Ailuropoda melanoleuca
100600277 Nomascus leucogenys
273 Homo sapiens
218038 Mus musculus
60668 Rattus norvegicus
475877 Canis lupus familiaris
614722 Bos taurus
393804 Danio rerio
432150 Xenopus laevis
420761 Gallus gallus
100626324 Sus scrofa
100343468 Oryctolagus cuniculus
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