anti-Anaphase Promoting Complex Subunit 1 (ANAPC1) Antibodies

ANAPC1 encodes a subunit of the anaphase-promoting complex.

list all antibodies Gene Name GeneID UniProt
Anti-Human ANAPC1 ANAPC1 64682 Q9H1A4
Anti-Rat ANAPC1 ANAPC1 311412  
Anti-Mouse ANAPC1 ANAPC1 17222 P53995
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Top anti-Anaphase Promoting Complex Subunit 1 Antibodies at antibodies-online.com

Showing 10 out of 143 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of ANAPC1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of ANAPC1 expression in HeLa (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of ANAPC1 (pS688) staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the prima Immunohistochemical analysis of ANAPC1 (pS688) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then inc 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using APC1 (Ab-355) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using APC1 (Phospho-Ser355) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, FACS, IHC, IHC (p), WB Western Blot: Apc1 Antibody [NBP1-77375] - analysis of APC1 in SK-N-SH cell lysate with APC1 antibody at (A) 1 and (B) 2 ug/ml. Flow Cytometry: Apc1 Antibody [NBP1-77375] - APC1 expression in human lymphocytes. Image from verified customer review. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Cow Rabbit Un-conjugated IHC (p), IHC, ELISA, WB 0.1 mg Log in to see 7 to 9 Days
$585.06
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using APC1 (Phospho-Ser688) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of COS7 cells, using APC1 (Phospho-Ser688) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using APC1 (Ab-688) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using APC1 (Ab-688) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Chicken Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$619.30
Details

Top referenced anti-Anaphase Promoting Complex Subunit 1 Antibodies

  1. Human Polyclonal ANAPC1 Primary Antibody for IP, WB - ABIN257717 : Schiffman, Rodriguez, Chen, Wacholder, Herrero, Hildesheim, Desalle, Befano, Yu, Safaeian, Sherman, Morales, Guillen, Alfaro, Hutchinson, Solomon, Castle, Burk: A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia. in Cancer research 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal ANAPC1 Primary Antibody for ELISA, FACS - ABIN4281012 : Spurlock, Tossberg, Olsen, Aune: Cutting Edge: Chronic NF-κB Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

More Antibodies against Anaphase Promoting Complex Subunit 1 Interaction Partners

Human Anaphase Promoting Complex Subunit 1 (ANAPC1) interaction partners

  1. Data show that FZR1 (Fzr (show FZR1 Antibodies)), a cofactor of the multi-subunit E3 ligase complex anaphase-promoting complex/cyclosome (APC (show APC Antibodies)/C), represents a therapeutic target in myeloma.

  2. in the Alzheimer's disease (AD)mouse model APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies), lower cdh1 (show CDH1 Antibodies) levels were observed in pyramidal neurons in CA1 (show CA1 Antibodies) when compared to age-matched wildtype mice. In this review, we provide a complete list of APC (show APC Antibodies)/C substrates that are involved in the nervous system and we discuss their functions. We also summarize recent studies that show neurobiological effects in cdh1 (show CDH1 Antibodies) knockout mouse models.

  3. cryo-EM structure of an APC (show APC Antibodies)/C-Cdh1 (show CDH1 Antibodies) complex with Apc1 (show SLC25A24 Antibodies)(WD40 (show DCAF12L2 Antibodies)) deleted showed that the mutant APC (show APC Antibodies)/C is locked into an inactive conformation in which the UbcH10 (show UBE2C Antibodies)-binding site of the catalytic module is inaccessible. Additionally, an EM density for Apc15 (show ANAPC15 Antibodies) is not visible

  4. The ABBA (show MTSS1L Antibodies)-KEN (show PCNT Antibodies)-ABBA (show MTSS1L Antibodies) amino acid motif cassette holds the Mitotic Checkpoint (show BUB3 Antibodies) Complex (MCC (show MCC Antibodies)) onto the Anaphase-Promoting Complex-Cyclosome (APC (show APC Antibodies)/C) by binding the two Cdc20 (show CDC20 Antibodies) molecules in the MCC (show MCC Antibodies)-APC (show APC Antibodies)/C complex.

  5. findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 (show PAX3 Antibodies) may be a strategy for treating melanoma.

  6. Human Cytomegalovirus UL21a but not UL97 can disrupt APC (show APC Antibodies)/C function, leading to the accumulation of substrates and that UL21a is necessary and sufficient to induce the degradation of APC1 (show SLC25A24 Antibodies), in addition to the previously reported APC4 (show ANAPC4 Antibodies) and APC5 (show ANAPC5 Antibodies).

  7. Data indicate that regulation of Rad17 (show RAD17 Antibodies) turnover is through the Cdh1 (show CDH1 Antibodies)/anaphase-promoting complex pathway in breast cancer cells.

  8. EYA1 (show EYA1 Antibodies) is efficiently degraded during mitotic exit in a ANAPC1-dependent manner and these two proteins physically interact.

  9. analysis of ubiquitylation of p53 (show TP53 Antibodies) by the APC (show APC Antibodies)/C inhibitor Trim39 (show TRIM39 Antibodies)

  10. Single nucleotide polymorhpisms of ANAPC1 were associated with nicotine dependence.

Mouse (Murine) Anaphase Promoting Complex Subunit 1 (ANAPC1) interaction partners

  1. findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 (show PAX3 Antibodies) may be a strategy for treating melanoma.

  2. EYA1 (show EYA1 Antibodies) is efficiently degraded during mitotic exit in a ANAPC1-dependent manner and these two proteins physically interact.

Anaphase Promoting Complex Subunit 1 (ANAPC1) Antigen Profile

Protein Summary

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.

Gene names and symbols associated with ANAPC1

  • anaphase promoting complex subunit 1 (ANAPC1) antibody
  • anaphase promoting complex subunit 1 (Anapc1) antibody
  • anaphase promoting complex subunit 1 (CC1G_09696) antibody
  • anaphase promoting complex subunit 1 (anapc1) antibody
  • E3 ubiquitin ligase (EMB2771) antibody
  • 2610021O03Rik antibody
  • AI047775 antibody
  • AI853536 antibody
  • Apc1 antibody
  • AW547281 antibody
  • DDBDRAFT_0186456 antibody
  • DDBDRAFT_0234263 antibody
  • DDB_0186456 antibody
  • DDB_0234263 antibody
  • EMBRYO DEFECTIVE 2771 antibody
  • Mcpr antibody
  • MOP10.10 antibody
  • MOP10_10 antibody
  • tsg24 antibody

Protein level used designations for ANAPC1

anaphase-promoting complex 1 (meiotic checkpoint regulator) , anaphase-promoting complex subunit 1 , cyclosome subunit 1 , mitotic checkpoint regulator , testis-specific gene 24 protein , anaphase promoting complex subunit 1 , meiotic check point regulator

GENE ID SPECIES
64682 Homo sapiens
311412 Rattus norvegicus
421228 Gallus gallus
475750 Canis lupus familiaris
535565 Bos taurus
6010702 Coprinopsis cinerea okayama7130
8625062 Dictyostelium discoideum AX4
100031108 Monodelphis domestica
17222 Mus musculus
100051869 Equus caballus
100519830 Sus scrofa
830439 Arabidopsis thaliana
100348299 Oryctolagus cuniculus
100725716 Cavia porcellus
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