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AMPH encodes a protein associated with the cytoplasmic surface of synaptic vesicles. Additionally we are shipping Amphiphysin Antibodies (151) and Amphiphysin Proteins (12) and many more products for this protein.
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Our study indicates that the H0 helix and the BAR tip are necessary for efficient and organized self-assembly of amphiphysin/N-BAR
Cleavage furrow tips tubule formation requires the BAR domain of amphiphysin.
This study challenges the notion that synaptic Amphiphysin is involved exclusively in endocytosis and suggests a novel role for this protein in postsynaptic exocytosis
the structure of the Drosophila amphiphysin BAR domain was solved; the universal and minimal BAR domain is a dimerization, membrane-binding, and curvature-sensing module
The data show that the dynamin (show DNM1 ELISA Kits)-amphiphysin helices are rearranged to form clusters upon GTP (show AK3 ELISA Kits) hydrolysis and membrane constriction occurs at protein-uncoated regions flanking the clusters.
We show that AMPH-1/BIN1 (show BIN1 ELISA Kits) binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 in both species. We propose that BIN1 (show BIN1 ELISA Kits) has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies.
It is a nerve protein and its autoantibody causes paraneoplastic neurological syndromes.
AMPH1 protein level is reduced in transgenic mouse brain proteins. in the brainstem of nontransgenic and terminally ill JNPL3 transgenic mice.
We propose that antibody-mediated amphiphysin deficiency may account for anxiety behavior in stiff person syndrome
structure-based approach to prediction of peptide-binding behavior of SH3 domain (show ITSN1 ELISA Kits) of amphiphysin-1: statistical modeling
investigation of binding affinities of decapeptide ligands with amphiphysin SH3 domain (show ITSN1 ELISA Kits) using QSAR models
Female patient with amphiphysin autoantibodies and siff leg syndrome due to small cell cancer of the lung.
Amphiphysin I (Amph I) is a minibrain (show DYRK1A ELISA Kits) kinase/dual-specificity tyrosine phosphorylation-regulated (show PHAX ELISA Kits) kinase substrate. Amph I phosphorylation changes the recruitment of endophilin at the endocytic sites.
This study demonstrates that the analysis of the molecular interaction energy components between peptides and the SH3 domain (show ITSN1 ELISA Kits) can successfully characterize the binding interface.
Data indicate that dynamin (show DNM1 ELISA Kits), clathrin, adaptor protein complex-2 (AP2 (show TFAP2A ELISA Kits)), and amphiphysin contribute to the depolarization-evoked entry in endocytosis.
Amph1 is the cytoplasmic substrate for CDKL5 and that its phosphorylation may play crucial roles in the neuronal development.
amphiphysin IIm has a role in survival of Chlamydia pneumoniae in macrophages
calpain-dependent cleavage of amphiphysin I inhibits synaptic vesicle endocytosis during neural hyperexcitation and demonstrate a novel post-translational regulation of endocytosis
results suggest that amphiphysin 1 and dynamin 2 (show DNM2 ELISA Kits) are involved in TBC (show TBC1D1 ELISA Kits) formation and spermatid release at Sertoli cells
amphiphysin 1 is important in the regulation of actin dynamics
As amphiphysin is involved in the regulation of endocytosis, phosphorylation at this site may play a role in the regulated re-uptake of synaptic vesicles after neurotransmitter release.
amphiphysin interaction with N-WASP regulates actin assembly
CDKL5 phosphorylates amphiphysin 1 at Ser (show SIGLEC1 ELISA Kits)-285 and Ser (show SIGLEC1 ELISA Kits)-293 sites.Splice variants of Amph1 showed different spatial and temporal expressions.
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.
, amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen)
, amphiphysin I
, amphiphysin 1
, amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)