Anaphase Promoting Complex Subunit 7 Proteins (ANAPC7)

ANAPC7 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. Additionally we are shipping ANAPC7 Antibodies (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANAPC7 51434 Q9UJX3
ANAPC7 56317 Q9WVM3
Rat ANAPC7 ANAPC7 304490  
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Top ANAPC7 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details

ANAPC7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Anaphase Promoting Complex Subunit 7 (ANAPC7) Interaction Partners

Human Anaphase Promoting Complex Subunit 7 (ANAPC7) interaction partners

  1. The results showed that APC2 and APC7 subunits were both over expressed in cancer cell lines

  2. Data indicate that additional density present in the anaphase-promoting complex (APC (show APC Proteins)/C) structure, proximal to Apc3/Cdc27 of the (tetratricopeptide repeat) lobe, is assigned to the TPR subunit Apc7, a subunit specific to vertebrate APC (show APC Proteins)/C.

  3. Studies indicate that APC (show APC Proteins)/C(Cdh1 (show CDH1 Proteins)) is required to maintain genomic stability.

  4. dysregulation of APC (show APC Proteins) activity, possibly through downregulation of APC7, may be associated with tumorigenesis in breast cancer

  5. APC5 (show ANAPC5 Proteins) and APC7 suppress E1A (show BCKDHA Proteins)-mediated transformation in a CBP/p300 (show CREBBP Proteins)-dependent manner, indicating that these components of the APC (show APC Proteins)/C may be targeted during cellular transformation

  6. Expression of ANAPC7 in fibroadenomas and phylloides tumors of breast is reported.

  7. The crystal structure of quad mutant of nApc7 (N-terminal fragment, residues 1-147) of human Apc7 at a resolution of 2.5 A, is reported.

ANAPC7 Protein Profile

Protein Summary

This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ANAPC7

  • anaphase promoting complex subunit 7 (anapc7)
  • anaphase promoting complex subunit 7 (ANAPC7)
  • anaphase promoting complex subunit 7 L homeolog (anapc7.L)
  • anaphase promoting complex subunit 7 (Anapc7)
  • tetratricopeptide repeat (TPR)-containing protein (APC7)
  • APC7 protein
  • AW545589 protein
  • DDBDRAFT_0184417 protein
  • DDBDRAFT_0235159 protein
  • DDB_0184417 protein
  • DDB_0235159 protein
  • si:ch211-127h20.1 protein
  • T7F6.26 protein
  • T7F6_26 protein

Protein level used designations for ANAPC7

anaphase promoting complex subunit 7 , anaphase-promoting complex subunit 7 , cyclosome subunit 7 , prediabetic NOD sera-reactive autoantigen

GENE ID SPECIES
549081 Xenopus (Silurana) tropicalis
8628702 Dictyostelium discoideum AX4
467128 Pan troglodytes
558402 Danio rerio
446574 Xenopus laevis
416838 Gallus gallus
51434 Homo sapiens
486264 Canis lupus familiaris
535072 Bos taurus
56317 Mus musculus
304490 Rattus norvegicus
818495 Arabidopsis thaliana
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